Results 31 to 40 of about 9,300 (176)

Thymectomy for myasthenia gravis [PDF]

open access: yesPostgraduate Medical Journal, 1998
SummaryThe pathophysiological role of the thymus in myasthenia gravis, and the mechanism of therapeutic effect of thymectomy, are incompletely understood. Nevertheless, thymectomy is a valuable treatment modality in selected patients with generalised myasthenia gravis.
J D, Urschel, R P, Grewal
openaire   +2 more sources

Thymectomy via parasternal approach in patients with miasthenia

open access: yesВестник хирургии имени И.И. Грекова, 2021
A new approach for thymectomy in case of mediastinal shifting is proposed. Parasternal access provides optimal conditions for performing an adequate thymectomy, does not require single lung ventilation and could be used after previously performed ...
O. V. Pikin   +4 more
doaj   +1 more source

Thymectomy for myasthenia gravis [PDF]

open access: yesThorax, 1972
Between 1951 and 1971 thymectomy was performed on 41 patients with myasthenia gravis. They were selected from a total group of 95 myasthenic patients receiving anticholinesterase therapy. The criteria for selecting patients for thymectomy and the assessment of their progress after operation are described.
F R, Edwards, A, Wilson
openaire   +2 more sources

SUBPOPULATION PROFILES OF T HELPER CELLS EXPRESSING CD45RA AND CD31 MARKERS IN CHILDREN AFTER THYMECTOMY PERFORMED UPON SURGICAL TREATMENT OF CONGENITAL HEART DISEASE

open access: yesМедицинская иммунология, 2016
Thymectomy is a stage of surgery when treating some congenital heart defects. Thymus gland is the central organ of immune system. This organ is the primary site of T-cell lymphopoiesis and central tolerance to autoantigens during fetal and early ...
Yu. I. Rovda   +3 more
doaj   +1 more source

Surgical management prospects for myasthenia gravis in Nigeria: A preliminary report of Enugu experience

open access: yesInternational Journal of Medicine and Health Development, 2022
Background: Myasthenia gravis (MG) is an acquired autoimmune neuromuscular disease characterized by fatigable and variable weakness of skeletal muscles as a result of autoimmune attack on postsynaptic antigenic targets.
Ijeoma B Ndionuka   +3 more
doaj   +1 more source

Meta-Analysis of Limited Thymectomy versus Total Thymectomy for Masaoka Stage I and II Thymoma

open access: yesJournal of Chest Surgery, 2021
Background: This meta-analysis aimed to evaluate the incidence of tumor recurrence, postoperative myasthenia gravis, postoperative complications, and overall survival after limited versus total thymectomy for Masaoka stage I and II thymoma. Methods: A
Mohan Venkatesh Pulle   +4 more
doaj   +1 more source

Rare But Risky: Clinical Impacts of Pneumothorax After Thyroidectomy and Parathyroidectomy

open access: yesThe Laryngoscope, EarlyView.
Postoperative pneumothorax (PPTX) is rare after thyroidectomy or parathyroidectomy, occurring in up to 0.10% of cases. However, it is associated with increased risks of all‐cause mortality, adverse respiratory events, and healthcare utilization rates in up to 1 year after surgery, deeming PPTX as a potential marker of increased postoperative ...
Jessan A. Jishu   +7 more
wiley   +1 more source

Non‐Cyclic Rozanolixizumab Administration in Complex Generalized Myasthenia Gravis

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Rozanolixizumab, an inhibitor of the neonatal Fc receptor (FcRn), is used to treat patients with generalized myasthenia gravis (gMG) refractory to standard therapies. However, the approved six‐week cyclic regimen may be associated with a “wearing‐off” effect and disease fluctuations. We evaluated the non‐cyclic administration
Marc Abi Aoun   +6 more
wiley   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

open access: yesImmunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros   +5 more
wiley   +1 more source

Early Thymectomy Is Associated With Long-Term Impairment of the Immune System: A Systematic Review

open access: yesFrontiers in Immunology, 2021
Background and AimsCongenital heart diseases (CHDs) are diagnosed in approximately 9 in 1,000 newborns, and early cardiac corrective surgery often requires partial or complete thymectomy.
Nara Vasconcelos Cavalcanti   +5 more
doaj   +1 more source

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