Results 1 to 10 of about 85,969 (264)

Discrepancy between international normalized ratio measurements in a heterozygous carrier of F10:p.Gly244Arg with recurrent venous thromboembolism: a case report [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: The international normalized ratio (INR) is designed to monitor vitamin K antagonist (VKA) treatment. Before patients start a self-managing VKA program, parallel measurements are conducted to compare point-of-care testing (POCT) INR with ...
Nikolaj Julian Skrøder Nytofte, Emil List Larsen   +1 more
doaj   +2 more sources

Impact of thromboplastin reagents on monitoring INR in a patient with triple-positive antiphospholipid syndrome: a case report [PDF]

Frontiers in Immunology
IntroductionAntiphospholipid syndrome (APS) is an autoimmune disease characterized by a hypercoagulable state and recurrent thromboembolism (TE). Patients with triple-positive antiphospholipid antibodies (APAs) are at the highest risk of TE.
Lóránt Varju, Lóránt Varju, Zsuzsa Bagoly, Zsuzsa Bagoly, Éva Ajzner, Rita Orbán-Kálmándi, Rita Orbán-Kálmándi, Anna Zsófia Kádár, Anna Zsófia Kádár, Judit Nevelős, Péter Ilonczai   +10 more
doaj   +2 more sources

Identifying the silent deficiency: Severe Factor XI deficiency in an asymptomatic patient with isolated prolonged activated partial thromboplastin time—A case report [PDF]

SAGE Open Medical Case Reports
Assessing a patient with a suspected bleeding disorder is a complex aspect of hematology. Prolonged activated partial thromboplastin time often indicates a coagulation factor deficiency or inhibitor and warrants detailed evaluation. Factor XI deficiency,
Awni Alshurafa, Mahmoud Draidi, Feryal Ibrahim, Shehab F. Mohamed, Mohamed A. Yassin   +4 more
doaj   +2 more sources

A Novel Thromboplastin-Based Rat Model of Ischemic Stroke

Brain Sciences, 2021
The thromboembolic ischemia model is one of the most applicable for studying ischemic stroke in humans. The aim of this study was to develop a novel thromboembolic stroke model, allowing, by affordable tools, to reproduce cerebral infarction in rats.
Irina V. Ostrova, Sergei N. Kalabushev, Ivan A. Ryzhkov, Zoya I. Tsokolaeva   +3 more
doaj   +1 more source

The role of hemostatic changes in the pathogenesis of diabetic retinopathy

Journal of Education, Health and Sport, 2022
Introduction: The paper presents the results of the hemostasis system of rats with experimental diabetic retinopathy. Material and methods: Experimental studies were performed on white Wistar rats, which were divided into 2 groups: 1st group – intact
Nataliya Preys, Ivan Savytskyi
doaj   +1 more source

Lupus Antibody Mimicking Reduced Plasmatic Coagulation in a Patient With Atrial Fibrillation and Ischemic Stroke

Frontiers in Neurology, 2020
Background: Lupus anticoagulant (LA) owns procoagulant properties in vivo and prolongs phospholipid-dependent clotting times in vitro. The prolonged in vitro clotting time can be misinterpreted as a bleeding disorder.
Aydin Huseynov, Aydin Huseynov, Verena Haselmann, Maximillian Kittel, Thomas Bertsch, Angelika Alonso, Michael Neumaier, Martin Borggrefe, Martin Borggrefe, Ursula Hoffmann, Ursula Hoffmann   +10 more
doaj   +1 more source

Comparative Study and Analysis of Clotting Profiles Between Covid-19 And Non-Covid-19 Patients In Barau Dikko Teaching Hospital, Kaduna

UMYU Journal of Microbiology Research, 2021
Coronavirus disease 2019 (COVID-19) is associated with coagulation abnormalities—disordered hemostasis and high thrombotic risk. The aim of the study was to compare and analyze the clotting profiles between COVID-19 and non-COVID-19 ...
Abdulfatai, K., Abdullahi, B., Jaafaru, I. A., Ezeh, J. N., Haruna, D. S., Achi, M. F.   +5 more
doaj   +1 more source

Tissue Factor-Expressing Tumor-Derived Extracellular Vesicles Activate Quiescent Endothelial Cells via Protease-Activated Receptor-1

Frontiers in Oncology, 2017
Tissue factor (TF)-expressing tumor-derived extracellular vesicles (EVs) can promote metastasis and pre-metastatic niche formation, but the mechanisms by which this occurs remain largely unknown. We hypothesized that generation of activated factor X (FXa)
Sara P. Y. Che, Jeannie Y. Park, Tracy Stokol   +2 more
doaj   +1 more source

Thromboplastin Bilbao: Reproducibility and Sensitivity of a Spanish Thromboplastin [PDF]

Pathophysiology of Haemostasis and Thrombosis, 2002
Prothrombin time (PT) is the control test for oral anticoagulant therapy as well as the screening test for defects of the extrinsic pathway of coagulation. Its responsiveness to decreased extrinsic clotting factors depends on the source and type of tissue factor thromboplastin extract. In 1994, a rabbit brain thromboplastin – Thromboplastin Bilbao (TBi)
M, Vacas, M J, Aguirrebeitia, P J, Lafuente, I, Unanue, J A, Iriarte   +4 more
openaire   +2 more sources

A comparison of two techniques of cell block preparation

Journal of Pathology of Nepal, 2019
Background: Cell block technique is a method of preparing cytological material so that it can be processed, sectioned, stained, and viewed as a histology section.
Anita Kasichhwa, Shreya Shrivastav, Ayushi Agrawal   +2 more
doaj   +1 more source