Results 51 to 60 of about 116,300 (353)
Performance Evaluation of Four Activated Partial Thromboplastin Time Reagents
Pharmacology and Clinical Pharmacy Research, 2018 Activated Partial Thromboplastin Time (APTT) is a hematological examination to identify hemostatic abnormalities. This study aimed to compare the performance evaluation of four APTT reagents, i.e., CK Prest, Pathromtin SL, Actin SL, and Cephascreen.
Peppi Z. Yuzaqi +2 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
Saline obtaining and time standardization of prothrombin using thromboplastin of human placenta.
Medisur, 2003 Background: Determining prothombine ‘s time is an important lab test in the study of coagulation disorders. To develop this essay the main reactive was thromboplastin , a substance that is presented in tissue and that has been obtained habitually from ...
María de Jesús Sánchez Bouza +5 more
doaj +2 more sources
The Pan African Medical Journal, 2021 INTRODUCTION: von Willebrand Disease (vWD) is the most prevalent bleeding disorder. Women are more likely to manifest abnormal bleeding symptoms due to physiologic events and menorrhagia is the most common presenting symptom.
Miyoba Melinda Munsanje +6 more
doaj +1 more source
Advanced Science, EarlyView.Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang +6 more
wiley +1 more source
Evaluation of Antiphospholipid Antibodies and Activated Partial Thromboplastin Time in Women with Adverse Outcome of Pregnancy [PDF]
Iranian Journal of Medical Sciences, 2010 Adverse outcome of pregnancy is a potentially dangerouscomplication of conception and affects 15-20% of pregnancies.According to recent studies increased level of bloodantiphospholipids antibodies, if accompanied by predisposingfactors, can be an adverse
Sariyeh Golmahammad lou +4 more
doaj
The management of a blood donor bitten by a snake [PDF]
, 2017 The worldwide burden of snakebite is high and venomous snakes are found in many regions of the world and are a threat to public health. In Italy, for instance, viper bites are an infrequent but not negligible event.
Catalano, Liviana +5 more
core +1 more source
Challenges of modeling pristane‐induced lupus in non‐human primates
Animal Models and Experimental Medicine, EarlyView.Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova +5 more
wiley +1 more source
Revista do Colégio Brasileiro de Cirurgiões, 2018 RESUMO Objetivo: estudar a expressão do fator tecidual (FT) e sua correlação com o prognostico e sobrevida em pacientes com carcinoma gástrico. Métodos: verificamos a expressão imuno-histoquímica do FT em 50 espécimes de adenocarcinomas gástricos de ...
Marcelo Garcia Toneto +7 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro +3 more
wiley +1 more source