Results 71 to 80 of about 3,560 (171)

Correction of Thrombocytopenia with Thrombopoietin Receptor Agonists in Patients with Liver Cirrhosis Before Elective Surgery or Invasive Procedures

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to review the pathogenesis of thrombocytopenia and possible ways of its correction in patients with liver cirrhosis before elective surgical interventions or invasive procedures to optimize clinical practice.Key points.
T. A. Deeva, M. V. Maevskaya, V. T. Ivashkin   +2 more
doaj   +1 more source

Feasibility of romiplostim discontinuation in adult thrombopoietin-receptor agonist responsive patients with primary immune thrombocytopenia: an observational retrospective report in real life clinical practice

Hematology Reports, 2015
Thrombopoietin mimetics are new treatment options for patients with immune thrombocytopenia (ITP). Because of their mechanism of action, long-term administration was envisioned in order to maintain effective thrombopoiesis.
Monica Carpenedo, Silvia Cantoni, Veronica Coccini, Marilena Fedele, Enrica Morra, Enrico Maria Pogliani   +5 more
doaj   +1 more source

Efficacy and safety of high doses of eltrombopag for treating adult immune thrombocytopenia: Results from a multicentre retrospective cohort study

British Journal of Haematology, EarlyView.
Salomé Dahan, Stéphanie Guillet, Olivier Fain, Delphine Gobert, Stéphane Cheze, Florent Broca, Bertrand Godeau, Marc Michel   +7 more
wiley   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

Pharmacoeconomic analysis of thrombopoietin receptor agonists in the treatment of chronic idiopathic thrombocytopenic purpura in adults

Качественная клиническая практика, 2018
Actuallity. Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease caused by the production of antibodies to the platelet and megakaryocytes membrane structure, which causes to increase the platelet destruction, but also inadequate ...
E. A. Pyadushkina, M. Yu. Frolov, V. A. Shuvaev, V. A. Rogov   +3 more
doaj   +1 more source

Reconceptualizing Aplastic Anemia—Seed, Worm, Soil

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu, Zining Wang, Jiaming Hu, Chunyan Liu, Rong Fu   +4 more
wiley   +1 more source

Cancer treatment-induced thrombocytopenia: diagnosis, mechanisms and management

Frontiers in Immunology
Cancer treatment-induced thrombocytopenia (CTIT) is a common adverse effect in malignant tumor patients, significantly increasing the risk of bleeding and negatively impacting treatment efficacy and quality of life.
Xutong Zhao, Xiu Shan, Shaofeng Sui, Qinghao Song, Miao Cheng, Yi Zhao   +5 more
doaj   +1 more source

Avatrombopag in heavily pretreated chronic immune thrombocytopenia: a single center experience from Oman

Frontiers in Medicine
BackgroundChronic immune thrombocytopenia (ITP) is characterized by persistent thrombocytopenia and bleeding risk, and a subset of patients remains refractory or relapses despite multiple lines of therapy.
Nashwa Al-Sharji, Bushra Salman, Shireen Al-Zadjali, Mohammed Al-Huneini   +3 more
doaj   +1 more source

Total remission of severe immune thrombocytopenia after short term treatment with romiplostim

Hematology Reports, 2011
Immune thrombocytopenia (ITP) in adults is an acquired chronic immune-mediated disorder defined by isolated thrombocytopenia. In recent years, an improved understanding of the pathophysiology of ITP has been achieved and is now accepted that the disorder
Efthymia Vlachaki, Vaia Papageorgiou, Filippos Klonizakis, Maria Spandonidou, Sofia Chisan, Evaggelia Vetsiou, Elissavet Ioannidou   +6 more
doaj   +1 more source

Proposal of treatment algorithm for immune thromocytopenia in adult patients of a hematology service at a referral center in Northeastern Brazil

Hematology, Transfusion and Cell Therapy, 2019
Introduction: The management of adult (≥18 years) immune thrombocytopenia patients relies on platelet count, the risk of bleeding and presence of bleeding.
Rosângela de Albuquerque Ribeiro, Gentil Claudino de Galiza Neto, Amanda da Silva Furtado, Lucas Loiola Ponte Albuquerque Ribeiro, Marcela Sobreira Kubrusly, Elsie Sobreira Kubrusly   +5 more
doaj   +1 more source