Results 81 to 90 of about 1,394,911 (165)

Avatrombopag in heavily pretreated chronic immune thrombocytopenia: a single center experience from Oman

Frontiers in Medicine
BackgroundChronic immune thrombocytopenia (ITP) is characterized by persistent thrombocytopenia and bleeding risk, and a subset of patients remains refractory or relapses despite multiple lines of therapy.
Nashwa Al-Sharji, Bushra Salman, Shireen Al-Zadjali, Mohammed Al-Huneini   +3 more
doaj   +1 more source

Total remission of severe immune thrombocytopenia after short term treatment with romiplostim

Hematology Reports, 2011
Immune thrombocytopenia (ITP) in adults is an acquired chronic immune-mediated disorder defined by isolated thrombocytopenia. In recent years, an improved understanding of the pathophysiology of ITP has been achieved and is now accepted that the disorder
Efthymia Vlachaki, Vaia Papageorgiou, Filippos Klonizakis, Maria Spandonidou, Sofia Chisan, Evaggelia Vetsiou, Elissavet Ioannidou   +6 more
doaj   +1 more source

Efficacy and safety of thrombopoietin receptor agonists in the treatment of thrombocytopenia after hematopoietic stem cell transplantation: a meta-analysis and systematic review

, 2021
Thrombocytopenia is a tough complication after hematopoietic stem cell transplantation (HSCT) with elusive pathogenesis and lack of well-established therapies.
Yifang Yao (11776165), Yaqiong Tang (11776168), Xiaoyan Xu (283959), Xueqian Li (4863082), Rui Zhang (13940), JiaQian Qi (11776171), Tingting Pan (4735617), Yue Han (560788)   +7 more
core   +1 more source

Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis

Health Technology Assessment, 2020
Background: There have been no licensed treatment options in the UK for treating thrombocytopenia in people with chronic liver disease requiring surgery.
Nigel Armstrong, Nasuh Büyükkaramikli, Hannah Penton, Rob Riemsma, Pim Wetzelaer, Vanesa Huertas Carrera, Stephanie Swift, Thea Drachen, Heike Raatz, Steve Ryder, Dhwani Shah, Titas Buksnys, Gill Worthy, Steven Duffy, Maiwenn Al, Jos Kleijnen   +15 more
doaj   +1 more source

Enhanced thrombopoietin but not G-CSF receptor stimulation induces self-renewing hematopoietic stem cell divisions in vivo

, 2016
In steady-state adult hematopoiesis, most hematopoietic stem cells (HSCs) are in the resting phase of the cell cycle. Upon enhanced hematopoietic demand, HSCs can be induced to divide and self-renew or differentiate.
Takizawa, H, Kovtonyuk, L V, Manz, M G, Kovtonyuk LV, Manz MG, Takizawa H   +5 more
core   +1 more source

Proposal of treatment algorithm for immune thromocytopenia in adult patients of a hematology service at a referral center in Northeastern Brazil

Hematology, Transfusion and Cell Therapy, 2019
Introduction: The management of adult (≥18 years) immune thrombocytopenia patients relies on platelet count, the risk of bleeding and presence of bleeding.
Rosângela de Albuquerque Ribeiro, Gentil Claudino de Galiza Neto, Amanda da Silva Furtado, Lucas Loiola Ponte Albuquerque Ribeiro, Marcela Sobreira Kubrusly, Elsie Sobreira Kubrusly   +5 more
doaj   +1 more source

Thrombocytopenia and Procedural Prophylaxis in the Era of Thrombopoietin Receptor Agonists

Hepatology Communications, 2019
Thrombocytopenia is common in patients with advanced liver disease. These patients frequently require invasive diagnostic or therapeutic procedures in the setting of thrombocytopenia.
Kathy M. Nilles, Stephen H. Caldwell, Steven L. Flamm   +2 more
doaj   +1 more source

Genetic studies of familial myeloproliferative disorders [PDF]

, 2007
Hereditary thrombocythemia (HT) is an autosomal dominant disorder with clinical features resembling sporadic essential thrombocythemia. HT families share similar clinical symptoms caused by heterogeneous genetic alterations.
Liu, Kun
core   +1 more source

Hetrombopag for the treatment of chemotherapy-induced thrombocytopenia in patients with solid tumors

Research and Practice in Thrombosis and Haemostasis
Based on real-world research, we aimed to systematically evaluate the efficacy and safety of hetrombopag for the treatment of chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors.
Yuan Liu, Bo Liu, Shan-Shan Fang, Run-Sheng Zhao, Lin Li, Hui-Xiong Qi, Quan Li   +6 more
doaj   +1 more source

Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two cases and review of the literature

Frontiers in Cardiovascular Medicine
IntroductionPrimary immune thrombocytopenia is an autoimmune bleeding disorder characterized by variable immune-mediated platelet destruction. These patients have reported thrombotic complications, both venous and arterial, in addition to bleeding ...
Roberto Castelli, Enrico Atzori, Alessandro Palmerio Delitala, Salvatore Antonio Masala, Valentina Micheluzzi, Enrico Ponti, Enrico Ponti, Giuseppe Sanna, Dante Castro, Antonio Gidaro, Mattia Donadoni, Roberto Manetti, Pierluigi Merella, Nicia Isabella Profili, Andrea Maria D'Armini, Gavino Casu, Gavino Casu   +16 more
doaj   +1 more source