Results 1 to 10 of about 100,512 (385)

The Thromboplastin Generation Test [PDF]

open access: yesJournal of Clinical Pathology, 1953
Physiological coagulation is dependent on the formation of a powerful thromboplastin within the blood.
A. S. Douglas, Rosemary Biggs
openaire   +4 more sources

The Varied Sensitivity of Partial Thromboplastin and Prothrombin Time Reagents in the Demonstration of the Lupus‐Like Anticoagulant [PDF]

open access: greenScandinavian Journal of Haematology, 1979
An acquired inhibitor of blood coagulation, similar to that described in patients with Systemic Lupus Erythematosus (SLE), was detected during routine coagulation screening in 10 patients who did not meet the criteria for a diagnosis of SLE.
P.M. Mannucci   +3 more
openalex   +2 more sources

Interference of lupus anticoagulant causing antiprothrombin and anti–beta-2-glycoprotein I antibodies on international normalized ratio measurements: comparative analysis of international normalized ratio methods [PDF]

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Life-long vitamin K antagonist (VKA) therapy is recommended as a standard of care in antiphospholipid syndrome (APS) patients with thrombosis.
Rachel Gehlen   +7 more
doaj   +2 more sources

A Novel Thromboplastin-Based Rat Model of Ischemic Stroke

open access: yesBrain Sciences, 2021
The thromboembolic ischemia model is one of the most applicable for studying ischemic stroke in humans. The aim of this study was to develop a novel thromboembolic stroke model, allowing, by affordable tools, to reproduce cerebral infarction in rats.
Irina V. Ostrova   +3 more
doaj   +1 more source

The role of hemostatic changes in the pathogenesis of diabetic retinopathy

open access: yesJournal of Education, Health and Sport, 2022
Introduction: The paper presents the results of the hemostasis system of rats with experimental diabetic retinopathy. Material and methods: Experimental studies were performed on white Wistar rats, which were divided into 2 groups: 1st group – intact
Nataliya Preys, Ivan Savytskyi
doaj   +1 more source

Thromboplastin Bilbao: Reproducibility and Sensitivity of a Spanish Thromboplastin [PDF]

open access: yesPathophysiology of Haemostasis and Thrombosis, 2002
Prothrombin time (PT) is the control test for oral anticoagulant therapy as well as the screening test for defects of the extrinsic pathway of coagulation. Its responsiveness to decreased extrinsic clotting factors depends on the source and type of tissue factor thromboplastin extract. In 1994, a rabbit brain thromboplastin – Thromboplastin Bilbao (TBi)
I. Unanue   +4 more
openaire   +3 more sources

Lupus Antibody Mimicking Reduced Plasmatic Coagulation in a Patient With Atrial Fibrillation and Ischemic Stroke

open access: yesFrontiers in Neurology, 2020
Background: Lupus anticoagulant (LA) owns procoagulant properties in vivo and prolongs phospholipid-dependent clotting times in vitro. The prolonged in vitro clotting time can be misinterpreted as a bleeding disorder.
Aydin Huseynov   +10 more
doaj   +1 more source

Comparative Study and Analysis of Clotting Profiles Between Covid-19 And Non-Covid-19 Patients In Barau Dikko Teaching Hospital, Kaduna

open access: yesUMYU Journal of Microbiology Research, 2021
Coronavirus disease 2019 (COVID-19) is associated with coagulation abnormalities- disordered hemostasis and high thrombotic risk. The aim of the study was to compare and analyze the clotting profiles between COVID-19 and non-COVID-19 patients in Barau ...
Abdulfatai K   +5 more
doaj   +1 more source

Tissue Factor-Expressing Tumor-Derived Extracellular Vesicles Activate Quiescent Endothelial Cells via Protease-Activated Receptor-1

open access: yesFrontiers in Oncology, 2017
Tissue factor (TF)-expressing tumor-derived extracellular vesicles (EVs) can promote metastasis and pre-metastatic niche formation, but the mechanisms by which this occurs remain largely unknown. We hypothesized that generation of activated factor X (FXa)
Sara P. Y. Che   +2 more
doaj   +1 more source

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