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The thrombotic microangiopathies [PDF]
Pediatric Nephrology, 2008 The term thrombotic microangiopathy (TMA) encompasses a group of conditions that are defined by, or result from, a similar histopathological lesion. Hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP), and several other conditions are associated with TMA.
Bernard S. Kaplan, Lawrence Copelovitch
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Diagnosis and treatment of thrombotic microangiopathy
International Journal of Laboratory Hematology, 2022 Thrombotic microangiopathy (TMA) is characterized by thrombocytopenia, microangiopathic haemolytic anaemia and end organ damage. TMAs have varying underlying pathophysiology and can therefore present with an array of clinical presentations.
Gemma L Thompson, D. Kavanagh
semanticscholar +1 more source
Snakebite Associated Thrombotic Microangiopathy and Recommendations for Clinical Practice
Toxins, 2022 Snakebite is a significant and under-resourced global public health issue. Snake venoms cause a variety of potentially fatal clinical toxin syndromes, including venom-induced consumption coagulopathy (VICC) which is associated with major haemorrhage.
Tina Noutsos +3 more
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Syndromes of Thrombotic Microangiopathy [PDF]
New England Journal of Medicine, 2014 This review article covers the diverse pathophysiological pathways that can lead to microangiopathic hemolytic anemia and a procoagulant state with or without damage to the kidneys and other organs.
Marcus T. Roofthooft +2 more
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Fatal thrombotic microangiopathy case following adeno-associated viral SMN gene therapy
Blood Advances, 2022 Key Points This is the first fatal TMA following SMN AAV9 gene therapy in a child carrying a potential predisposing risk factor in the complement factor I gene.
Julia Guillou +11 more
semanticscholar +1 more source
A new pathological perspective on thrombotic microangiopathy
Kidney Research and Clinical Practice, 2022 Thrombotic microangiopathy (TMA) refers to a condition caused by microvascular injury that includes thrombosis, hemolytic anemia, and thrombocytopenia.
Yong-Jin Kim
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Bone Marrow Transplantation, 2021 Transplant-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication of hematopoietic stem cell transplant (HSCT) with high morbidity and mortality.
J. Young +2 more
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Carfilzomib-Induced Thrombotic Microangiopathy: Focus on Pathogenesis
Journal of Medical Cases, 2022 Drug-induced thrombotic microangiopathies present in similar fashion but have varied pathogenic mechanisms. Carfilzomib is an irreversible proteasome inhibitor.
Odianosen Eigbire-molen +2 more
semanticscholar +1 more source
THROMBOTIC MICROANGIOPATHY IN THE PATHOGENESIS OF OBSTETRIC COMPLICATIONS
Акушерство, гинекология и репродукция, 2016 Thrombotic microangiopathy is one of the most serious thrombotic complications characterized by microvascular thrombosis in various organs and accompanied by thrombocytopenia and hemolytic anemia.
S. V. Akinshina +3 more
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Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
, 2010 Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie +4 more
core +1 more source