Results 141 to 150 of about 52,108 (298)

Evaluation of the Plasmic Score for the Prediction of Adamts13 Activity in Patients with Thrombotic Microangiopathies

open access: yesProceedings, 2018
The PLASMIC score for the prediction of a likelihood of a severe ADAMTS13 deficiency represents a valid pre-test diagnostic tool to identify patients with thrombotic thrombocytopenic purpura.
Giovanni Tiscia   +17 more
doaj   +1 more source

Pathophysiology of thrombotic thrombocytopenic purpura.

open access: yesBlood, 2017
The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic purpura (TTP).
J. E. Sadler
semanticscholar   +1 more source

Pseudo-thrombotic thrombocytopenic purpura presenting as multi-organ dysfunction syndrome: A rare complication of pernicious anemia

open access: yesSAGE Open Medical Case Reports, 2017
Objective: We present a rare case of pernicious anemia presented as multi-organ dysfunction syndrome, later found to have pseudo-thrombotic thrombocytopenic purpura.
Saroj Kandel   +9 more
doaj   +1 more source

Beyond plasma exchange: novel therapies for thrombotic thrombocytopenic purpura.

open access: yesHematology. American Society of Hematology. Education Program, 2018
The advent of plasma exchange has dramatically changed the prognosis of acute thrombotic thrombocytopenic purpura (TTP). Recent insights into TTP pathogenesis have led to the development of novel therapies targeting pathogenic anti-ADAMTS13 antibody ...
Kathryn E. Dane, Shruti Chaturvedi
semanticscholar   +1 more source

The effect of single nucleotide polymorphisms and mutations on congenital thrombotic thrombocytopenic purpura phenotype [PDF]

open access: yes, 2017
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disease with a reported incidence of 6 cases per million per year in the UK. It is characterised by episodes of microangiopathic haemolytic anaemia and thrombocytopenia, with the ...
Tate, H., Tate, H.
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