Results 81 to 90 of about 52,108 (298)
Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture
International Journal of Hematology-Oncology and Stem Cell Research, 2017 Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis.
Prabath K. Abeysundara +5 more
doaj
Transfusion Medicine, EarlyView.Abstract Background Despite efforts to standardise practice using evidence‐based guidelines, fresh frozen plasma (FFP) remains the blood component most frequently prescribed inappropriately. This study assessed the appropriateness of FFP transfusion in two tertiary teaching hospitals and analysed the characteristics of appropriate and inappropriate ...
Jongmin Kim +3 more
wiley +1 more source
Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]
, 2009 Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor +10 more
core +1 more source
Thrombotic thrombocytopenic purpura: Toward targeted therapy and precision medicine
Research and Practice in Thrombosis and Haemostasis, 2018 Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by severe congenital or immune‐mediated deficiency in ADAMTS13, the enzyme that cleaves von Willebrand factor multimers.
P. Coppo, A. Cuker, J. George
semanticscholar +1 more source
Modern concepts of the platelet in health and disease [PDF]
, 1962 Thesis (M.D.)--Boston ...
Estes, J. Worth
core
Comprehensive Physiology, Volume 15, Issue 4, August 2025.Endothelial glycocalyx may be the missing link between angiogenic factors, inflammatory regulation, and endothelial maternal dysfunction in early‐onset preeclampsia and HELLP syndrome. ABSTRACT The pathophysiology of preeclampsia and HELLP syndrome relies on systemic vascular endothelial dysfunction, resulting from angiogenic imbalance due to abnormal ...
Anthony Atallah +4 more
wiley +1 more source
A rare case of hereditary thrombotic thrombocytopenic purpura in a toddler
Liječnički vjesnik, 2023 Hereditary thrombotic thrombocytopenic purpura (hTTP) is a thrombotic microangiopathy caused by pathogenic variants in the ADAMTS13 gene resulting in highly reduced activity of von Willebrand factor-cleaving metalloprotease.
Ozana Jakšić +2 more
doaj +1 more source
Cerebral fat embolism syndrome mimicking thrombotic thrombocytopenic purpura in a patient with Hemoglobin SC disease [PDF]
, 2016 Case Presentation A 54 year‐old man with hemoglobin SC disease (HbSC) and a history of substance abuse presented to the Emergency Department from a nursing home with two days of progressive weakness, shortness of breath, and lower back pain.
Devnani, Rohit +2 more
core +1 more source
Autoimmune thrombotic thrombocytopenic purpura (TTP) associated with COVID-19
Annals of Hematology, 2020 Dear Editor: A 57-year-old woman with a history of hypertension and breast cancer in complete remission was seen in lateMarch 2020 at the emergency ward in a private clinic with dry cough, anosmia, and dysgeusia.
N. Albiol, R. Awol, R. Martino
semanticscholar +1 more source
HemaSphere, Volume 9, Issue 7, July 2025.Abstract By proteolyzing prothrombotic von Willebrand factor (VWF) multimers, ADAMTS13 (A Disintegrin And Metalloproteinase with ThromboSpondin type‐1 repeats, member 13) ensures balanced hemostasis and prevents microvascular thrombosis. ADAMTS13's conformational regulation is not only crucial for its enzymatic function, but also for the ...
Quintijn Bonnez, Karen Vanhoorelbeke
wiley +1 more source