Results 161 to 170 of about 139,364 (204)

Current and Emerging Biologic Therapies for Severe Asthma. [PDF]

Drugs
Cazzola M, Matera MG, Ora J, Calzetta L, Rogliani P.   +4 more
europepmc   +1 more source

Beyond inflammation: alarmins as critical drivers of pulmonary fibrosis. [PDF]

ERJ Open Res
Pianigiani T, Dilroba A, Gambini C, Hernandez-Gonzalez F, d'Alessandro M, Bergantini L, Sellares J, Bargagli E, Cameli P.   +8 more
europepmc   +1 more source

Emerging Insights into the Inflammatory Phenotypes of Eosinophilic Esophagitis. [PDF]

J Inflamm Res
Nguyen ET, Furuta GT, Spencer LA, Dunn JLM.   +3 more
europepmc   +1 more source

Emerging immune networks and targeted strategies in T2 asthma. [PDF]

Front Immunol
Xi T, Zu T, Pang X, Wu F.
europepmc   +1 more source

The evaluation of cytokine profiles in atopic dermatitis patients treated with dupilumab: association with ocular complications. [PDF]

Front Immunol
Čelakovská J, Čermáková E, Boudkova P, Andrýs C.   +3 more
europepmc   +1 more source

Thymic stromal lymphopoietin (TSLP) is a substrate for tryptase in patients with mastocytosis

European Journal of Internal Medicine, 2023
Mastocytosis is a heterogeneous disease associated to uncontrolled proliferation and increased density of mast cells in different organs. This clonal disorder is related to gain-of-function pathogenic variants of the c-kit gene that encodes for KIT (CD117) expressed on mast cell membrane.
Simone Marcella, Angelica Petraroli, Luisa Canè, Anne Lise Ferrara, Remo Poto, Roberta Parente, Francesco Palestra, Leonardo Cristinziano, Luca Modestino, Maria Rosaria Galdiero, Maria Monti, Gianni Marone, Massimo Triggiani, Gilda Varricchi, Stefania Loffredo   +14 more
exaly   +6 more sources

Thymic stromal lymphopoietin (TSLP) and Toluene-diisocyanate-induced airway inflammation: Alleviation by TSLP neutralizing antibody

Toxicology Letters, 2019
Toluene-diisocyanate (TDI) is mainly used in the manufacturing process of polyurethane foams, and is a potent inducer of occupational asthma characterized by airway inflammation and airway hyperreactivity. Thymic stromal lymphopoietin (TSLP) plays an important role in the development of asthma, and correlating with the differentiation of Th2 and Th17 ...
Gongchang Yu, Martin Lavin, Bo Cunxiang   +2 more
exaly   +7 more sources

Tezepelumab. Anti-TSLP (thymic stromal lymphopoietin), Treatment of severe asthma

Drugs of the Future, 2021
Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine of the interleukin-2 (IL-2) cytokine family with both homeostatic and inflammatory properties in the human organism. Aberrant production of TSLP has been observed in several type 2 allergic disorders such as bronchial asthma, atopic dermatitis and allergic rhinitis, prompting the ...
Yao, Y., Ali, Z., Thomsen, S. F.
openaire   +3 more sources

Multiple Functions of the New Cytokine-Based Antimicrobial Peptide Thymic Stromal Lymphopoietin (TSLP) [PDF]

Pharmaceuticals, 2016
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine, hitherto mostly known to be involved in inflammatory responses and immunoregulation. The human tslp gene gives rise to two transcription and translation variants: a long form (lfTSLP) that is
Karl Schenck, Andreas Sonesson
exaly   +3 more sources

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Plasma thymic stromal lymphopoietin (TSLP) in adults with non-severe asthma: the EGEA study

Thorax, 2022
Thymic stromal lymphopoietin (TSLP), a cytokine involved in severe asthma treatment, was never studied in non-severe asthma.Among 969 adults from a large epidemiological study, cross-sectional analyses showed that plasma TSLP levels were associated with increased age and BMI, male sex, smoking and high TSLP levels (one IQR increase) with current asthma
Ibrahim, Bakari, Achour, Djamal, Zerimech, Farid, de Nadai, Patricia, Siroux, Valérie, Tsicopoulos, Anne, Matran, Régis, Granger, Vanessa, Nadif, Rachel   +8 more
openaire   +5 more sources