Results 101 to 110 of about 116,907 (303)

Analysis of Late Complications Associated With Hematopoietic Stem Cell Transplantation in Patients With Dyskeratosis Congenita

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Dyskeratosis congenita (DKC) is a genetic disorder frequently complicated by bone marrow failure (BMF). Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment option for BMF in DKC. However, late complications of DKC, especially pulmonary fibrosis (PF), pose significant challenges.
Takashi Koike, Shohei Yamamoto, Mayuko Shibata, Kohei Otsuka, Yumiko Sugishita, Ryota Kaneko, Naoko Kawabata, Sachio Fujita, Kosuke Akiyama, Daisuke Toyama, Miharu Yabe, Atsushi Uchiyama, Hiromasa Yabe   +12 more
wiley   +1 more source

Complement as the enabler of carfilzomib‐induced thrombotic microangiopathy

British Journal of Haematology, 2020
Carfilzomib has been associated with the development of thrombotic microangiopathy (TMA) in relapsed/refractory multiple myeloma patients, a severe disease with no currently available aetiological treatment.
M. Blasco, A. Martínez-Roca, L. Rodríguez-Lobato, A. García-Herrera, L. Rosiñol, P. Castro, S. Fernandez, L. Quintana, M. Cibeira, J. Bladé, C. Fernández de Larrea, N. Tovar, R. Jimenez, E. Poch, E. Guillen, J. Campistol, E. Carreras, M. Díaz-Ricart, M. Palomo   +18 more
semanticscholar   +1 more source

Clinical effects of combination therapy with continuous renal replacement therapy and continuous intravenous sodium infusion therapy

Therapeutic Apheresis and Dialysis, Volume 29, Issue 4, Page 543-556, August 2025.
Abstract Introduction This single‐center retrospective study investigated the clinical effects of combination therapy involving continuous renal replacement therapy (CRRT) and continuous intravenous sodium infusion therapy (cIVNa) in critically ill patients with prerenal acute kidney injury (AKI) who were expected to experience insufficient plasma ...
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +5 more
wiley   +1 more source

Characterization of the complications associated with plasma exchange for thrombotic thrombocytopaenic purpura and related thrombotic microangiopathic anaemias: a single institution experience. [PDF]

, 2014
Plasma exchange (PEX) is a life-saving therapeutic procedure in patients with thrombotic thrombocytopaenic purpura (TTP) and other thrombotic microangiopathic anaemias (TMAs). However, it may be associated with significant complications, exacerbating the
Collier, D, Leverett, D, McGuckin, S, Scully, M, Webster, H, Westwood, JP   +5 more
core   +2 more sources

An Update in Drug-Induced Thrombotic Microangiopathy

Frontiers in Medicine, 2020
Drug-induced thrombotic microangiopathy (DITMA) is a life-threatening complication that is often under-recognized and under-reported (1). Despite recent systematic reviews published in 2015 (2) and 2018 (3), the list of drugs implicated in TMA continues ...
T. Chatzikonstantinou, M. Gavriilaki, A. Anagnostopoulos, E. Gavriilaki   +3 more
semanticscholar   +1 more source

Severe Vitamin B12 Deficiency in Pregnancy Mimicking HELLP Syndrome

Case Reports in Obstetrics and Gynecology, 2019
Severe vitamin B12 deficiency may present with hematologic abnormalities that mimic thrombotic microangiopathy disorders such as hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. We report a patient diagnosed with severe vitamin
Shravya Govindappagari, Michelle Nguyen, Megha Gupta, Ramy M. Hanna, Richard M. Burwick   +4 more
doaj   +1 more source

Case of catastrophic antiphospholipid syndrome presenting as neuroretinitis and vaso-occlusive retinopathy

BMC Ophthalmology, 2020
Background Ocular involvement in catastrophic antiphospholipid syndrome (CAPS), a rare, life-threatening form of antiphospholipid syndrome (APS) that results in multiorgan failure and a high mortality rate, has rarely been reported.
Young In Yun, Ji Hyun Kim, Seon Hee Lim, Yo Han Ahn, Hee Gyung Kang, Il-Soo Ha, Baek-Lok Oh   +6 more
doaj   +1 more source

Case Report: Hematopoietic Stem Cell Transplantation to Treat Severe Acquired Aplastic Anemia in a Pediatric Kidney Transplant Recipient

Pediatric Transplantation, Volume 29, Issue 5, August 2025.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė, Goda Elizabeta Vaitkevičienė, Karolis Ažukaitis, Augustina Jankauskienė, Jelena Rascon   +4 more
wiley   +1 more source

Blood and Marrow Transplant Clinical Trials Network Toxicity Committee Consensus Summary: Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation [PDF]

, 2005
The syndrome of microangiopathic hemolysis associated with renal failure, neurologic impairment, or both is a recognized complication of hematopoietic stem cell transplantation.
Adams, Roberta, Carter, Shelly, Cutler, Corey, Ferrara, James, Giralt, Sergio, Ho, Vincent T., Horowitz, Mary, Martin, Paul, Soiffer, Robert   +8 more
core   +1 more source

Thrombotic microangiopathies: An update [PDF]

Hematology, 2006
Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by hemolytic anemia caused by fragmentation of erythrocytes and thrombocytopenia due to increased platelet aggregation and thrombus formation, eventually leading to disturbed microcirculation with reduced organ perfusion.
openaire   +2 more sources