Results 281 to 290 of about 523,717 (316)
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Journal of Cardiovascular Pharmacology, 1995
Cytokines are pleiotropic mediators of inflammation and immunity. Leukocytes and vascular cells are both sources of cytokines and targets for them. Several cytokines affect key functions of vascular wall cells. Several clinical acute or chronic inflammatory situations associate modifications of the cytokine network and a prothrombotic state.
C, Dosquet, D, Weill, J L, Wautier
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Cytokines are pleiotropic mediators of inflammation and immunity. Leukocytes and vascular cells are both sources of cytokines and targets for them. Several cytokines affect key functions of vascular wall cells. Several clinical acute or chronic inflammatory situations associate modifications of the cytokine network and a prothrombotic state.
C, Dosquet, D, Weill, J L, Wautier
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Annals of Internal Medicine, 1966
Excerpt The characteristics of thrombi, in particular arterial thrombi, were delineated during the latter part of the nine-teenth century.
M F, Glynn, E A, Murphy, J F, Mustard
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Excerpt The characteristics of thrombi, in particular arterial thrombi, were delineated during the latter part of the nine-teenth century.
M F, Glynn, E A, Murphy, J F, Mustard
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Neurosurgery Clinics of North America
Effective anticoagulation management is crucial for balancing thromboembolism and hemorrhage risks in patients with traumatic brain injury (TBI) and spinal cord injury (SCI). A systematic review from January 1984 to August 2024 highlights a growing preference for prothrombin complex concentrate (PCC) as the primary reversal agent, with limited evidence
Marzia, Savi, Gregory, Hawryluk
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Effective anticoagulation management is crucial for balancing thromboembolism and hemorrhage risks in patients with traumatic brain injury (TBI) and spinal cord injury (SCI). A systematic review from January 1984 to August 2024 highlights a growing preference for prothrombin complex concentrate (PCC) as the primary reversal agent, with limited evidence
Marzia, Savi, Gregory, Hawryluk
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Seminars in Thrombosis and Hemostasis, 2017
AbstractThe most dreaded complication with percutaneous coronary intervention with stents, either bare-metal or drug-eluting stents is stent thrombosis (ST) and it has a significant detrimental effect on the outcome for the patient. The initial attempts at intervention with bare-metal stents had much higher rates of ST compared with what is currently ...
Mukesh, Gopalakrishnan, Amir S, Lotfi
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AbstractThe most dreaded complication with percutaneous coronary intervention with stents, either bare-metal or drug-eluting stents is stent thrombosis (ST) and it has a significant detrimental effect on the outcome for the patient. The initial attempts at intervention with bare-metal stents had much higher rates of ST compared with what is currently ...
Mukesh, Gopalakrishnan, Amir S, Lotfi
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Pharmacogenomics in Thrombosis
2010Inherited or acquired genetic abnormalities play a major role in thromboembolic complications. The goal of pharmacogenomics is to tailor medications to an individual's genetic makeup in order to improve the benefit-to-risk ratio. Significant findings have been documented showing the effect of certain genetic variations (e.g., in CYP2C9 and VKORC1) on ...
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Phlebology: The Journal of Venous Disease, 2012
The devastating consequences of venous thromboembolism have forever provided the impetus to explore safe and effective treatment strategies. To date, the pathophysiology and mechanism of thrombosis have been extensively studied and details of new thrombophilic conditions are continually being discovered.
T, Sarvananthan, S, Das
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The devastating consequences of venous thromboembolism have forever provided the impetus to explore safe and effective treatment strategies. To date, the pathophysiology and mechanism of thrombosis have been extensively studied and details of new thrombophilic conditions are continually being discovered.
T, Sarvananthan, S, Das
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Best Practice & Research Clinical Haematology, 1999
The fibrinolytic system generates plasmin, which dissolves fibrin in haemostatic plugs and in thrombi. It is often regarded simply as a secondary phenomenon responsive to the generation of thrombi but it is, rather, in dynamic balance with fibrin formation, such that abnormalities in either can lead to thrombosis.
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The fibrinolytic system generates plasmin, which dissolves fibrin in haemostatic plugs and in thrombi. It is often regarded simply as a secondary phenomenon responsive to the generation of thrombi but it is, rather, in dynamic balance with fibrin formation, such that abnormalities in either can lead to thrombosis.
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Human Pathology, 1987
Abnormal hemostasis is a fundamental property of malignant disease, not merely an epiphenomenon attributable to therapy or to chronic illness. Many types of tumor cells express clotting initiators such as tissue factor and act again late in the coagulation pathway by providing a surface for prothrombinase generation. Thus, entry of tumor cells into the
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Abnormal hemostasis is a fundamental property of malignant disease, not merely an epiphenomenon attributable to therapy or to chronic illness. Many types of tumor cells express clotting initiators such as tissue factor and act again late in the coagulation pathway by providing a surface for prothrombinase generation. Thus, entry of tumor cells into the
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