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Thromboplastin standards

Biologicals, 2010
The Prothrombin Time (PT) test is used for monitoring of treatment with Vitamin K-antagonists (VKA). The result of the PT test should be expressed as the International Normalized Ratio (INR). Calculation of INR is based on the availability of International Standards (IS) for thromboplastin and a calibration model. Calibration of a new PT test system is
A. M. van den Besselaar   +2 more
openaire   +4 more sources

Effects of sugammadex on activated partial thromboplastin time and prothrombin time in healthy subjects.

International journal of clinical pharmacology and therapeutics, 2014
OBJECTIVES To assess the impact of sugammadex on activated partial thromboplastin time (APTT) and international normalized ratio for prothrombin time (PT(INR)) in healthy subjects and characterize the concentration-dependency of sugammadex effects on ...
P. De Kam   +7 more
semanticscholar   +1 more source

The influence of free hemoglobin and bilirubin on heparin monitoring by activated partial thromboplastin time and anti-Xa assay.

Archives of Pathology & Laboratory Medicine, 2014
CONTEXT Elevated free hemoglobin (Hb) and bilirubinemia complicate extracorporeal membrane oxygenation and could affect unfractionated heparin (UH) therapy monitoring by anti-Xa assay and activated partial thromboplastin time (aPTT).
V. Kostousov   +3 more
semanticscholar   +1 more source

The Inactivation of Plasma-Thromboplastin

Thrombosis and Haemostasis, 1958
Summary1. Anti-plasmathromboplastin activity is found in plasma and in serum.2. The anti-plasmathromboplastin activity was increased in the majority of patients with hemophilia A and B, with chronic idiopathic thrombocytopenia, uremia, and in the cases of obstetrical afibrinogenemia, obstructive jaundice and Morbus Addison examined.
Deutsch E, Mammen E
openaire   +3 more sources

Calibration of thromboplastins

Proceedings of the Royal Society of London. Series B: Biological Sciences, 1995
Anticoagulant therapy with coumarin drugs requires tests on the patient's blood to determine the dose rate for the drug. The tests involve measuring the effect of a preparation of a certain reagent, thromboplastin, in accelerating the clotting of the patient's blood.
openaire   +3 more sources

Thromboplastin as a Reagent

Thrombosis and Haemostasis, 1970
SummaryTissue thromboplastin is the key reagent in the one-stage prothrombin time test. To obtain reliable results, a potent thromboplastin with constant activity and stability is required. This need is met by acetone-dehydrated rabbit brain. This reagent, when protected against oxidation by sealing in an evacuated tube, retains its full activity ...
openaire   +3 more sources

The partial thromboplastin time with kaolin. A simple screening test for first stage plasma clotting factor deficiencies.

American Journal of Clinical Pathology, 1961
The partial thromboplastin time (PPT) test consists of recalcifying plasma in the presence of a lipid reagent that supplies optimal platelet thromboplastic factor-like activity.
Robert R. Proctor, S. Rapaport
semanticscholar   +1 more source

Thromboplastin generation by saliva

Oral Surgery, Oral Medicine, Oral Pathology, 1962
Abstract In order to determine directly whether saliva has any specific thromboplastic activity or whether its effect in accelerating blood coagulation is nonspecific, we compared saliva with commercial tissue thromboplastins in the following modified hematologic tests: 1. 1.
Richard G. Taylor, H.Chris Doku
openaire   +3 more sources

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