Results 181 to 190 of about 12,710 (220)

<i>Artemisia annua</i> Extract Ameliorates Atopic Dermatitis: Evidence from 3D Epidermal Model and Complementary in vitro Assays. [PDF]

J Exp Pharmacol
Tian Y, Jiao L, Li Y, Tian Y, Chen Y, Jia H, Ma L.   +6 more
europepmc   +1 more source

Botulinum Toxin A Modulates Keratinocyte Proliferation and Inflammatory and Pruritic Mediators in Wound Healing. [PDF]

Ann Dermatol
Jung D, Shin S, Kim KH, Kim KJ, Park EJ.
europepmc   +1 more source

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Tezepelumab. Anti-TSLP (thymic stromal lymphopoietin), Treatment of severe asthma

Drugs of the Future, 2021
Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine of the interleukin-2 (IL-2) cytokine family with both homeostatic and inflammatory properties in the human organism. Aberrant production of TSLP has been observed in several type 2 allergic disorders such as bronchial asthma, atopic dermatitis and allergic rhinitis, prompting the ...
Yao, Y., Ali, Z., Thomsen, S. F.
openaire   +2 more sources

Plasma thymic stromal lymphopoietin (TSLP) in adults with non-severe asthma: the EGEA study

Thorax, 2022
Thymic stromal lymphopoietin (TSLP), a cytokine involved in severe asthma treatment, was never studied in non-severe asthma.Among 969 adults from a large epidemiological study, cross-sectional analyses showed that plasma TSLP levels were associated with increased age and BMI, male sex, smoking and high TSLP levels (one IQR increase) with current asthma
Ibrahim, Bakari, Achour, Djamal, Zerimech, Farid, de Nadai, Patricia, Siroux, Valérie, Tsicopoulos, Anne, Matran, Régis, Granger, Vanessa, Nadif, Rachel   +8 more
openaire   +5 more sources

Thymic stromal lymphopoietin (TSLP) is a substrate for tryptase in patients with mastocytosis

European Journal of Internal Medicine, 2023
Mastocytosis is a heterogeneous disease associated to uncontrolled proliferation and increased density of mast cells in different organs. This clonal disorder is related to gain-of-function pathogenic variants of the c-kit gene that encodes for KIT (CD117) expressed on mast cell membrane.
Simone Marcella, Angelica Petraroli, Luisa Canè, Anne Lise Ferrara, Remo Poto, Roberta Parente, Francesco Palestra, Leonardo Cristinziano, Luca Modestino, Maria Rosaria Galdiero, Maria Monti, Gianni Marone, Massimo Triggiani, Gilda Varricchi, Stefania Loffredo   +14 more
openaire   +3 more sources

Thymic Stromal Lymphopoietin (TSLP) et marche atopique

Revue Française d'Allergologie, 2010
Resume La dermatite atopique (DA) est frequemment l’etape initiale d’une marche atopique (MA), comme l’indique le fait que plus de la moitie des patients souffrant d’une DA moderee a severe developpent ulterieurement un asthme. La DA et l’asthme partagent le meme phenotype atopique qui inclut notamment une inflammation de type T helper type 2 (Th2 ...
openaire   +1 more source

Thymic stromal lymphopoietin (TSLP) and Toluene-diisocyanate-induced airway inflammation: Alleviation by TSLP neutralizing antibody

Toxicology Letters, 2019
Toluene-diisocyanate (TDI) is mainly used in the manufacturing process of polyurethane foams, and is a potent inducer of occupational asthma characterized by airway inflammation and airway hyperreactivity. Thymic stromal lymphopoietin (TSLP) plays an important role in the development of asthma, and correlating with the differentiation of Th2 and Th17 ...
Gongchang Yu, Yu Zhang, Xiaoqun Wang, Linlin Sai, Cunxiang Bo, Abrey J. Yeo, Martin F. Lavin, Cheng Peng, Qiang Jia, Hua Shao   +9 more
openaire   +3 more sources

Thymic stromal lymphopoietin (TSLP) in naturally occurring asthma exacerbations in adults

3.2 Airway Cell Biology and Immunopathology, 2016
INTRODUCTION: TSLP is released from the airway epithelium in response to damage and is pivotal in orchestrating type 2 immune responses seen in allergic asthma. However, the role of TSLP in exacerbations of asthma has not been evaluated. AIM: We sought to investigate whether the epithelial damage associated with an asthma exacerbation would ...
Asger Bjerregård, Svetlana Baltic, Lucy Barrett, Phillip Thompson, Vibeke Backer, Markus Fally, Ingrid Laing, Siew-Kim Khoo, Peter Le Souëf, Celeste Porsbjerg   +9 more
openaire   +1 more source

Analysing disease-specific variants of thymic stromal lymphopoietin (TSLP) in asthma

3.2 Airway Cell Biology and Immunopathology, 2015
TSLP is a regulator of Th2 immune responses and is linked to allergic disease. TSLP has been shown to be up-regulated in the epithelium in severe asthma, but regulation of TSLP and its splice variants in bronchial fibroblasts (HBFs) is relatively unexplored. We tested the hypothesis that TSLP is expressed in HBFs in a disease severity-dependent manner.
Jessica Donaldson, David Smart, Emily Swindle, Matt Edwards, Peter Howarth, Donna E. Davies   +5 more
openaire   +1 more source

Thymic Stromal Lymphopoietin (TSLP)

Science-Business eXchange, 2013
Steven F. Ziegler, Florence Roan, Bryan D. Bell, Thomas A. Stoklasek, Masayuki Kitajima, Hongwei Han   +5 more
openaire   +2 more sources