Results 81 to 90 of about 3,560 (171)

Thrombopoietin-receptor agonists in haematological disorders: The Danish experience

Platelets, 2011
The objective of this study was to investigate the use of thrombopoietin-receptor agonists (TPO-ra) in patients with refractory primary immune thrombocytopenia (ITP) as well as off-label use of TPO-ra in Danish haematology departments. Hospital medical records from 32 of the 39 patients having received TPO-ra from 2009 to 1 May 2011 were available for ...
Gudbrandsdottir, S., Hasselbalch, H., Frederiksen, H.   +2 more
openaire   +3 more sources

Pragmatic Clinical Trial of Fostamatinib as Second‐Line Therapy in Adult Patients With Immune Thrombocytopenia and Insufficient Response to Prior Therapy: The Fostamatinib FORTE Trial

eJHaem, Volume 7, Issue 4, August 2026.
Amber Afzal, Robert Kribs, Sumit Sawhney, Mohit Narang, Frances Blevins, Robert Numerof, Francois Di Trapani, Sherry Ladha, Ruchika Goel   +8 more
wiley   +1 more source

Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis

Health Technology Assessment, 2020
Background: There have been no licensed treatment options in the UK for treating thrombocytopenia in people with chronic liver disease requiring surgery.
Nigel Armstrong, Nasuh Büyükkaramikli, Hannah Penton, Rob Riemsma, Pim Wetzelaer, Vanesa Huertas Carrera, Stephanie Swift, Thea Drachen, Heike Raatz, Steve Ryder, Dhwani Shah, Titas Buksnys, Gill Worthy, Steven Duffy, Maiwenn Al, Jos Kleijnen   +15 more
doaj   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
Stephanie Juané Kennedy
wiley   +1 more source

Thrombocytopenia and Procedural Prophylaxis in the Era of Thrombopoietin Receptor Agonists

Hepatology Communications, 2019
Thrombocytopenia is common in patients with advanced liver disease. These patients frequently require invasive diagnostic or therapeutic procedures in the setting of thrombocytopenia.
Kathy M. Nilles, Stephen H. Caldwell, Steven L. Flamm   +2 more
doaj   +1 more source

Novel Perspectives on Thrombopoietin Receptor Agonists Applications

Hämostaseologie
Abstract Second-generation thrombopoietin receptor agonists (TPO-RAs), romiplostim, eltrombopag, and avatrombopag, have been proved to be significant stimulators of megakaryopoiesis and, in the last decade, they have been incorporated in the treatment options against refractory immune thrombocytopenia in children and adults that do ...
Stafylidis, Christos, Vlachopoulou, Dimitra, Syriopoulou, Stavroula, Chatzidavid, Sevastianos, Viniou, Nora-Athina   +4 more
openaire   +3 more sources

Hetrombopag for the treatment of chemotherapy-induced thrombocytopenia in patients with solid tumors

Research and Practice in Thrombosis and Haemostasis
Based on real-world research, we aimed to systematically evaluate the efficacy and safety of hetrombopag for the treatment of chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors.
Yuan Liu, Bo Liu, Shan-Shan Fang, Run-Sheng Zhao, Lin Li, Hui-Xiong Qi, Quan Li   +6 more
doaj   +1 more source

Repurposing the thrombopoietin receptor agonist eltrombopag as an anticryptococcal agent

Medical Mycology, 2019
AbstractIn this study, a Food and Drug Administration (FDA)-approved drug with previously unreported antifungal activity was investigated for suitability for use as an anticryptococcal agent. First, we screened a compound library of 1018 FDA-approved drugs against Cryptococcus neoformans.
Ying-Lien Chen, Sheng-Yung Yang, Li-Hang Hsu, Hao-Tai Ko   +3 more
openaire   +3 more sources

Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two cases and review of the literature

Frontiers in Cardiovascular Medicine
IntroductionPrimary immune thrombocytopenia is an autoimmune bleeding disorder characterized by variable immune-mediated platelet destruction. These patients have reported thrombotic complications, both venous and arterial, in addition to bleeding ...
Roberto Castelli, Enrico Atzori, Alessandro Palmerio Delitala, Salvatore Antonio Masala, Valentina Micheluzzi, Enrico Ponti, Enrico Ponti, Giuseppe Sanna, Dante Castro, Antonio Gidaro, Mattia Donadoni, Roberto Manetti, Pierluigi Merella, Nicia Isabella Profili, Andrea Maria D'Armini, Gavino Casu, Gavino Casu   +16 more
doaj   +1 more source

Haemostatic imbalance in a patient with psoriasis

Journal of Clinical and Scientific Research
Psoriasis is a chronic immune-mediated inflammatory skin disease that if left untreated, can impair most of the systems, especially the haemostatic system.
Sasidharan Athira, Rafi Aboobacker Mohamed   +1 more
doaj   +1 more source