Results 41 to 50 of about 28,211 (255)

Long-term Kidney Outcomes in Patients With Acquired Thrombotic Thrombocytopenic Purpura

open access: yesKidney International Reports, 2017
Severe acute kidney injury (AKI) and chronic kidney disease (CKD) are considered to be uncommon in patients with acquired thrombotic thrombocytopenic purpura.
Dustin J. Little   +5 more
doaj   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

open access: yes, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor   +10 more
core   +1 more source

Graves disease-induced thrombotic thrombocytopenic purpura: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Thrombotic thrombocytopenic purpura is an autoimmune disease that carries a high mortality. Very few case reports in the literature have described a relationship between Graves disease and thrombotic thrombocytopenic purpura. We present a case
Saira Chaughtai   +6 more
doaj   +1 more source

Thrombotic microangiopathy and associated renal disorders [PDF]

open access: yes, 2012
Thrombotic microangiopathy (TMA) is a pathological process involving thrombocytopenia, microangiopathic haemolytic anaemia and microvascular occlusion.
Barbour, T   +3 more
core   +1 more source

Vitamin B12 deficiency-induced pseudothrombotic microangiopathy without macrocytosis presenting with acute renal failure: a case report

open access: yesJournal of Medical Case Reports, 2018
Background Vitamin B12 deficiency-induced thrombotic microangiopathy, known as pseudothrombotic microangiopathy, is a rare condition which resembles the clinical features of thrombotic thrombocytopenic purpura but requires a markedly different treatment.
Jennifer Vanoli   +4 more
doaj   +1 more source

The diagnosis and management of the haematologic manifestations of lupus [PDF]

open access: yes, 2016
Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe.
Castro, SG   +2 more
core   +1 more source

Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain

open access: yesHaematologica, 2011
Background The majority of patients diagnosed with thrombotic thrombocytopenic purpura have autoantibodies directed towards the spacer domain of ADAMTS13.Design and Methods In this study we explored the epitope specificity and immunoglobulin class and ...
Wouter Pos   +6 more
doaj   +1 more source

Pediatric thrombotic thrombocytopenic purpura [PDF]

open access: yesEuropean Journal of Haematology, 2018
AbstractChild‐onset thrombotic thrombocytopenic purpura (TTP) is a rare entity of thrombotic microangiopathy (TMA). The pathophysiology of the disease is based on a severe functional deficiency of ADAMTS13 (activity <10%), the specific von Willebrand factor (VWF)‐cleavage protease.
Bérangère S. Joly   +2 more
openaire   +2 more sources

Thrombotic thrombocytopenic purpura [PDF]

open access: yesmemo - Magazine of European Medical Oncology, 2018
Thrombotic thrombocytopenic purpura (TTP) is a clearly defined entity of the thrombotic microangiopathies (TMA), a heterogeneous group of disorders characterized by microangiopathic hemolytic anemia with red cell fragmentation, thrombocytopenia and organ dysfunction due to disturbed microcirculation.
openaire   +2 more sources

Risk factors for silent cerebral infarction in immune‐mediated thrombotic thrombocytopenic survivors

open access: yesBritish Journal of Haematology, EarlyView.
Summary Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) survivors are predisposed to silent cerebral infarctions (SCI) defined as radiological evidence of brain ischaemia without focal symptoms. This study examined risk factors associated with SCI burden in iTTP survivors during remission.
Binish Javed   +13 more
wiley   +1 more source

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