Results 21 to 30 of about 7,888 (200)
IL33/ST2 Axis in Diabetic Kidney Disease: A Literature Review
Medicina, 2019 Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues.
Alessandro Tonacci +2 more
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Alarmin Cytokines as Central Regulators of Cutaneous Immunity
Frontiers in Immunology, 2022 Skin acts as the primary interface between the body and the environment. The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults ...
Tatsuya Hasegawa +2 more
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TSLP and asthma: fellow travelers [PDF]
Exploration of Asthma & Allergy, 2023 The incidence of asthma, a heterogeneous inflammatory disease affecting over 300 million people worldwide, continues to increase in developed countries.
David El-Qutob, Antonio Letran
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Frontiers in Immunology, 2023 Over the past thirty years, the complexity of the αβ-T cell compartment has been enriched by the identification of innate-like T cells (ITCs), which are composed mainly of invariant natural killer T (iNKT) cells and mucosal-associated invariant T (MAIT ...
Aurélie Robin +11 more
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Alarmins from conjunctival fibroblasts up-regulate matrix metalloproteinases in corneal fibroblasts [PDF]
International Journal of Ophthalmology, 2020 AIM: To explore the effects of alarmins produced by necrotic human conjunctival fibroblasts on the release of matrix metalloproteinases (MMPs) by human corneal fibroblasts (HCFs).
Lin Chen +6 more
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Nuclear Alarmin Cytokines in Inflammation [PDF]
Journal of Immunology Research, 2020 Pathogen‐associated molecular patterns (PAMPs) are some nonspecific and highly conserved molecular structures of exogenous specific microbial pathogens, whose products can be recognized by pattern recognition receptor (PRR) on innate immune cells and induce an inflammatory response.
Lili Jiang +4 more
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Tumor necrosis factor is a necroptosis-associated alarmin
Frontiers in Immunology, 2022 Necroptosis is a form of regulated cell death that can occur downstream of several immune pathways. While previous studies have shown that dysregulated necroptosis can lead to strong inflammatory responses, little is known about the identity of the ...
Francesca Pinci +5 more
doaj +1 more source
Frontiers in Immunology, 2019 Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by mucosa damage associated with an uncontrolled inflammatory response. This immunological impairment leads to altered inflammatory mediators such as IL-33, which is shown to ...
Karen Dubois-Camacho +19 more
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Frontiers in Immunology, 2021 Ischemia and reperfusion injury is an early inflammatory process during liver transplantation that impacts on graft function and clinical outcomes. Interleukin (IL)-33 is a danger-associated molecular pattern involved in kidney ischemia/reperfusion ...
Louise Barbier +41 more
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Tumors Sound the Alarmin(s) [PDF]
Cancer Research, 2008 Abstract Recent evidence suggests that inflammatory molecules play critical roles in the development and progression of numerous tumors. However, one specific group of inflammatory molecules whose importance has been established in host immune responses, termed alarmins, has been largely overlooked in cancer biology.
Seth B, Coffelt, Aline B, Scandurro
openaire +2 more sources