Results 111 to 120 of about 51,562 (315)

A Semi-Automated Approach for Information Extraction, Classification and Analysis of Unstructured Data [PDF]

open access: yesarXiv, 2019
In this paper, we show how Quantitative Narrative Analysis and simple Natural Language Processing techniques apply to the extraction and categorization of data in a sample case study of the Diary of the former President of the Italian Republic (PoR), Giorgio Napolitano. The Diary contains a record of all his institutional meetings. This information, if
arxiv  

Stable discovery of interpretable subgroups via calibration in causal studies [PDF]

open access: yesarXiv, 2020
Building on Yu and Kumbier's PCS framework and for randomized experiments, we introduce a novel methodology for Stable Discovery of Interpretable Subgroups via Calibration (StaDISC), with large heterogeneous treatment effects. StaDISC was developed during our re-analysis of the 1999-2000 VIGOR study, an 8076 patient randomized controlled trial (RCT ...
arxiv  

What Are Appropriate Initial and Salvage Therapies for Patients with Thrombotic Thrombocyopenic Purpura (TTP)?

open access: yesActa Medica, 2004
Although much has been learned about the pathophysiologic process of thrombotic thrombocytopenic purpura (TTP), both diagnostically and therapeutically, since its initial description by Moschowitz in 1924, its etiology and treatments remain, in many ...
Leo McCarthy   +5 more
doaj   +1 more source

Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers

open access: yesCase Reports in Pediatrics, 2020
Acral ischemia/necrosis is one of the rarest but most dreadful complications of thrombotic microangiopathy in pediatric patients. It is more reported with thrombotic thrombocytopenic purpura than with hemolytic and uremic syndrome.
H. Nassih, Z. Lazrak, S. Younous
doaj   +1 more source

Thrombotic Thrombocytopenic Purpura [PDF]

open access: yesBMJ, 1954
In 1924 Moschcowitz reported the case of a patient who died following a brief illness characterized by fever, haernolytic anaemia, a bleeding tendency, and terminal neurological signs. Histological examination revealed widespread hyaline thromboses in the capillaries and terminal arterioles, Baehr et al.
O. C. Lloyd, D. J. Ellison
openaire   +2 more sources

Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
This study investigates the risk of thrombotic microangiopathy (TMA) induced by vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) inhibitors in cancer therapy. Using data from the FDA Adverse Event Reporting System (FAERS), the WHO Global Database for Adverse Drug Reactions (Vigibase), and The Cancer ...
Aimin Jiang   +7 more
wiley   +1 more source

Complete Recovery of Ischemic Cardiomyopathy from Thrombotic Thrombocytopenic purpura

open access: yesClinical Medicine Insights: Cardiology, 2011
A 50 year old male HIV patient on antiretroviral therapy was admitted for chest pain. Upon admission, the patient was found to have elevated cardiac enzymes, acute thrombocytopenia, hemolytic anemia, acute pancreatitis and acute renal failure.
Sainath Gaddam   +7 more
doaj   +1 more source

Thrombotic thrombocytopenic purpura: Toward targeted therapy and precision medicine

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2018
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by severe congenital or immune‐mediated deficiency in ADAMTS13, the enzyme that cleaves von Willebrand factor multimers.
P. Coppo, A. Cuker, J. George
semanticscholar   +1 more source

Blood and Marrow Transplant Clinical Trials Network Toxicity Committee Consensus Summary: Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation [PDF]

open access: yes, 2005
The syndrome of microangiopathic hemolysis associated with renal failure, neurologic impairment, or both is a recognized complication of hematopoietic stem cell transplantation.
Adams, Roberta   +8 more
core   +1 more source

Synergistic effect of shear and ADP on platelet growth on ZTA and Ti6Al4V surfaces [PDF]

open access: yesarXiv, 2020
Continuous-flow ventricular assist devices (VADs) have been an increasingly common, life-saving therapy for advanced heart-failure patients, but elevate the risk of thrombosis due to a combination of non-physiological hemodynamics and synthetic biomaterials.
arxiv  

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