Results 1 to 10 of about 550 (69)
Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells
Cells, 2020 Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the primary site of many infections, others are elicited in response to ...
Jonathan P Richardson +2 more
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Biomolecules, 2021 Psoriasis is a multifactorial pathology linked to systemic inflammation. Enhanced keratinocytes proliferation and a minor maturation state of the cells are typical features.
Marco Casciaro +2 more
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Biomolecules, 2023 Th2 inflammation is associated with various characteristics of patients with chronic obstructive pulmonary disease (COPD). In this study, we analyzed the COPD exacerbation risk associated with serum levels of interleukin (IL)-25/thymic stromal ...
Joon Young Choi +9 more
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Alarming and Calming: Opposing Roles of S100A8/S100A9 Dimers and Tetramers on Monocytes
Advanced Science, 2022 Mechanisms keeping leukocytes distant of local inflammatory processes in a resting state despite systemic release of inflammatory triggers are a pivotal requirement for avoidance of overwhelming inflammation but are ill defined.
Antonella Russo +19 more
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Cells, 2021 Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) family that is expressed in the nuclei of endothelial and epithelial cells of barrier tissues, among others.
Corinne Cayrol
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Frontiers in Oncology, 2021 ObjectivesTo investigate the role of interleukin-33 (IL-33) in head and neck squamous cell carcinoma (HNSCC).Materials and MethodsRNA-seq data of 520 cases of HNSCC were retrieved from The Cancer Genome Atlas. The tumor microenvironment was deconstructed
Liang Peng +8 more
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Alarmins and c-Jun N-Terminal Kinase (JNK) Signaling in Neuroinflammation
Cells, 2020 Neuroinflammation is involved in the progression or secondary injury of multiple brain conditions, including stroke and neurodegenerative diseases.
Nina D. Anfinogenova +3 more
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The GAR/RGG motif defines a family of nuclear alarmins
Cell Death and Disease, 2021 The nucleus is the target of autoantibodies in many diseases, which suggests intrinsic nuclear adjuvants that confer its high autoimmunogenicity. Nucleolin (NCL) is one abundant nucleolar autoantigen in systemic lupus erythematosus (SLE) patients and, in
Shan Wu +4 more
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Dual Immune Regulatory Roles of Interleukin-33 in Pathological Conditions
Cells, 2022 Interleukin-33 (IL-33), a member of the IL-1 cytokine family and a multifunctional cytokine, plays critical roles in maintaining host homeostasis and in pathological conditions, such as allergy, infectious diseases, and cancer, by acting on multiple ...
Han Guo +4 more
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Frontiers in Immunology, 2023 Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory cytokine, protecting the body from an uncontrolled immune response ...
Valentina Carlini +7 more
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