Discrepancy between international normalized ratio measurements in a heterozygous carrier of F10:p.Gly244Arg with recurrent venous thromboembolism: a case report [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: The international normalized ratio (INR) is designed to monitor vitamin K antagonist (VKA) treatment. Before patients start a self-managing VKA program, parallel measurements are conducted to compare point-of-care testing (POCT) INR with ...
Nikolaj Julian Skrøder Nytofte +1 more
doaj +2 more sources
Impact of thromboplastin reagents on monitoring INR in a patient with triple-positive antiphospholipid syndrome: a case report [PDF]
Frontiers in ImmunologyIntroductionAntiphospholipid syndrome (APS) is an autoimmune disease characterized by a hypercoagulable state and recurrent thromboembolism (TE). Patients with triple-positive antiphospholipid antibodies (APAs) are at the highest risk of TE.
Lóránt Varju +10 more
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Identifying the silent deficiency: Severe Factor XI deficiency in an asymptomatic patient with isolated prolonged activated partial thromboplastin time—A case report [PDF]
SAGE Open Medical Case ReportsAssessing a patient with a suspected bleeding disorder is a complex aspect of hematology. Prolonged activated partial thromboplastin time often indicates a coagulation factor deficiency or inhibitor and warrants detailed evaluation. Factor XI deficiency,
Awni Alshurafa +4 more
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A Novel Thromboplastin-Based Rat Model of Ischemic Stroke
Brain Sciences, 2021 The thromboembolic ischemia model is one of the most applicable for studying ischemic stroke in humans. The aim of this study was to develop a novel thromboembolic stroke model, allowing, by affordable tools, to reproduce cerebral infarction in rats.
Irina V. Ostrova +3 more
doaj +1 more source
The role of hemostatic changes in the pathogenesis of diabetic retinopathy
Journal of Education, Health and Sport, 2022 Introduction: The paper presents the results of the hemostasis system of rats with experimental diabetic retinopathy. Material and methods: Experimental studies were performed on white Wistar rats, which were divided into 2 groups: 1st group – intact
Nataliya Preys, Ivan Savytskyi
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Frontiers in Neurology, 2020 Background: Lupus anticoagulant (LA) owns procoagulant properties in vivo and prolongs phospholipid-dependent clotting times in vitro. The prolonged in vitro clotting time can be misinterpreted as a bleeding disorder.
Aydin Huseynov +10 more
doaj +1 more source
UMYU Journal of Microbiology Research, 2021 Coronavirus disease 2019 (COVID-19) is associated with coagulation abnormalities—disordered hemostasis and high thrombotic risk. The aim of the study was to compare and analyze the clotting profiles between COVID-19 and non-COVID-19 ...
Abdulfatai, K. +5 more
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Influence of vitamin K antagonist treatment on activated partial thromboplastin time [PDF]
, 2015 A
Devreese, Katrien +2 more
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Frontiers in Oncology, 2017 Tissue factor (TF)-expressing tumor-derived extracellular vesicles (EVs) can promote metastasis and pre-metastatic niche formation, but the mechanisms by which this occurs remain largely unknown. We hypothesized that generation of activated factor X (FXa)
Sara P. Y. Che +2 more
doaj +1 more source
Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]
, 2010 The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Braun, Jean-Pierre +5 more
core +1 more source