Results 1 to 10 of about 1,165 (92)
Biomedicines, 2021 Alarmins are innate cytokines, including thymic stromal lymphopoietin (TSLP), interleukin-33 (IL-33), and interleukin-25 (IL-25), which are mainly produced by airway epithelium and exert a prominent role in asthma pathobiology.
Corrado Pelaia +2 more
exaly +5 more sources
Role of Damage-Associated Molecular Patterns (DAMPs/Alarmins) in Severe Ocular Allergic Diseases
Cells, 2022 Severe ocular allergic diseases, such as atopic keratoconjunctivitis and vernal keratoconjunctivitis, cause severe allergic inflammation in the conjunctiva and corneal epithelial damage, resulting in visual disturbances. The involvement of damage (danger)
Ken Fukuda +2 more
exaly +4 more sources
Alarmins in Osteoporosis, RAGE, IL-1, and IL-33 Pathways: A Literature Review [PDF]
Medicina (Lithuania), 2020 Alarmins are endogenous mediators released by cells following insults or cell death to alert the host’s innate immune system of a situation of danger or harm.
Massimo De Martinis +2 more
exaly +4 more sources
The Role of Alarmins in the Pathogenesis of Rheumatoid Arthritis, Osteoarthritis, and Psoriasis
Current Issues in Molecular BiologyAlarmins are immune-activating factors released after cellular injury or death. By secreting alarmins, cells can interact with immune cells and induce a variety of inflammatory responses.
Kajetan Kiełbowski +2 more
exaly +4 more sources
Alarmins in Chronic Spontaneous Urticaria: Immunological Insights and Therapeutic Perspectives
BiomedicinesBackground: In the world, approximately 1% of the population suffers from chronic spontaneous urticaria (CSU), burdening patients’ quality of life and challenging clinicians in terms of treatment.
Angela Rizzi +2 more
exaly +4 more sources
Alarmins and c-Jun N-Terminal Kinase (JNK) Signaling in Neuroinflammation
Cells, 2020 Neuroinflammation is involved in the progression or secondary injury of multiple brain conditions, including stroke and neurodegenerative diseases.
Nina D. Anfinogenova +3 more
doaj +2 more sources
Alarmins, COVID-19 and comorbidities
Annals of Medicine, 2021 The coronavirus SARS-CoV-2, the aetiological agent of COVID-19 disease, is representing a worldwide threat for the medical community and the society at large so that it is being defined as “the twenty-first-century disease”.
Eleonora Di Salvo +4 more
doaj +2 more sources
Alarmins in autoimmune diseases
Autoimmunity Reviews, 2022 Alarmins are endogenous, constitutively expressed, chemotacting and immune activating proteins or peptides released because of non-programmed cell death (i.e.
Maria Giovanna Danieli +2 more
exaly +2 more sources
Medicina, 2022 Schizophrenia, consisting of a group of severe psychiatric disorders with a complex etiology, is a leading cause of disability globally. Due to the lack of objective indicators, accurate diagnosis and selection of effective treatments for schizophrenia ...
Huan Ma, Ning Cheng, Caiyi Zhang
doaj +2 more sources
Alarmins HMGB1, IL-33, S100A7, and S100A12 in Psoriasis Vulgaris
Mediators of Inflammation, 2020 Background. Psoriasis vulgaris is a chronic autoimmune disease associated with systemic inflammation. Increased levels of numerous cytokines, chemokines, growth factors, and other molecules were found in the skin and in the circulation of psoriatic ...
Pavel Borsky +10 more
doaj +2 more sources