Results 131 to 140 of about 131,342 (265)

A patient with SLE-associated thrombotic microangiopathy and non-neutralizing antibodies against ADAMTS13 [PDF]

, 2017
In this case report, we describe for the first time a patient with thrombotic thrombocytopaenic purpura (TTP) accompanying highly active systemic lupus erythematosus (SLE) that was associated with non-neutralizing antibodies against the plasma ...
Ferrari, Silvia, Knecht, Margrith E., Mayr, Michael, Scheiflinger, Friedrich, Trendelenburg, Marten   +4 more
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Primary Thrombotic Microangiopathy in Pediatric Patients

Global Pediatric Health
Background . Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli , atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Methodology .
Andrés David Aranzazu Ceballos MD, Lina María Martínez Sánchez MSc, Ana Paulina Pamplona Sierra MD, Daniela Vergara Yánez MD, Liliana Franco Hincapié PhD, Richard Baquero Rodriguez MD   +5 more
doaj   +1 more source

SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins

Emerging Microbes and Infections
Complement hyperactivation and thrombotic microangiopathy are closely associated with severe COVID-19. Endothelial dysfunction is a key mechanism underlying thrombotic microangiopathy.
Jian Wu, Sanpeng Xu, Zhiqing Li, Boyi Cong, Zongheng Yang, Zhichao Yang, Wanfeng Gao, Shuo Liu, Zhou Yu, Sheng Xu, Nan Li, Jin Hou, Guoping Wang, Xuetao Cao, Shuxun Liu   +14 more
doaj   +1 more source

Everolimus-Associated Thrombotic Microangiopathy and Acute Kidney Injury in a Patient with Breast Cancer

Turkish Journal of Nephrology, 2019
Thrombotic microangiopathy is a pathological condition caused by several factors including drugs, and characterized by endothelial injury and small vessel occlusion. It may cause severe acute kidney injury.
Sibel ERSAN, Ahmet PEKER, Semih GÜLLE, Banu YILMAZ AVCIOĞLU   +3 more
doaj  

Case Report: Avermectin poisoning-associated hemolytic uremic syndrome

Frontiers in Immunology
Avermectin, a commonly used agricultural pesticide and antiparasitic agent, typically causes acute human toxicity characterized by central nervous system depression and gastrointestinal disturbances.
Jianping Xiao, Rui Shi, Qi Cao, Deguang Wang, Ruifeng Wang   +4 more
doaj   +1 more source

Clinical Dilemma in the Treatment of a Patient with Microangiopathic Haemolytic Anaemia, Thrombocytopaenia and Severe Hypertension [PDF]

, 2010
While haemolytic uraemic syndrome in children is predominantly associated with Shiga toxin -producing Escherichia coli (typically 0157:H7), some cases occur without associated diarrhoea, or as the manifestation of an underlying disorder other than ...
Castro, I, Gomes, D, Viegas, V
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Atypical haemolytic-uraemic syndrome caused by factor H mutation: case report and new management strategies in children [PDF]

, 2012
Atypical haemolytic uraemic syndrome is causedby alternative complement pathway dysregulation. It has recently been recognised that most cases are due to genetic factors and a growing list of mutations has been described.
Araújo, L., Barbot, J., Costa, T., Faria, M., Mota, C., Rocha, L.   +5 more
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Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
,, Goodship, Tim H J, Machin, Sam, Taylor, C Mark, Wigmore, Stephen J   +4 more
core   +1 more source

Thrombotic microangiopathy associated with use of interferon-beta

International Journal of Nephrology and Renovascular Disease, 2012
Teresa Olea,1 Raquel Díaz-Mancebo,1 Maria-Luz Picazo,2 Jorge Martínez-Ara,1 Angel Robles,3 Rafael Selgas,11Departments of Nephrology, 2Pathology, 3Internal Medicine, Hospital Universitario La Paz, Madrid, SpainAbstract: Interferon ...
Robles A, Martinez-Ara J, Picazo ML, Diaz-Mancebo R, Olea T, Selgas R   +5 more
doaj  

Evolution of biological agents: how established drugs can become less safe [PDF]

, 2017
Casadevall, Nicole, Flossmann, Oliver, Hunt, David   +2 more
core   +1 more source