Results 41 to 50 of about 10,647 (207)

Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node

Cell Reports, 2017
The mechanism by which inflammation influences the adaptive response to vaccines is not fully understood. Here, we examine the role of lymph node macrophages (LNMs) in the induction of the cytokine storm triggered by inactivated influenza virus vaccine ...
Nikolaos Chatziandreou, Yagmur Farsakoglu, Miguel Palomino-Segura, Rocco D’Antuono, Diego Ulisse Pizzagalli, Federica Sallusto, Veronika Lukacs-Kornek, Mariagrazia Uguccioni, Davide Corti, Shannon J. Turley, Antonio Lanzavecchia, Michael C. Carroll, Santiago F. Gonzalez   +12 more
doaj   +1 more source

Alarmins and anti-alarmin biologics in asthma Astımda alarminler ve anti-alarmin biyolojikler

, 2018
Introduction: Alarmins are endogenous, constitutively expressed, chemotactic, and immune activating proteins/peptides that are released as a result of degranulation, cell injury or death, or in response to immune induction.
Görgülü, BEGÜM, Bavbek, Sevim
core   +1 more source

Serum calprotectin in nonsegmental vitiligo: a possible marker of disease activity

Journal of the Egyptian Women’s Dermatologic Society
Background Determining the status of nonsegmental vitiligo is crucial in initiating the management plan, especially when planning for surgery. Serum biomarkers can serve as an additive tool, to clinical examination and history-taking, in differentiating ...
Dalia A. Bassiouny, Yasmin B. El Zawahry, Ahmed M. Soliman, Alaa H. Sayed, Eman R. Youness, Dina G. Saadi   +5 more
doaj   +1 more source

S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll‐like receptor 4

EMBO Molecular Medicine, 2014
Members of the S100 protein family have been reported to function as endogenous danger signals (alarmins) playing an active role in tissue inflammation and repair when released from necrotic cells.
David Rohde, Christoph Schön, Melanie Boerries, Ieva Didrihsone, Julia Ritterhoff, Katharina F Kubatzky, Mirko Völkers, Nicole Herzog, Mona Mähler, James N Tsoporis, Thomas G Parker, Björn Linke, Evangelos Giannitsis, Erhe Gao, Karsten Peppel, Hugo A Katus, Patrick Most   +16 more
doaj   +1 more source

Extracellular Nucleophosmin Is Increased in Psoriasis and Correlates With the Determinants of Cardiovascular Diseases

Frontiers in Cardiovascular Medicine, 2022
We previously showed that genotoxic stress induced an active extracellular release of nucleophosmin (NPM) in human cardiac mesenchymal progenitor cells, and that serum deprivation provokes NPM secretion from human endothelial cells, eliciting ...
Marco D'Agostino, Sara Beji, Sara Sileno, Daniela Lulli, Laura Mercurio, Stefania Madonna, Corrado Cirielli, Sabatino Pallotta, Cristina Albanesi, Maurizio C. Capogrossi, Maurizio C. Capogrossi, Daniele Avitabile, Guido Melillo, Alessandra Magenta   +13 more
doaj   +1 more source

Epicutaneous Immunity and Onset of Allergic Diseases - Per-“Eczema”tous Sensitization Drives the Allergy March

Allergology International, 2013
Results: from recent epidemiological studies strongly suggest that ingestion of food promotes immune tolerance to food antigens, whereas exposure to food antigens through skin leads to allergic sensitization.
Kenji Matsumoto, Hirohisa Saito
doaj   +1 more source

Association Between Serum Alarmin Levels and Disease-specific Indices in Patients With Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

, 2021
Background/aim: We evaluated the relationship between serum alarmin levels and disease-specific indices in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Patients and methods: Sera and data from 79 patients were
조윤희, 안성수, 송정식, 이상원, 박용범   +4 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Supplementary Figure -Supplemental material for Fragmented hyaluronan has no alarmin function assessed in arthritis synovial fibroblast and chondrocyte cultures

, 2018
Supplemental material, Supplementary Figure for Fragmented hyaluronan has no alarmin function assessed in arthritis synovial fibroblast and chondrocyte cultures by Mia Olsson, Lisa Bremer, Cecilia Aulin and Helena Erlandsson Harris in Innate ...
Helena Erlandsson Harris (32049), Mia Olsson (227252), Lisa Bremer (5323145), Cecilia Aulin (5323142)   +3 more
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source