Results 11 to 20 of about 131,342 (265)
Clinical Evaluation and Management of Thrombotic Microangiopathy
Arthritis & Rheumatology, 2023 Thrombotic microangiopathy (TMA) refers to a diverse group of diseases that share clinical and histopathologic features. TMA is clinically characterized by microangiopathic hemolytic anemia, consumptive thrombocytopenia, and organ injury that stems from ...
Joshua Leisring, S. Brodsky, S. Parikh
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Chemotherapy-Associated Thrombotic Microangiopathy
Kidney360, 2023 Thrombotic microangiopathy (TMA) is a syndrome of microangiopathic hemolytic anemia and thrombocytopenia with end-organ dysfunction. Although the advent of plasma exchange, immunosuppression, and complement inhibition has improved morbidity and mortality
Abinet M. Aklilu, A. Shirali
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Renal Thrombotic Microangiopathy: A Review.
American Journal of Kidney Diseases, 2022 Thrombotic microangiopathy (TMA) is a pathological lesion observed in a wide spectrum of diseases, triggered by endothelial injury and/or dysfunction. Although TMA lesions are often accompanied by clinical features of microangiopathic hemolytic anemia ...
D. Genest +4 more
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Thrombotic Microangiopathies [PDF]
ISRN Hematology, 2012 Thrombotic microangiopathy results from thrombotic occlusion of the microvasculature leading to fragmentation of red blood cells, profound thrombocytopenia, and a microangiopathic hemolytic anemia with elevation of lactate dehydrogenase and negative direct Coomb’s test.
Radhi, Mohamed, Carpenter, Shannon L.
openaire +3 more sources
Diagnosis and treatment of thrombotic microangiopathy
International Journal of Laboratory Hematology, 2022 Thrombotic microangiopathy (TMA) is characterized by thrombocytopenia, microangiopathic haemolytic anaemia and end organ damage. TMAs have varying underlying pathophysiology and can therefore present with an array of clinical presentations.
Gemma L Thompson, D. Kavanagh
semanticscholar +1 more source
Bone Marrow Transplantation, 2021 Transplant-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication of hematopoietic stem cell transplant (HSCT) with high morbidity and mortality.
J. Young +2 more
semanticscholar +1 more source
Snakebite Associated Thrombotic Microangiopathy and Recommendations for Clinical Practice
Toxins, 2022 Snakebite is a significant and under-resourced global public health issue. Snake venoms cause a variety of potentially fatal clinical toxin syndromes, including venom-induced consumption coagulopathy (VICC) which is associated with major haemorrhage.
T. Noutsos +3 more
semanticscholar +1 more source
Thrombotic microangiopathy following saw-scaled viper () envenoming in Sri Lanka
SAGE Open Medical Case Reports, 2021 The saw-scaled viper ( Echis carinatus ) is considered as a highly venomous snake in Sri Lanka. The clinical manifestations are localized pain and swelling, coagulopathy and renal impairment.
Selladurai Pirasath +2 more
doaj +1 more source
Fatal thrombotic microangiopathy case following adeno-associated viral SMN gene therapy
Blood Advances, 2022 Key Points This is the first fatal TMA following SMN AAV9 gene therapy in a child carrying a potential predisposing risk factor in the complement factor I gene.
Julia Guillou +11 more
semanticscholar +1 more source
Surgical Case Reports, 2022 Background Thrombotic microangiopathy is a syndrome characterized by microangiopathic hemolytic anemia and platelet aggregation, which is caused by endothelial injury, microcirculation thrombosis, and fibrin deposition.
Naohiro Ijiri +4 more
doaj +1 more source