Results 31 to 40 of about 624,402 (215)

Molecular predictors of response to pembrolizumab in thymic carcinoma

Cell Reports Medicine, 2021
Summary: Thymic carcinoma is rare and has a poorer prognosis than thymomas. The treatment options are limited after failure of platinum-based chemotherapy.
Yongfeng He, Archana Ramesh, Yuriy Gusev, Krithika Bhuvaneshwar, Giuseppe Giaccone   +4 more
doaj   +1 more source

Thymoma and thymic carcinoma [PDF]

European Journal of Cardio-Thoracic Surgery, 2010
Thymoma and thymic carcinoma are an extremely heterogeneous group of neoplastic lesions with an exceedingly wide spectrum of morphologic appearances. They show different presentations with a variable and unpredictable evolution ranging from an indolent non-invasive attitude to a highly infiltrative and metastasising one.
VENUTA, Federico, ANILE, MARCO, DISO, DANIELE, VITOLO, Domenico, RENDINA, Erino Angelo, DE GIACOMO, Tiziano, FRANCIONI, Federico, Giorgio Furio Coloni   +7 more
openaire   +2 more sources

Rac1 Deletion Causes Thymic Atrophy [PDF]

, 2011
The thymic stroma supports T lymphocyte development and consists of an epithelium maintained by thymic epithelial progenitors. The molecular pathways that govern epithelial homeostasis are poorly understood.
Glogauer Michael, Wright, Nick A, Geoff Laurent, Watt, FM, Janes, Sam M., Kristin M Braun, Emma Nye, Potton, E, Braun, Kristin M., Fiona M. Watt, Janes, Sam M, Katrina McNulty, Butler, Colin, Potton Elspeth, Glogauer, Michael, Wright, NA, Colin Butler, Benitah, Salvador Aznar, Potton, Elspeth, Aznar Benitah Salvador, Boyd, Richard, Jensen, K, Richard Boyd, Braun, Kristin M, Salvador Aznar Benitah, Butler Colin, Sam M Janes, Hunziker, L, Laurent, G, McNulty, Katrina, Elspeth Potton, Janes Sam M., Watt, Fiona M; id_orcid, Boyd, R, Nick A Wright, Kristin M. Braun, Nye, Emma, Laurent Geoff, Michael Glogauer, Wright Nick A., Nye, E, Butler, C, Braun, Kristin, Jensen Kim, Nye Emma, Wright, Nick A., McNulty, Ksatrina, Lukas Hunziker, Glogauer, M, McNulty Katrina, Sam M. Janes, Braun, KM, Laurent, Geoff, Hunziker Lukas, Watt, Fiona, Kim Jensen, Benitah, SA, Nick A. Wright, Watt Fiona M., McNulty, K, Boyd Richard, Fiona M Watt, Wright, Nick, Braun Kristin M., Watt, Fiona M., Jensen, Kim, Janes, SM, Hunziker, Lukas, Aznar Benitah, Salvador, Benitah, Salvador, Janes, Sam   +70 more
core   +1 more source

A Rare Case of Mediastinal Mass: Thymoma and Thymic Tumor [PDF]

, 2023
Thymomas and thymic carcinomas are rare mediastinal neoplasms arising from thymic epithelial cells, and the presence of synchronous or metachronous primary thymic neoplasms in a single patient is an extremely rare event.
Dias, Rita R, Baptista, Patrícia, Bertão, Manuela, Pichel, Rita C, Moura De Azevedo, Sofia, Rita C Pichel, Patrícia Baptista, Rita R Dias, Sofia Moura de Azevedo, Manuela Bertão   +9 more
core   +1 more source

Two Very Rare Cases of Metastatic Thymic Carcinoma with Sjogren’s Syndrome: A Case Series

Case Reports in Oncology, 2023
Thymic tumours are rare thoracic malignancies with thymic carcinoma accounting for approximately 12% of all thymic tumours compared to thymomas which account for approximately 86%.
Amy E. Smith, Alisa Kane, Francesca Watts, Min Qiu, Venessa Chin   +4 more
doaj   +1 more source

Case Report: Paraneoplastic psoriasis in thymic carcinoma

Frontiers in Oncology, 2023
Thymic carcinomas are exceedingly rare and very aggressive malignancies of the anterior mediastinum. While thymomas exhibit a high association with paraneoplastic syndromes, these phenomena are a rarity in thymic carcinomas.
Lucas Mix, Manuel Knoll, Max-Felix Häring, Wolfgang Andreas Bethge, Jan C. Schröder, Stephan Forchhammer, Patrick Krumm, Christian M. Schürch, Martin Schaller, Claudia Lengerke   +9 more
doaj   +1 more source

Characterization of the spatio-temporal dynamics in thymic epithelial development [PDF]

, 2015
The work presented in this thesis is centered on the development and maturation of the epithelial compartment in the murine thymus and consequently its functional capacity to promote normal thymopoiesis. Two main aspects have been investigated in depth:
Mayer, Carlos E.
core   +1 more source

Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden [PDF]

, 2011
BACKGROUND:The study exploits a natural human experimental model of subsistence farmers experiencing chronic and seasonally modified food shortages and infectious burden.
Ngom, Pa T, Solon Juan, Ngom Pa T, Andrew M Prentice, Morgan Gareth, Juan Solon, Prentice Andrew M, Richard Aspinall, Morgan, Gareth, Pa T Ngom, Prentice, Andrew M, Sophie E Moore, Aspinall, Richard, Gareth Morgan, Moore, Sophie E, Solon, Juan, Ngom, Pa T., Moore, Sophie E., Prentice, Andrew M., Aspinall Richard, Moore Sophie E   +20 more
core   +1 more source

Ectopic Thymic Carcinoma Located on The Dorsal Side of The Thyroid Gland

Ear, Nose & Throat Journal, 2023
Migration of the embryonic thymus is thought to be the basis for the formation of ectopic thymic tumors. Thymic ectopy may be a result of the abnormal migration of the third or fourth branchial cleft to the anterior mediastinum during weeks 5–6 of ...
Wei Wang BM, Jia-Ying Xu MM, Bo-Tao Zhang BM, Jun Jiang MD   +3 more
doaj   +1 more source

Heterogeneity in thymic emigrants: implications for thymectomy and immunosenescence. [PDF]

, 2013
The development of mature, antigen-inexperienced (naive) T cells begins in the thymus and continues after export into the periphery. Post-thymic maturation of naive T cells, in humans, coincides with the progressive loss of markers such as protein ...
Iren Bains (382649), Bains, Iren, Callard, Robin E., Andrew J Yates, Yates, AJ, Iren Bains, Yates, Andrew J., Robin E Callard, Callard, RE, Andrew J. Yates (195608), Robin E. Callard (382650), Bains, I   +11 more
core   +2 more sources