Results 151 to 160 of about 17,452 (202)
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New England Journal of Medicine, 2002
The thrombotic microangiopathies (TMA) are a group of diseases associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction. These seemingly disparate entities share in common a pathogenic mechanism involving endothelial injury and thrombus formation.
Daniel, Halevy +3 more
+7 more sources
The thrombotic microangiopathies (TMA) are a group of diseases associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction. These seemingly disparate entities share in common a pathogenic mechanism involving endothelial injury and thrombus formation.
Daniel, Halevy +3 more
+7 more sources
Transfusion and Apheresis Science, 2011
Thrombotic microangiopathy (TMA) is a histopathological feature of various diseases including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). There are many secondary causes of TMA, many of them could mimic TTP or HUS. This article presents a short overview on TMA.
M, Mörtzell +18 more
openaire +2 more sources
Thrombotic microangiopathy (TMA) is a histopathological feature of various diseases including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). There are many secondary causes of TMA, many of them could mimic TTP or HUS. This article presents a short overview on TMA.
M, Mörtzell +18 more
openaire +2 more sources
European Journal of Internal Medicine, 2000
The term 'thrombotic microangiopathy' (TMA) describes syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation. The term 'hemolytic uremic syndrome' (HUS) has entered clinical use to describe childhood cases of TMA dominated by renal impairment, while ...
, Pisoni, , Remuzzi
openaire +2 more sources
The term 'thrombotic microangiopathy' (TMA) describes syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation. The term 'hemolytic uremic syndrome' (HUS) has entered clinical use to describe childhood cases of TMA dominated by renal impairment, while ...
, Pisoni, , Remuzzi
openaire +2 more sources
A case of thrombotic microangiopathy/microangiopathies
Blood Coagulation & Fibrinolysis, 2014We report a case of Streptococcus pneumonia sepsis-associated disseminated intravascular coagulation (DIC) with features of acute renal failure and microvascular thrombosis characterized by skin purpura and bilateral foot necrosis. The persistence of laboratory features of microangiopathic hemolytic anemia despite aggressive correction of DIC ...
Zhineng J, Yang +2 more
openaire +2 more sources
Emergency Medicine Clinics of North America
Thrombotic microangiopathies (TMAs) are rare diseases characterized by endothelial injury and microvascular clots. TMAs often lead to microangiopathic hemolytic anemia, thrombocytopenia, and end organ damage. Common TMA types include thrombotic thrombocytopenic purpura (TTP), infection-associated hemolytic uremic syndrome, and complement-mediated TMAs.
Ramy, Hanna +2 more
openaire +2 more sources
Thrombotic microangiopathies (TMAs) are rare diseases characterized by endothelial injury and microvascular clots. TMAs often lead to microangiopathic hemolytic anemia, thrombocytopenia, and end organ damage. Common TMA types include thrombotic thrombocytopenic purpura (TTP), infection-associated hemolytic uremic syndrome, and complement-mediated TMAs.
Ramy, Hanna +2 more
openaire +2 more sources
Seminars in Arthritis and Rheumatism, 2014
To review the clinical features and pathophysiologic mechanisms of the thrombotic microangiopathies (TMAs) including acquired and congenital thrombotic thrombocytopenic purpura (TTP), Shiga toxin-induced and atypical (non-Shiga toxin-induced) hemolytic uremic syndrome (HUS), and the TMAs associated with pregnancy, drugs, and organ transplantation ...
openaire +2 more sources
To review the clinical features and pathophysiologic mechanisms of the thrombotic microangiopathies (TMAs) including acquired and congenital thrombotic thrombocytopenic purpura (TTP), Shiga toxin-induced and atypical (non-Shiga toxin-induced) hemolytic uremic syndrome (HUS), and the TMAs associated with pregnancy, drugs, and organ transplantation ...
openaire +2 more sources
Thrombotic microangiopathy in pregnancy
Thrombosis Research, 2009Following the initial reports by Moschowitz in 1925 [1] and by Baehr et al. in 1936 [2], Singer [3] and Gasser [4] suggested the terms of “thrombotic thrombocytopenic purpura, TTP” and of “hemolytic uremic syndrome, HUS” to describe related disorders consisting of Coombs’ negative hemolytic anemia, thrombocytopenia, and renal failure.
Armando, D'Angelo +2 more
openaire +2 more sources
2019
Abstract The thrombotic microangioapathy (TMA) syndromes are characterized by concomitant occurrence of severe thrombocytopenia, microangiopathic hemolytic anemia, and ischemic end organ dysfunction often of the kidneys. While several of their features overlap in terms of clinical presentation, the pathophysiology and underlying causes ...
Harpreet Singh +2 more
+4 more sources
Abstract The thrombotic microangioapathy (TMA) syndromes are characterized by concomitant occurrence of severe thrombocytopenia, microangiopathic hemolytic anemia, and ischemic end organ dysfunction often of the kidneys. While several of their features overlap in terms of clinical presentation, the pathophysiology and underlying causes ...
Harpreet Singh +2 more
+4 more sources
Syndromes of Thrombotic Microangiopathy
Medical Clinics of North America, 2017Thrombotic thrombocytopenia purpura (TTP) and the hemolytic uremic syndrome (HUS) are rare thrombotic microangiopathies that can be rapidly fatal. Although the acquired versions of TTP and HUS are generally highest on this broad differential, multiple rarer entities can produce a clinical picture similar to TTP/HUS, including microangiopathic hemolysis,
Joseph J, Shatzel, Jason A, Taylor
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