Results 191 to 200 of about 81,436 (246)
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Thrombosis and Haemostasis, 2013
Summary Dabigatran is an oral direct thrombin inhibitor that does not require routine laboratory monitoring. However, an assessment of its anticoagulant effect in certain clinical settings is desirable.
G. Hapgood +4 more
semanticscholar +1 more source
Summary Dabigatran is an oral direct thrombin inhibitor that does not require routine laboratory monitoring. However, an assessment of its anticoagulant effect in certain clinical settings is desirable.
G. Hapgood +4 more
semanticscholar +1 more source
Calibration of thromboplastins
Proceedings of the Royal Society of London. Series B: Biological Sciences, 1995Anticoagulant therapy with coumarin drugs requires tests on the patient's blood to determine the dose rate for the drug. The tests involve measuring the effect of a preparation of a certain reagent, thromboplastin, in accelerating the clotting of the patient's blood.
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International Journal of Laboratory Hematology, 2013
We report the effect of temperature and storage duration on a range of haematological analytes: activated partial thromboplastin time (APTT), D‐dimers, fibrinogen (Fbg), prothrombin time (PT) and thrombin time (TT).
Y. Zhao, G. Lv
semanticscholar +1 more source
We report the effect of temperature and storage duration on a range of haematological analytes: activated partial thromboplastin time (APTT), D‐dimers, fibrinogen (Fbg), prothrombin time (PT) and thrombin time (TT).
Y. Zhao, G. Lv
semanticscholar +1 more source
Thrombosis and Haemostasis, 1970
SummaryTissue thromboplastin is the key reagent in the one-stage prothrombin time test. To obtain reliable results, a potent thromboplastin with constant activity and stability is required. This need is met by acetone-dehydrated rabbit brain. This reagent, when protected against oxidation by sealing in an evacuated tube, retains its full activity ...
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SummaryTissue thromboplastin is the key reagent in the one-stage prothrombin time test. To obtain reliable results, a potent thromboplastin with constant activity and stability is required. This need is met by acetone-dehydrated rabbit brain. This reagent, when protected against oxidation by sealing in an evacuated tube, retains its full activity ...
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American Journal of Clinical Pathology, 1961
The partial thromboplastin time (PPT) test consists of recalcifying plasma in the presence of a lipid reagent that supplies optimal platelet thromboplastic factor-like activity.
Robert R. Proctor, S. Rapaport
semanticscholar +1 more source
The partial thromboplastin time (PPT) test consists of recalcifying plasma in the presence of a lipid reagent that supplies optimal platelet thromboplastic factor-like activity.
Robert R. Proctor, S. Rapaport
semanticscholar +1 more source
The Annals of Pharmacotherapy, 2012
Background: Patients receiving the direct thrombin inhibitor dabigatran may have selected anticoagulation assays performed as part of routine care. The effect of dabigatran on the international normalized ratio (INR), activated partial thromboplastin ...
William E Dager +3 more
semanticscholar +1 more source
Background: Patients receiving the direct thrombin inhibitor dabigatran may have selected anticoagulation assays performed as part of routine care. The effect of dabigatran on the international normalized ratio (INR), activated partial thromboplastin ...
William E Dager +3 more
semanticscholar +1 more source
Thromboplastin generation by saliva
Oral Surgery, Oral Medicine, Oral Pathology, 1962Abstract In order to determine directly whether saliva has any specific thromboplastic activity or whether its effect in accelerating blood coagulation is nonspecific, we compared saliva with commercial tissue thromboplastins in the following modified hematologic tests: 1. 1.
Richard G. Taylor, H.Chris Doku
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1984
A few years ago, a field trial was carried out in which a large number of plasma samples (100 normals, 806 anticoagulated patients, as well as patients with deficiencies of the factors II, V, VII and X) were tested with a newly developed rabbit brain thromboplastin (Thromboplastin FS) and with Human Brain Thromboplastin prepared by Prof.
R. Spaethe, I. Shirley
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A few years ago, a field trial was carried out in which a large number of plasma samples (100 normals, 806 anticoagulated patients, as well as patients with deficiencies of the factors II, V, VII and X) were tested with a newly developed rabbit brain thromboplastin (Thromboplastin FS) and with Human Brain Thromboplastin prepared by Prof.
R. Spaethe, I. Shirley
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The Annals of Pharmacotherapy, 2011
Background: Unfractionated heparin (UFH) has been used clinically for 5 decades. Despite being a cornerstone of anticoagulation, UFH is limited by its unpredictable pharmacokinetic profile, which makes close laboratory monitoring necessary.
David J. Guervil +5 more
semanticscholar +1 more source
Background: Unfractionated heparin (UFH) has been used clinically for 5 decades. Despite being a cornerstone of anticoagulation, UFH is limited by its unpredictable pharmacokinetic profile, which makes close laboratory monitoring necessary.
David J. Guervil +5 more
semanticscholar +1 more source
The thermolability of tissue thromboplastins
Irish Journal of Medical Science, 19661. The thermolability of tissue thromboplastins is markedly increased in the presence of cysteine, glutathione sulphite and hydrosulphite, but not in the presence of cysteine, ascorbate, thiosulphate or thiocyanate. 2. Thermostability is increased by fluoride (and ageing), but is overcome by cysteine. 3.
R. A. Q. O’Meara, W. A. Boggust
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