Characteristics and management of thrombotic microangiopathy in kidney transplantation
Thrombotic microangiopathy is not a rare complication of kidney transplantation and is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury with extensive thrombosis of the arterioles and capillaries.
Wonyong Cho +3 more
doaj +1 more source
Making the Correct Diagnosis in Thrombotic Microangiopathy: A Narrative Review
Purpose of review: Thrombotic microangiopathy (TMA) is suspected in patients presenting with thrombocytopenia and evidence of a microangiopathic hemolytic anemia.
P. McFarlane +10 more
semanticscholar +1 more source
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice [PDF]
Atypical hemolytic uremic syndrome (aHUS) is frequently associated in humans with loss-of-function mutations in complement-regulating proteins or gain-of-function mutations in complement-activating proteins.
Atkinson, John P +11 more
core +3 more sources
Pulmonary tumor thrombotic microangiopathy is a fatal disease secondary to some malignant tumors, such as gastric cancer, esophageal cancer, and pancreatic cancer.
Akihiro Kato +6 more
doaj +1 more source
Pathologic manifestations of levamisole-adulterated cocaine exposure. [PDF]
UnlabelledRheumatic manifestations of cocaine have been well described, but more recently, a dramatic increase in the levamisole-adulterated cocaine supply in the United States has disclosed unique pathologic consequences that are distinct from pure ...
Jen, Kuang-Yu, Nolan, Amber L
core +1 more source
Continued monitoring of acute kidney injury survivors might not be necessary in those regaining an estimated glomerular filtration rate > 60 mL/min at 1 year [PDF]
Background. Severe acute kidney injury (AKI) among hospitalized patients often necessitates initiation of short-term dialysis. Little is known about the long-term outcome of those who recover to normal renal function.
Geddes, Colin C. +4 more
core +1 more source
Malignant hypertension-associated thrombotic microangiopathy following cocaine use
Cocaine is one of the most commonly used illicit drugs with distribution and consumption throughout the world. Acute renal failure associated with rhabdomyolysis, direct vasoconstriction and hemodynamic alteration is well described in patients with ...
Rais Lamia +9 more
doaj +1 more source
Transplant-associated thrombotic microangiopathy
Transplant-associated thrombotic microangiopathy (TA-TMA), which is a severe and quite frequent complication of hematopoietic stem cell transplantation (HSCT) in children, significantly influences patients’ overall survival.
Tomasz Jarmoliński
doaj +1 more source
Pregnancy and postpartum are high-risk periods for different forms of thrombotic microangiopathy (TMA). However, the management of pregnancy-associated TMA remains ill-defined.
F. Fakhouri +21 more
semanticscholar +1 more source
Eculizumab for Gemcitabine-Induced Hemolytic Uremic Syndrome: A Novel Therapy for an Emerging Condition [PDF]
Introduction Atypical hemolytic uremic syndrome (aHUS), a thrombotic microangiopathy (TMA), is a disease characterized by hemolytic anemia, thrombocytopenia, and renal impairment. Gemcitabine, a commonly used chemotherapy, is emerging as a cause of aHUS.
Karkowsky, MD, Raphael +1 more
core +2 more sources

