Results 111 to 120 of about 116,907 (303)

Thrombotic microangiopathy after traumatic brain injury: A case report and review of the literature

Clinical Case Reports, 2023
Key Clinical Message This case report supports that trauma can rarely cause thrombotic microangiopathy (TMA). Early recognition is important due to a high mortality of untreated TMA, but diagnosis can be delayed by attributing lab abnormalities as due to
Xavier Van Meerbeeck, Leen Janssen, Rowena Vleut, Philip Verdonck, Alain Gadisseur, Rudi De Paep, Walter Verbrugghe, Philippe Jorens   +7 more
doaj   +1 more source

Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]

, 2016
Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core   +2 more sources

Complement activation in thrombotic microangiopathy [PDF]

Hämostaseologie, 2013
SummaryThe endothelium lining the vascular lumen is continuously exposed to complement from the circulation. When erroneously activated on host cells, complement may generate a deleterious effect on the vascular wall leading to endothelial injury, exposure of the subendothelial matrix and platelet activation.In this review the contribution of ...
Karpman, Diana, Tati, Ramesh
openaire   +4 more sources

Association of thrombotic microangiopathy with interferon therapy for hepatitis B: a case report

Journal of Medical Case Reports
Background Thrombotic microangiopathy is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ injury. The pathological features include vascular damage that is manifested by arteriolar and capillary thrombosis with ...
Shan Wei, Wenjuan Mei, Ying Wang
doaj   +1 more source

Innovative Use of Fostamatinib in Managing Refractory Immune Thrombocytopenia in an HIV‐Positive Patient: A Case Report

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Managing immune thrombocytopenia (ITP) in HIV patients remains challenging due to refractory cases and treatment limitations. This report highlights fostamatinib as a safe, effective, and antiretroviral therapy‐compatible option, offering durable platelet stabilization in a difficult‐to‐treat population.
Matteo Bellia, Riccardo Moia, Mattia Schipani, Carola Sella, Mariangela Greco, Wael Al Essa, Abdurraouf Mokhtar Mahmoud, Gianluca Gaidano, Andrea Patriarca   +8 more
wiley   +1 more source

Clinical case of thrombotic microangiopathy in obstetric practice

Сеченовский вестник, 2017
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
M. N. Mochalova, T. E. Belokrinitskaya, T. V. Haven, E. M. Shifman, K. G. Shapovalov, S. V. Kostromitin   +5 more
doaj  

The Efficacy and Safety of the Addition of Mitoxantrone Hydrochloride Liposome in Conditioning Regimen for High‐Risk Acute Myeloid Leukemia

Hematological Oncology, Volume 43, Issue 4, July 2025.
ABSTRACT Despite allo‐HSCT being the primary curative treatment for high‐risk AML, relapse‐free survival (RFS) remains suboptimal due to high relapse incidence. Our research focuses on optimizing the conditioning regimen by incorporating Mitoxantrone Hydrochloride Liposome (Lipo‐MIT), a novel nano‐formulation with enhanced pharmacokinetic properties ...
Xiaoyu Zhang, Donglin Yang, Aiming Pang, Sizhou Feng, Mingzhe Han, Yi He, Erlie Jiang   +6 more
wiley   +1 more source

Frequency and Significance of HIV Infection among Patients Diagnosed with Thrombotic Thrombocytopenic Purpura [PDF]

, 2017
Background. Case series of patients with a diagnosis of thrombotic thrombocytopenic purpura (TTP) have reported different frequencies of human immunodeficiency virus (HIV) infection; some series suggest that HIV infection may cause TTP. Methods.
Benjamin, Melody, Dezube, Bruce J., George, James N., Kremer Hovinga, Johanna A., Lämmle, Bernhard, Terrell, Deirdra R., Vesely, Sara K., Voskuhl, Gene W.   +7 more
core  

The global aHUS registry: methodology and initial patient characteristics [PDF]

, 2015
Background: Atypical hemolytic uremic syndrome (aHUS) is a rare, genetically-mediated systemic disease most often caused by chronic, uncontrolled complement activation that leads to systemic thrombotic microangiopathy (TMA) and renal and other end-organ ...
Ardissino, Gianluigi, Ariceta, Gema, Cohen, David, Cole, J. Alexander, Frémeaux-Bacchi, Véronique, Gasteyger, Christoph, Greenbaum, Larry A., Johnson, Sally, Licht, Christoph, Ogawa, Masayo, Schaefer, Franz, Vande Walle, Johan   +11 more
core   +2 more sources

A systematic review of the role of eculizumab in systemic lupus erythematosus-associated thrombotic microangiopathy

BMC Nephrology, 2020
Background Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated ...
R. Wright, Fariba Bannerman, M. Beresford, L. Oni   +3 more
semanticscholar   +1 more source