Results 121 to 130 of about 999,924 (367)

Cancer and thrombosis: Managing the risks and approaches to thromboprophylaxis [PDF]

, 2006
Patients with cancer are at increased risk of venous thromboembolism (VTE) compared with patients without cancer. This results from both the prothrombotic effects of the cancer itself and iatrogenic factors, such as chemotherapy, radiotherapy, indwelling
Altinbas M, Athanasoulis CA, Bergqvist D, Bergqvist D, Buller HR, Clagett PG, Da Silva MS, Decousus H, ENOXACAN Study Group, Falanga A, Geerts WH, Gitter MJ, Goldenberg N, Gomes MPV, Green D, Haas S, Heit JA, Hettiarachchi RJK, Hull R, Hutten BA, International Multicentre Trial, Johnson MJ, Kakkar VV, Karthaus M, Koopman MMW, Levine MN, Mousa S A, Mousa SA, Prandoni P, Rasmussen MS, Rickles FR, Sallah S, Samama M, Siragusa B, The Columbus Investigators, White RH, Zacharski LR   +36 more
core   +1 more source

Modelling pulsatile blood flow through surgically coupled microvascular anastomoses [PDF]

arXiv, 2018
The significant rates of post-operative arterial thrombus formation following the sutured anastomosis (surgical connection) of vessels in microvascular reconstruction has kindled the development of engineered solutions such as the UNILINK coupler. These devices reduce thrombosis rates, which recent numerical studies suggest to be due to decreases in ...
arxiv  

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source

A horse, a horse, my kingdom for a horse. Saddle thrombosis of carotid bifurcation in acute stroke [PDF]

, 2012
Background: Saddle thrombosis is less frequently detected in carotid arteries than in peripheral arterial embolism. The clot and the distal vessel patency have to be promptly recognized in these cases, because if the carotid vessel is open distally ...
DI PIERO, Vittorio, Edoardo Vicenzini, GIANNONI, Maria Fabrizia, LENZI, Gian Luigi, Maria Chiara Ricciardi, SIRIMARCO, GAIA, TOSCANO M.   +6 more
core   +1 more source

Mechanochemistry: Fundamental Principles and Applications

Advanced Science, EarlyView.
In this review, the physicochemical principles of mechanochemistry are first clarified. Based on this foundation, the research basis and cutting‐edge scientific achievements in four areas are introduced: solid‐state organic chemistry, polymers, interface science, and biomechanochemistry.
Liang Dong, Luofei Li, Huiyan Chen, Yi Cao, Hai Lei   +4 more
wiley   +1 more source

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter, Alexis A. Thompson, Francis J. Pierciey Jr, Matthew Hsieh, Naoya Uchida, Philippe Leboulch, Manfred Schmidt, Melissa Bonner, Ruiting Guo, Alex Miller, Jean‐Antoine Ribeil, David Davidson, Mohammed Asmal, Mark C. Walters, John F. Tisdale   +14 more
wiley   +1 more source

Sepsis and obesity: a scoping review of diet-induced obesity murine models

Intensive Care Medicine Experimental
Background Sepsis, the life-threatening host response to infection, is a major cause of mortality. Obesity increases vulnerability to sepsis; however, some degree of obesity may be protective, called the “obesity paradox”.
Mikaela Eng, Keshikaa Suthaaharan, Logan Newton, Fatima Sheikh, Alison Fox-Robichaud, the National Preclinical Sepsis Platform, Sepsis Canada   +5 more
doaj   +1 more source

Transport of platelets induced by red blood cells based on mixture theory [PDF]

arXiv, 2017
Thrombosis is a common complication following the surgical implantation of blood contacting devices, and is strongly influenced by the phenomenon of near-wall enrichment of platelets. This paper describes a multi-constituent continuum approach to study this phenomenon.
arxiv  

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

Romiplostim use in pregnant women with immune thrombocytopenia

American Journal of Hematology, Volume 98, Issue 1, Page 31-40, January 2023., 2023
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel, Nichola Cooper, Tatiana Lawrence, Marc Michel, Emilie Vander Haar, Kejia Wang, Hongmei Wang, Hossam Saad   +7 more
wiley   +1 more source