Results 81 to 90 of about 28,211 (255)

Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack   +13 more
wiley   +1 more source

Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2014
Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized.
Milinda Withana   +3 more
doaj   +1 more source

A Rare Case of Thrombotic Thrombocytopenic Purpura Caused by Acute Pancreatitis [PDF]

open access: diamond, 2021
Emin Gemcioğlu   +4 more
openalex   +1 more source

Immune‐Mediated Thrombocytopenia in an Ulcerative Colitis Patient After Initiating Filgotinib Treatment: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff   +2 more
wiley   +1 more source

Eculizumab for Gemcitabine-Induced Hemolytic Uremic Syndrome: A Novel Therapy for an Emerging Condition [PDF]

open access: yes, 2015
Introduction Atypical hemolytic uremic syndrome (aHUS), a thrombotic microangiopathy (TMA), is a disease characterized by hemolytic anemia, thrombocytopenia, and renal impairment. Gemcitabine, a commonly used chemotherapy, is emerging as a cause of aHUS.
Karkowsky, MD, Raphael   +1 more
core   +2 more sources

Acute Hepatitis E Induced the First Episode of Immune-Mediated Thrombotic Thrombocytopenic Purpura: The First Case Report

open access: yesInfection and Drug Resistance, 2023
Fei Lv,1,2 Yue Zhao,2 Xing-Di Yang,2 Han-Zhu Chen,2 Wen-Ya Ren,2 Ling-Xia Chen,2 Qiao-Qiao Yi,2 Wei Zheng,2 Hong-Ying Pan2 1The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China ...
Lv F   +8 more
doaj  

A Diagnostic Challenge: Post‐Transfusion Purpura Unmasked After Multiple Transfusions

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Post‐transfusion purpura (PTP) is a rare immune‐mediated post‐transfusion reaction resulting in severe thrombocytopenia. This case presents a 52‐year‐old female with profound thrombocytopenia following multiple transfusions. PTP was not initially suspected due to her history of comorbid anti‐phospholipid antibody syndrome (APS), chemotherapy ...
Jacintha Thomas   +2 more
wiley   +1 more source

Thrombotic thrombocytopenic purpura: Description and analysis of 23 cases treated in Chile between 2017 and 2022

open access: yesMedwave
Introduction Since the first description of Thrombotic Thrombocytopenic Purpura, caused by a severe deficiency of ADAMTS13, plasma exchange and immunosuppression have become standard treatments, allowing to decrease its high mortality rate.
Daniel Cathalifaud   +6 more
doaj   +1 more source

What Are Appropriate Initial and Salvage Therapies for Patients with Thrombotic Thrombocyopenic Purpura (TTP)?

open access: yesActa Medica, 2004
Although much has been learned about the pathophysiologic process of thrombotic thrombocytopenic purpura (TTP), both diagnostically and therapeutically, since its initial description by Moschowitz in 1924, its etiology and treatments remain, in many ...
Leo McCarthy   +5 more
doaj   +1 more source

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