Results 31 to 40 of about 10,647 (207)

Do advanced glycation end products contribute to food allergy?

Frontiers in Allergy, 2023
Sugars can bind non-enzymatically to proteins, nucleic acids or lipids and form compounds called Advanced Glycation End Products (AGEs). Although AGEs can form in vivo, factors in the Western diet such as high amounts of added sugars, processing methods ...
P. K. Smith, C. Venter, L. O’Mahony, R. Berni Canani, O. J. L. Lesslar   +4 more
doaj   +1 more source

Sector Alarmin hälytyskeskuksen evakuointi-suunnitelma [PDF]

, 2020
Sector Alarmin hälytyskeskuksen toiminta lukeutuu Sector Alarmin yrityksen ydintoimintoihin, jota pyritään ylläpitämään jokaisessa tilanteessa. Hälytyskeskuksen evakuointisuunnitelman avulla Sector Alarm pyrkii varmistamaan hälytyskeskuksen tuottamien ...
Kemppi, Savelij
core  

Pro-fibrogenic role of alarmin HMGB1 in HIV-HBV co-infection [PDF]

, 2023
OBJECTIVE: Liver disease is accelerated in people living with HIV (PLWH) with hepatitis B (HBV) coinfection. We hypothesised that liver fibrosis in HIV-HBV is triggered by increased hepatocyte apoptosis, microbial translocation and/or HIV/HBV viral ...
Avihingsanon, Anchalee, Otano, Itziar, Singh, Kasha P, Chen, Antony, Lewin, Sharon R, Pallett, Laura J, Duriez, Marion, Fusai, Giuseppe, Singh, Harsimran, Pinzani, Massimo, Maini, Mala K, Rombouts, Krista, Crane, Megan   +12 more
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Brain Cells Release Calreticulin That Attracts and Activates Microglia, and Inhibits Amyloid Beta Aggregation and Neurotoxicity

Frontiers in Immunology, 2022
Calreticulin is a chaperone, normally found in the endoplasmic reticulum, but can be released by macrophages into the extracellular medium. It is also found in cerebrospinal fluid bound to amyloid beta (Aβ).
Kyle M. Reid, Emily J. A. Kitchener, Claire A. Butler, Tom O. J. Cockram, Guy C. Brown   +4 more
doaj   +1 more source

Pro-fibrogenic role of alarmin high mobility group box 1 in HIV–hepatitis B virus coinfection

, 2022
20.500.12530/87852Liver disease is accelerated in people with HIV (PWH) with hepatitis B virus (HBV) coinfection. We hypothesized that liver fibrosis in HIV-HBV is triggered by increased hepatocyte apoptosis, microbial translocation and/or HIV/HBV viral ...
Singh, Kasha P, Chen, Antony, Pallett, Laura J, Fusai, Giuseppe, Kasha P. Singh, Massimo Pinzani, Harsimran Singh, Antony Chen, Itziar Otano, Mala K. Maini, Rombouts, Krista, Crane, Megan, Laura J. Pallett, Avihingsanon, Anchalee, Otano, Itziar, Marion Duriez, Sharon R. Lewin, Megan Crane, Lewin, Sharon R, Duriez, Marion, Giuseppe Fusai, Singh, Harsimran, Pinzani, Massimo, Anchalee Avihingsanon, Maini, Mala K, Krista Rombouts   +25 more
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IL-33 in Mental Disorders

Medicina, 2021
Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo, Giovanni Genovese, Marco Casciaro, Maria Rosaria Anna Muscatello, Antonio Bruno, Giovanni Pioggia, Sebastiano Gangemi   +6 more
doaj   +1 more source

Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca2+ signalling [PDF]

, 2023
Background Primary Sjogren's syndrome (pSS) is a systemic autoimmune disease that is embodied by the loss of salivary gland function and immune cell infiltration, but the mechanism(s) are still unknown.
Yuyang Sun, Brij B. Singh, Pooja Chauhan, Julian L. Ambrus, Chauhan, Arun, Bibhuti B. Mishra, Singh, Brij B, Viviane Nascimento Da Conceicao, Ambrus, Julian L, Frans G. M. Kroese, Madesh Muniswamy, Arun Chauhan, Pramod Sukumaran, Nascimento Da Conceicao, Viviane, Kroese, Frans G M, Mishra, Bibhuti B, Muniswamy, Madesh, Sukumaran, Pramod, Arjan Vissink, Vissink, Arjan; id_orcid, Chauhan, Pooja, Sun, Yuyang   +21 more
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Critical and diverse role of alarmin cytokines in parasitic infections

Frontiers in Cellular and Infection Microbiology
Alarmin cytokines including IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) function as danger signals to trigger host immunity in response to tissue injury caused by pathogenic factors such as parasitic infections.
Zhou Xing, Suiyi Liu, Xing He
doaj   +1 more source

First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

Cell Reports, 2017
From birth onward, the lungs are exposed to the external environment and therefore harbor a complex immunological milieu to protect this organ from damage and infection.
Simona Saluzzo, Anna-Dorothea Gorki, Batika M.J. Rana, Rui Martins, Seth Scanlon, Philipp Starkl, Karin Lakovits, Anastasiya Hladik, Ana Korosec, Omar Sharif, Joanna M. Warszawska, Helen Jolin, Ildiko Mesteri, Andrew N.J. McKenzie, Sylvia Knapp   +14 more
doaj   +1 more source

Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses

, 2019
Neuroimmune interactions have emerged as critical modulators of allergic inflammation, and type 2 innate lymphoid cells (ILC2s) are an important cell type for mediating these interactions.
Burkett, Patrick R., Schnell, Alexandra, Tsujikawa, Kazutake, Thakore, Pratiksha I., Vijay K. Kuchroo, Kazutake Tsujikawa, Kuchroo, Vijay K., Elena Christian, Pratiksha I. Thakore, Alexandra Schnell, Bruce D. Levy, Patrick R. Burkett, Raja-Elie E. Abdulnour, Lambden, Conner, Levy, Bruce D., Se-Jin Kim, Samantha J. Riesenfeld, Ramnik J. Xavier, Herbst, Rebecca H., Antonia Wallrapp, Riesenfeld, Samantha J., Conner Lambden, Regev, Aviv, Isaac M. Chiu, Abdulnour, Raja-Elie E., Chiu, Isaac M., Khan, Pavana, Wallrapp, Antonia, Kim, Se-Jin, Rebecca H. Herbst, Xavier, Ramnik J., Pavana Khan, Christian, Elena, Aviv Regev   +33 more
core   +1 more source