Results 31 to 40 of about 9,300 (176)
Thymectomy for myasthenia gravis [PDF]
SummaryThe pathophysiological role of the thymus in myasthenia gravis, and the mechanism of therapeutic effect of thymectomy, are incompletely understood. Nevertheless, thymectomy is a valuable treatment modality in selected patients with generalised myasthenia gravis.
J D, Urschel, R P, Grewal
openaire +2 more sources
Thymectomy via parasternal approach in patients with miasthenia
A new approach for thymectomy in case of mediastinal shifting is proposed. Parasternal access provides optimal conditions for performing an adequate thymectomy, does not require single lung ventilation and could be used after previously performed ...
O. V. Pikin +4 more
doaj +1 more source
Thymectomy for myasthenia gravis [PDF]
Between 1951 and 1971 thymectomy was performed on 41 patients with myasthenia gravis. They were selected from a total group of 95 myasthenic patients receiving anticholinesterase therapy. The criteria for selecting patients for thymectomy and the assessment of their progress after operation are described.
F R, Edwards, A, Wilson
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Thymectomy is a stage of surgery when treating some congenital heart defects. Thymus gland is the central organ of immune system. This organ is the primary site of T-cell lymphopoiesis and central tolerance to autoantigens during fetal and early ...
Yu. I. Rovda +3 more
doaj +1 more source
Background: Myasthenia gravis (MG) is an acquired autoimmune neuromuscular disease characterized by fatigable and variable weakness of skeletal muscles as a result of autoimmune attack on postsynaptic antigenic targets.
Ijeoma B Ndionuka +3 more
doaj +1 more source
Meta-Analysis of Limited Thymectomy versus Total Thymectomy for Masaoka Stage I and II Thymoma
Background: This meta-analysis aimed to evaluate the incidence of tumor recurrence, postoperative myasthenia gravis, postoperative complications, and overall survival after limited versus total thymectomy for Masaoka stage I and II thymoma. Methods: A
Mohan Venkatesh Pulle +4 more
doaj +1 more source
Rare But Risky: Clinical Impacts of Pneumothorax After Thyroidectomy and Parathyroidectomy
Postoperative pneumothorax (PPTX) is rare after thyroidectomy or parathyroidectomy, occurring in up to 0.10% of cases. However, it is associated with increased risks of all‐cause mortality, adverse respiratory events, and healthcare utilization rates in up to 1 year after surgery, deeming PPTX as a potential marker of increased postoperative ...
Jessan A. Jishu +7 more
wiley +1 more source
Non‐Cyclic Rozanolixizumab Administration in Complex Generalized Myasthenia Gravis
ABSTRACT Introduction/Aims Rozanolixizumab, an inhibitor of the neonatal Fc receptor (FcRn), is used to treat patients with generalized myasthenia gravis (gMG) refractory to standard therapies. However, the approved six‐week cyclic regimen may be associated with a “wearing‐off” effect and disease fluctuations. We evaluated the non‐cyclic administration
Marc Abi Aoun +6 more
wiley +1 more source
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros +5 more
wiley +1 more source
Early Thymectomy Is Associated With Long-Term Impairment of the Immune System: A Systematic Review
Background and AimsCongenital heart diseases (CHDs) are diagnosed in approximately 9 in 1,000 newborns, and early cardiac corrective surgery often requires partial or complete thymectomy.
Nara Vasconcelos Cavalcanti +5 more
doaj +1 more source

