Results 51 to 60 of about 1,923 (242)
The paper introduces the description of a new regulated throttle orifice design, the laboratory bench to study its characteristics and the results of experimental determination of the orifice hydraulic resistance coefficients. The authors have made the valid conclusion on the prospects of applying the device to adjust liquid or gas flow in different ...
S. V. Dolgov +3 more
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
This paper presents the results from 1.6 litre, 4 cylinders stratified charge compressed natural gas (CNG) direct injection engine with boosting device. A turbocharger with compressor trim of 40 was used to increase engine output.
Amiruddin Hilmi +4 more
doaj +1 more source
A range extender (RE) is a device used in electric vehicles (EVs) to generate electricity on-board, enabling them to significantly reduce the number of required batteries and/or extend the vehicle driving range to allow occasional long trips.
F. P. Brito +5 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
An Automatic-Throttle Device for Airspeed Control During Flare to Field Landings. [PDF]
This study is a continuation of the investigations in the use of automatic-throttle compensation systems. The previous investigations demonstrated the capability of such systems in alleviating the problems of aircraft speed instability in the carrier ...
Elich, Robert Louis
core
A Transient Driver for Fast Opening of Diaphragmless Shock Tube
Diaphragmless shock tubes, which circumvent diaphragm rupture, effectively mitigate interference from diaphragm fragments in the test section, thereby significantly enhancing testing frequency and result reproducibility.
Shijie BAI +4 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source

