Results 61 to 70 of about 1,923 (242)

Study on pressure‐controlled sliding sleeve of jet breaking for natural gas hydrate mining based on throttle pressure drop principle

Energy Science & Engineering, 2020
In order to reduce operating cost of deep‐sea natural gas hydrate (NGH) solid‐state fluidization mining (SSFM), a device for controlling opening and closing of jet nozzles is required.
Yang Tang, Jiaxin Yao, Yin He, Peng Sun, Xin Jin   +4 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Synthesis of lever-blade dampers with enhanced mechanical structure

Trudy Odesskogo Politehničeskogo Universiteta, 2015
Since the torsion bar represents just an elastic element, the energy dissipation in suspensions problem is highly relevant for its application. Currently in quality of a dissipation device in torsion suspension are used the hydraulic dampers with movable
Igor I. Sydorenko, Yi Heng Zhang
doaj   +1 more source

Ergonomic Evaluation of Vibrations of a Rototiller with New Blade [PDF]

Journal of Agricultural Machinery, 2017
Introduction One of the most important problems arising with operation of the conventional rototillers is severe vibration of the machine handle which is transmitted to the user’s hands, arms and shoulders.
H Gholami, D Kalantari, M Rajabi Vandechali   +2 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Throttle device

, 2009
Дросельний пристрій містить корпус, еластичну розтягуючу вставку, регулюючо-запірні елементи та рукоятки регулювання. Регулюючо-запірний елемент виконаний у вигляді двох барабанів.Дроссельное устройство содержит корпус, эластичную растягивающую вставку ...
Степанковський, Роман Володимирович, Ратушняк, Георгий Сергеевич, Ratushniak, Heorhii Serhiiovych, Ратушняк, Георгій Сергійович, Stepankovskyi, Roman Volodymyrovych, Степанковский, Роман Владимирович   +5 more
core  

Future Throttle Valve

The Michigan Aeronautical Science Association (MASA) has commissioned a group to design, build, and test a throttle valve that will be used in conjunction with other new technologies to give future rockets the ability to throttle their thrust, resulting ...
Van Noord, Abigail, Assenov, Ioan, Hintzen, Michael, Beveridge, Noah   +3 more
core   +1 more source

Smart Shift Decision Method Based on Stacked Autoencoders

Journal of Control Science and Engineering, 2018
Manual calibration and testing on real vehicles are common methods of generating shifting schedules for newly developed vehicles. However, these methods are time-consuming.
Zengcai Wang, Yazhou Qi, Guoxin Zhang, Lei Zhao   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source