Results 41 to 50 of about 22,154 (275)

Early Thymectomy Is Associated With Long-Term Impairment of the Immune System: A Systematic Review

Frontiers in Immunology, 2021
Background and AimsCongenital heart diseases (CHDs) are diagnosed in approximately 9 in 1,000 newborns, and early cardiac corrective surgery often requires partial or complete thymectomy.
Nara Vasconcelos Cavalcanti, Patrícia Palmeira, Marcelo Biscegli Jatene, Mayra de Barros Dorna, Magda Carneiro-Sampaio, Magda Carneiro-Sampaio   +5 more
doaj   +1 more source

An update on treatments in myasthenia gravis [PDF]

, 2017
This month, we discuss three papers which publish the results of trials into potential treatment approaches to myasthenia gravis (MG). When treatment with cholinesterase inhibitors alone fails to control symptoms, treatment with steroids may be required,
Jones, Lliwen, Robertson, Neil
core   +3 more sources

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Avenues of future research in homotransplantation of the liver with particular reference to hepatic supportive procedures, antilymphocyte serum, and tissue typing [PDF]

, 1966
Three general areas of research which bear on the developing field of liver transplantation are reviewed. These are: (1) the prospects of obtaining better immunosuppression with particular reference to heterologous antilymphocyte serum; (2) the possible ...
Anderson, Bibler, Eiseman, Gray, Halgrimson, Hill, Jeejeebhoy, Marchioro, Mikaeloff, Monaco, Monaco, Norman, Patrick, Rich, Robert J. McCardle, Sacks, Starzl, Starzl, Starzl, Starzl, Steinberg, Tanous D. Faris, Thaler, Thomas E. Starzl, Thomas L. Marchioro, Vang, Waksman, Woodruff, Woodruff, Woodruff, Woodruff, Yoji Iwaski   +31 more
core   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Factors predicting perioperative outcomes in patients with myasthenia gravis or thymic neoplasms undergoing thymectomy by video-assisted thoracoscopic approach

Journal of Minimal Access Surgery, 2022
Background: The purpose of this study was to identify the factors which predict the perioperative outcomes after video-assisted thoracoscopic surgery (VATS) thymectomy in patients with myasthenia gravis (MG) or thymic neoplasms Patients and Methods: Data
B Vigneshwaran, Sanjeev Kumar Bhoi, Mukund Namdev Sable, Dillip Muduly, Mahesh Sultania, Menkha Jha, Sudipta Mohakud, Madhabananda Kar   +7 more
doaj   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Development and Validation of a CT-Based Radiomics Nomogram in Patients With Anterior Mediastinal Mass: Individualized Options for Preoperative Patients

Frontiers in Oncology, 2022
BackgroundTo improve the preoperative diagnostic accuracy and reduce the non-therapeutic thymectomy rate, we established a comprehensive predictive nomogram based on radiomics data and computed tomography (CT) features and further explored its potential ...
Zhou Zhou, Yanjuan Qu, Yurong Zhou, Binchen Wang, Weidong Hu, Yiyuan Cao   +5 more
doaj   +1 more source

Hybrid endoscopic thymectomy : combined transesophageal and transthoracic approach in a survival porcine model with cadaver assessment [PDF]

, 2014
BACKGROUND: Video-assisted thoracoscopic surgery thymectomy has been used in the treatment of Myastenia Gravis and thymomas (coexisting or not).
Alice Miranda, Aníbal Ferreira, AP Yim, C Rolanda, C Yang, Carla Rolanda, DM Meyer, DW Gee, E Lima, GD Palma De, H Inoue, J Loscertales, J Moreira-Pinto, J Moreira-Pinto, J Moreira-Pinto, JC Ruckert, Jorge Correia-Pinto, João Moreira-Pinto, K Parikh, K Sumiyama, L Yu, MJ Mack, MJ Mack, MS Allen, RJ Landreneau, RJ Lewia, S Takeo, SR Hazelrigg, T Agasthian, WH Coltharp   +29 more
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source