Results 61 to 70 of about 775,077 (341)
Scientific ReportsBone and bone-marrow (BM) have the same blood supply and thus may be considered as one organ. We previously demonstrated that the microcirculation hemostatic balance that includes heparanase, tissue factor (TF), TF pathway inhibitor (TFPI) and TFPI-2 are
Keren Asayag +6 more
doaj +1 more source
Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation
Scientific Reports, 2017 Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved.
Klytaimnistra Kiouptsi +5 more
doaj +1 more source
Dabigatran Plasma Measurement to Guide the Management of Acute Bleeding and Thrombotic Complications
European Journal of Case Reports in Internal Medicine, 2018 Oral anticoagulant therapy is recommended for the prevention and treatment of venous thromboembolism and to prevent stroke in non-valvular atrial fibrillation.
Maurizio Tala +6 more
doaj +1 more source
Coexisting Cardiac and Hematologic Disorders. [PDF]
, 2016 Patients with concomitant cardiac and hematologic disorders presenting for noncardiac surgery are challenging. Anemic patients with cardiac disease should be approached in a methodical fashion.
Goldhammer, Jordan E., Kohl, Benjamin A.
core +3 more sources
Blood, 2018 In this issue of Blood, Pilli and colleagues1 report that the essential antithrombotic factor protein S is inversely regulated by the transcription factor hypoxia inducible factor 1 (HIF1). This is an important contribution to our understanding of the molecular basis of the augmentation of thrombosis by hypoxia.
openaire +3 more sources
Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy
Advanced Functional Materials, EarlyView.Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi +6 more
wiley +1 more source
False-negative upper extremity ultrasound in the initial evaluation of patients with suspected subclavian vein thrombosis due to thoracic outlet syndrome (Paget-Schroetter syndrome) [PDF]
, 2020 OBJECTIVE: To assess the utilization and consequences of upper extremity Duplex ultrasound in the initial diagnostic evaluation of patients with suspected subclavian vein (SCV) thrombosis and venous thoracic outlet syndrome (VTOS).
Abuirqeba, Ahmmad A +4 more
core +1 more source
Risk marker associations with venous thrombotic events: a cross-sectional analysis. [PDF]
, 2014 ObjectiveTo examine the interrelations among, and risk marker associations for, superficial and deep venous events-superficial venous thrombosis (SVT), deep venous thrombosis (DVT) and pulmonary embolism (PE).DesignCross-sectional analysis.SettingSan ...
Chan, Virginia T +4 more
core +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
Frontiers in Molecular BiosciencesThrombosis is a major cause of morbidity and mortality worldwide, with a complex and multifactorial pathogenesis. Recent studies have shown that SIRT1, a member of the sirtuin family of NAD + -dependent deacetylases, plays a crucial role in regulating thrombosis, modulating key pathways including endothelial activation, platelet aggregation, and ...
Bettiol, Alessandra +11 more
openaire +3 more sources