Results 31 to 40 of about 9,363 (178)

SUBPOPULATION PROFILES OF T HELPER CELLS EXPRESSING CD45RA AND CD31 MARKERS IN CHILDREN AFTER THYMECTOMY PERFORMED UPON SURGICAL TREATMENT OF CONGENITAL HEART DISEASE

open access: yesМедицинская иммунология, 2016
Thymectomy is a stage of surgery when treating some congenital heart defects. Thymus gland is the central organ of immune system. This organ is the primary site of T-cell lymphopoiesis and central tolerance to autoantigens during fetal and early ...
Yu. I. Rovda   +3 more
doaj   +1 more source

Surgical management prospects for myasthenia gravis in Nigeria: A preliminary report of Enugu experience

open access: yesInternational Journal of Medicine and Health Development, 2022
Background: Myasthenia gravis (MG) is an acquired autoimmune neuromuscular disease characterized by fatigable and variable weakness of skeletal muscles as a result of autoimmune attack on postsynaptic antigenic targets.
Ijeoma B Ndionuka   +3 more
doaj   +1 more source

Rare But Risky: Clinical Impacts of Pneumothorax After Thyroidectomy and Parathyroidectomy

open access: yesThe Laryngoscope, EarlyView.
Postoperative pneumothorax (PPTX) is rare after thyroidectomy or parathyroidectomy, occurring in up to 0.10% of cases. However, it is associated with increased risks of all‐cause mortality, adverse respiratory events, and healthcare utilization rates in up to 1 year after surgery, deeming PPTX as a potential marker of increased postoperative ...
Jessan A. Jishu   +7 more
wiley   +1 more source

Thymectomy for myasthenia gravis [PDF]

open access: yesPostgraduate Medical Journal, 1998
SummaryThe pathophysiological role of the thymus in myasthenia gravis, and the mechanism of therapeutic effect of thymectomy, are incompletely understood. Nevertheless, thymectomy is a valuable treatment modality in selected patients with generalised myasthenia gravis.
J D, Urschel, R P, Grewal
openaire   +2 more sources

Fatigue in Myasthenia Gravis: Recent Advances and Emerging Concepts

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Fatigue is a common, often disabling symptom in myasthenia gravis (MG), distinct from muscle fatigability, and strongly associated with reduced quality of life. This narrative review examines current evidence on fatigue in MG, its patient impact, and future research directions. Earlier studies, mostly small and heterogeneous, reported a highly
Yvonne J. M. Campman   +3 more
wiley   +1 more source

Meta-Analysis of Limited Thymectomy versus Total Thymectomy for Masaoka Stage I and II Thymoma

open access: yesJournal of Chest Surgery, 2021
Background: This meta-analysis aimed to evaluate the incidence of tumor recurrence, postoperative myasthenia gravis, postoperative complications, and overall survival after limited versus total thymectomy for Masaoka stage I and II thymoma. Methods: A
Mohan Venkatesh Pulle   +4 more
doaj   +1 more source

Thymectomy for myasthenia gravis [PDF]

open access: yesThorax, 1972
Between 1951 and 1971 thymectomy was performed on 41 patients with myasthenia gravis. They were selected from a total group of 95 myasthenic patients receiving anticholinesterase therapy. The criteria for selecting patients for thymectomy and the assessment of their progress after operation are described.
F R, Edwards, A, Wilson
openaire   +2 more sources

Clinical Characteristics and Treatment Management of Seronegative Myasthenia Gravis: A Systematic Review of the Literature

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Seronegative myasthenia gravis (SNMG) is characterized by the absence of detectable autoantibodies against known MG targets, despite clinical and electrophysiological evidence of a postsynaptic neuromuscular junction disorder. The aim of this systematic review was to better define clinical features, diagnostic clues and treatment outcome of ...
Massimiliano Ugo Verza   +6 more
wiley   +1 more source

Thymectomy and myasthenia gravis [PDF]

open access: yesProceedings of the National Academy of Sciences, 2020
Myasthenia gravis (MG) is a disorder of the neuromuscular junction mediated by the actions of autoantibodies directed against one of several proteins expressed on the postjunction muscle membrane. For the large majority of MG patients the target for the autoantibodies is the acetylcholine receptor (AChR) (1) that interacts with acetylcholine, the ...
Robert P. Lisak, David P. Richman
openaire   +2 more sources

Treatment Preferences of Patients With Myasthenia Gravis: A Qualitative Study

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims The burden of myasthenia gravis (MG) is often underestimated, and studies usually focus on the symptom burden. However, treatment‐related adverse events also contribute to patients' burdens and affect their treatment decisions.
Meg Mendoza   +6 more
wiley   +1 more source

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