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Choice of Capecitabine or S1 in Combination with Oxaliplatin based on Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase Expression Status in Patients with Advanced Gastric Cancer. [PDF]
J Gastric Cancer, 2019 Xu R +9 more
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II-87 大腸癌原発組織および転移組織周囲間質におけるthymidine phosphorylaseの免疫組織学的検討
, 1998 信弘 徳永 +11 more
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Multifunctional role of thymidine phosphorylase in cancer
Trends in Cancer, 2022Thymidine phosphorylase (TP) catalyzes the reversible phosphorolysis of thymidine, maintaining nucleoside homeostasis for DNA repair and replication. In many cancers TP is expressed at high levels and promotes thymidine catabolism, ultimately generating 2-deoxyribose (2dDR) that can support multiple procancer processes, including glycation of proteins,
Becka M. Warfield, Philip Reigan
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Current Medicinal Chemistry, 2023
Thymidine phosphorylase (TP), also referred to as "platelet-derived endothelial cell growth factor" is crucial to the pyrimidine salvage pathway. TP reversibly transforms thymidine into thymine and 2-deoxy-D-ribose-1-phosphate (dRib-1-P), which further ...
A. Murmu +4 more
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Thymidine phosphorylase (TP), also referred to as "platelet-derived endothelial cell growth factor" is crucial to the pyrimidine salvage pathway. TP reversibly transforms thymidine into thymine and 2-deoxy-D-ribose-1-phosphate (dRib-1-P), which further ...
A. Murmu +4 more
semanticscholar +1 more source