Results 31 to 40 of about 12,470 (162)

Surgical management prospects for myasthenia gravis in Nigeria: A preliminary report of Enugu experience

International Journal of Medicine and Health Development, 2022
Background: Myasthenia gravis (MG) is an acquired autoimmune neuromuscular disease characterized by fatigable and variable weakness of skeletal muscles as a result of autoimmune attack on postsynaptic antigenic targets.
Ijeoma B Ndionuka, Ikenna O Onwuekwe, Stella O Ekenze, Birinus Ezeala-Adikaibe   +3 more
doaj   +1 more source

SUBPOPULATION PROFILES OF T HELPER CELLS EXPRESSING CD45RA AND CD31 MARKERS IN CHILDREN AFTER THYMECTOMY PERFORMED UPON SURGICAL TREATMENT OF CONGENITAL HEART DISEASE

Медицинская иммунология, 2016
Thymectomy is a stage of surgery when treating some congenital heart defects. Thymus gland is the central organ of immune system. This organ is the primary site of T-cell lymphopoiesis and central tolerance to autoantigens during fetal and early ...
Yu. I. Rovda, S. A. Shmulevich, A. V. Shabaldin, E. B. Lukoyanycheva   +3 more
doaj   +1 more source

Early Thymectomy Is Associated With Long-Term Impairment of the Immune System: A Systematic Review

Frontiers in Immunology, 2021
Background and AimsCongenital heart diseases (CHDs) are diagnosed in approximately 9 in 1,000 newborns, and early cardiac corrective surgery often requires partial or complete thymectomy.
Nara Vasconcelos Cavalcanti, Patrícia Palmeira, Marcelo Biscegli Jatene, Mayra de Barros Dorna, Magda Carneiro-Sampaio, Magda Carneiro-Sampaio   +5 more
doaj   +1 more source

Factors predicting perioperative outcomes in patients with myasthenia gravis or thymic neoplasms undergoing thymectomy by video-assisted thoracoscopic approach

Journal of Minimal Access Surgery, 2022
Background: The purpose of this study was to identify the factors which predict the perioperative outcomes after video-assisted thoracoscopic surgery (VATS) thymectomy in patients with myasthenia gravis (MG) or thymic neoplasms Patients and Methods: Data
B Vigneshwaran, Sanjeev Kumar Bhoi, Mukund Namdev Sable, Dillip Muduly, Mahesh Sultania, Menkha Jha, Sudipta Mohakud, Madhabananda Kar   +7 more
doaj   +1 more source

Complete Remission of Generalized Myasthenia Gravis by Corticosteroid Treatment Alone without Thymectomy

Case Reports in Neurology, 2011
Many long-term, follow-up studies have shown that steroids are effective in patients with myasthenia gravis (MG) who have undergone thymectomy. However, few long-term studies have documented the response of MG to steroids alone.
Hiroshi Kataoka, Yoshiko Furiya, Satoshi Ueno   +2 more
doaj   +1 more source

Medically resistant juvenile myasthenia gravis following thymectomy: Role for FDG PET/CT

Journal of Pediatric Surgery Case Reports, 2020
Thymectomy is part of a multimodal treatment strategy for juvenile myasthenia gravis. Symptoms that persist following thymectomy may be due to residual or ectopic thymic tissue.
Florence Ngu, Michael Cardamone, Dylan Wanaguru, Bruce Currie, Eva Alina Wegner, Ian Andrews, Walter Haindl   +6 more
doaj  

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

Thymectomy in Non-Thymomatous Myasthenia Gravis: Does An RCT Solve The 75-Year-Old Controversy?

Annals of Indian Academy of Neurology, 2020
The role of thymectomy in thymomatous myasthenia gravis (MG) is unambiguous. However, its role in non-thymomatous MG (NTMG) remains debatable. The evidence till date is not robust.
Nishita Singh, Vinay Goyal
doaj   +1 more source

Robot‐Assisted Versus Open Surgery for the Resection of Large Thymomas: A Retrospective Cohort Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Robot‐assisted thoracic surgery (RATS) is increasingly becoming the preferred surgical method for the resection of thymomas. We initiated the current study to evaluate perioperative outcomes and early recurrence associated with the surgical approach.
Benedikt Niedermaier, Raffaella Griffo, Florian Eichhorn, Laura V. Klotz, Heidrun Grosch, Thomas Muley, Hauke Winter, Martin E. Eichhorn   +7 more
wiley   +1 more source

Predictive Value of Perioperative Blood Lactic Acid Levels for Postoperative Crisis in Myasthenia Gravis Patients Undergoing Thymectomy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Postoperative myasthenic crisis (POMC), which occurs specifically after thymectomy in myasthenia gravis (MG) patients, is a serious complication with known risk factors such as prior myasthenic crisis. However, the predictive value of perioperative blood lactic acid levels (BLAL) for POMC remains unclear.
Jianyong Zou, Xiaojing Yao, Zhihao Liu, Zhenguo Liu, Haoshuai Zhu, Xin Zhang, Zhenguang Chen, Chunhua Su   +7 more
wiley   +1 more source