Results 61 to 70 of about 21,282 (258)

Redefining the Immunobiology of Organ Transplantation for New Clinical Horizons

Scandinavian Journal of Immunology, Volume 102, Issue 2, August 2025.
ABSTRACT Traditional organ transplantation relies on the Self–Non‐self (SNS) model of immunity, focusing on donor–recipient compatibility and aggressive immunosuppression to prevent acute rejection. Although effective early, this strategy does not prevent chronic rejection and cannot account for operational tolerance, failure of perfectly HLA‐matched ...
Masoud H. Manjili
wiley   +1 more source

Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song, Hantian Liang, Fang Nan, Wenjing Chen, Junyao Li, Liu He, Yiping Cun, Zhenhong Li, Wei Zhang, Dunfang Zhang   +9 more
wiley   +1 more source

Thymic hyperplasia as a rare etiology of pure red cell aplasia: A case report [PDF]

Vojnosanitetski Pregled
Introduction. Thymic hyperplasia is a rare condition caused by an increase in cellular thymic mass and, in some cases, is associated with autoimmune diseases, such as pure red cell aplasia (PRCA).
Arsenović Isidora, Leković Danijela, Šefer Dijana, Pavlović Miroslav, Ivanović Jelena, Smiljanić Mihailo, Bogdanović Andrija   +6 more
doaj   +1 more source

Thymoma with Myasthenia Gravis in Adolescent [PDF]

, 2011
Thymomas are exceedingly rare in the first 20 years of life, Thymic lesions comprise approximately 2–3% of all pediatric mediastinal tumors and include thymic cysts, hyperplasia, carcinoma, and thymomas.
Balaiah, K, Nayak, Ganesh, Shetty, Prasad K, Shetty, Prasanna K   +3 more
core   +1 more source

Hybrid endoscopic thymectomy : combined transesophageal and transthoracic approach in a survival porcine model with cadaver assessment [PDF]

, 2014
BACKGROUND: Video-assisted thoracoscopic surgery thymectomy has been used in the treatment of Myastenia Gravis and thymomas (coexisting or not).
Alice Miranda, Aníbal Ferreira, AP Yim, C Rolanda, C Yang, Carla Rolanda, DM Meyer, DW Gee, E Lima, GD Palma De, H Inoue, J Loscertales, J Moreira-Pinto, J Moreira-Pinto, J Moreira-Pinto, JC Ruckert, Jorge Correia-Pinto, João Moreira-Pinto, K Parikh, K Sumiyama, L Yu, MJ Mack, MJ Mack, MS Allen, RJ Landreneau, RJ Lewia, S Takeo, SR Hazelrigg, T Agasthian, WH Coltharp   +29 more
core   +1 more source

Mycobacterium abscessus Pulmonary Disease in a Myasthenia Gravis Patient: A Case Report

Respirology Case Reports, Volume 13, Issue 7, July 2025.
Reports on Mycobacterium abscessus complex (MABC) pulmonary disease and Myasthenia Gravis (MG) are rare; to our knowledge, this is the second case describing successful treatment of MABC pulmonary infection in this population and the first with current guideline‐directed therapy.
Daisy Lu, Steven Y. C. Tong, Belinda Cruse, Kasha P. Singh, Justin T. Denholm, Megan Rees   +5 more
wiley   +1 more source

Pure Red Cell Aplasia Associated with Thymolipoma: Complete Anaemia Resolution following Thymectomy

Case Reports in Hematology, 2018
Pure red cell aplasia is an uncommon cause of anaemia rarely associated with thymoma. A combination of immunosuppressive therapy and thymectomy offers a potential cure. Thymectomy alone rarely results in anaemia resolution.
David Ferreira, Royston Ponraj, Adrian Yeung, Jillian de Malmanche   +3 more
doaj   +1 more source

Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen. [PDF]

, 1987
The transmission of a lymphomagenic agent(s) from the bone marrow of irradiated mice to thymic target cells has been demonstrated by: (a) the induction of T cell lymphomas in nonirradiated thymic grafts implanted in irradiated, Thy-l-congenic mice, (b ...
Hansteen, GA, Lieberman, M, McCune, JM, Scott, ML, Weissman, IL, White, JH   +5 more
core  

It's Time to Unite: Diversity and Coordination of Thymic Stromal Cells for T Cell Selection and Organ Integrity

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT The thymus is a primary lymphoid organ for generating a diverse yet self‐tolerant T cell repertoire. Among the thymic stromal cells that create the thymic microenvironment, thymic epithelial cells (TECs) have received the most attention because of their distinctive functions in the repertoire selection of T cells. Other types of thymic stromal
Ryunosuke Muro, Takeshi Nitta
wiley   +1 more source

Descriptive analysis of therapeutic outcomes between thoracoscopic and transsternal thymectomy in myasthenia gravis patients from 2011 to 2021

Journal of Cardiothoracic Surgery
Background Myasthenia gravis is an autoimmune disease with high prevalence of thymus disorders, in which, thymectomy is considered one of the therapeutic approaches in improving the patients’ clinical outcomes.
Mahdiye Lashkarizadeh, Vahid Haghollahi, Nazanin Zeinali Nezhad, Mohammadreza Lashkarizadeh, Amirhossein Shahpar   +4 more
doaj   +1 more source