Results 41 to 50 of about 9,363 (178)
Cytokine Profiles in Myasthenia Gravis Subgroups and the Lack of Any Effect of Immunosuppression
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Myasthenia gravis (MG) is a clinically and immunologically heterogeneous autoimmune disease and there is little known about the differential effects of cytokines in disease subgroups. This study aimed to compare serum cytokine profiles across distinct MG subgroups, including early‐onset MG (EOMG), late‐onset MG (LOMG), muscle‐
Merve Cebi +6 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor +5 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Urinary dysfunction has been reported in association with myasthenic syndromes, including myasthenia gravis (MG), Lambert–Eaton myasthenic syndrome (LEMS), and congenital myasthenic syndromes (CMS), but evidence regarding its prevalence, clinical impact, pathophysiology, and management remains limited.
Julia M. Augustin +13 more
wiley +1 more source
Early Thymectomy Is Associated With Long-Term Impairment of the Immune System: A Systematic Review
Frontiers in Immunology, 2021 Background and AimsCongenital heart diseases (CHDs) are diagnosed in approximately 9 in 1,000 newborns, and early cardiac corrective surgery often requires partial or complete thymectomy.
Nara Vasconcelos Cavalcanti +5 more
doaj +1 more source
Neurology and Clinical Neuroscience, EarlyView.ABSTRACT Myasthenia gravis (MG) associated with disseminated thymoma is often refractory to conventional treatments due to continuous autoantibody production. The optimal treatment strategy, particularly the combination of complement component 5 (C5) inhibitor, neonatal Fc receptor (FcRn) antagonist, and surgical resection in thymoma‐associated ...
Hiroyuki Takenaka +3 more
wiley +1 more source
Pure Red Cell Aplasia Associated with Thymolipoma: Complete Anaemia Resolution following Thymectomy
Case Reports in Hematology, 2018 Pure red cell aplasia is an uncommon cause of anaemia rarely associated with thymoma. A combination of immunosuppressive therapy and thymectomy offers a potential cure. Thymectomy alone rarely results in anaemia resolution.
David Ferreira +3 more
doaj +1 more source
Neurological Research and Practice, 2023 Background Myasthenia gravis (MG) is a rare neuromuscular disorder. Symptoms can range from ptosis only to life threatening myasthenic crisis. Thymectomy is recommended for anti-acetylcholine receptor-antibody positive patients with early-onset MG. Here,
Hruy Menghesha +12 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundTo improve the preoperative diagnostic accuracy and reduce the non-therapeutic thymectomy rate, we established a comprehensive predictive nomogram based on radiomics data and computed tomography (CT) features and further explored its potential ...
Zhou Zhou +5 more
doaj +1 more source
“White and Clear” (WaC): A tunable hydrophilic tissue clearing strategy for multi‐species 3D imaging
VIEW, EarlyView.Optical tissue clearing methods help scientists make tissues transparent to image structures deep inside organs in 3D, but many existing techniques are limited in performance and difficulty. In this study, we developed an optimized clearing method called WaC (White and Clear), which improves upon existing techniques by combining efficient tissue ...
Vicente Llorente +12 more
wiley +1 more source
Thymectomy in Juvenile Myasthenia Gravis Is Safe Regarding Long Term Immunological Effects
Frontiers in Neurology, 2021 Thymectomy is an established treatment in adult MG and also recommended for the treatment of post-pubertal onset juvenile MG. Whether the youngest children should be thymectomized is still debated.
Trine H. Popperud +9 more
doaj +1 more source