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PHOTOSENSITIZED DIMERIZATION OF THYMINE

Photochemistry and Photobiology, 1970
Abstract— In contrast with previous reports from other laboratories, four isomeric dimers were isolated from the photochemical reaction of thymine sensitized by either acetone or propiophenone. Product analyses, made by use of nuclear magnetic resonance spectroscopy, showed that the distribution of dimers is dependent on the character of the solvent ...
B H, Jennings   +2 more
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50 years thymine dimer

DNA Repair, 2008
Fifty years ago thymine dimer was discovered in the Biochemical and Biophysical Laboratory of Delft Technological University, The Netherlands, by one of the authors of this review (Beukers) as the first environmentally induced DNA lesion. It is one of the photoproducts formed between adjacent pyrimidine bases in DNA by UV irradiation, currently known ...
Beukers, R (Rudolf)   +2 more
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STRUCTURE OF A THYMINE‐THYMINE ADDUCT FORMED BY MENADIONE PHOTOSENSITIZATION

Photochemistry and Photobiology, 1993
Abstract— The structure of one of the dithymine adducts formed by near‐UV photosensitization of aqueous oxygenated thymine in the presence of 2‐methyl‐ 1, 4‐naphthoquinone is reported. The compound, 6′β‐hydroxy‐5′β‐1 ‐ [5‐methylpyrimidinyl‐ 2,4‐dione]‐5′‐6′‐dihydrothymine has one thymine ring (ring I) linked through the 1‐nitrogen atom to the C5′ atom ...
H, Katz, W, Stallings, J P, Glusker
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Determination of laser-induced thymine–thymine dimer in DNA by LC

Journal of Pharmaceutical and Biomedical Analysis, 2002
A new simple and selective high-performance liquid chromatography (HPLC) method has been developed for the determination of thymine-thymine (T-T) dimer in deoxyribonucleic acid (DNA) for the study of relationship between the yield of T-T dimer and laser irradiation conditions. The HPLC method is not disturbed by other hydrolysate formed in DNA with the
Lingxia, Zhang, Yuzhu, Hu
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DNA base stacking: The stacked uracil/uracil and thymine/thymine minima

Journal of Computational Chemistry, 2012
AbstractThe potential energy surfaces of stacked uracil dimer (U/U) and stacked thymine dimer (T/T) have been explored at the counterpoise (CP)‐corrected M06‐2X/6‐31+G(d) level of theory, in the gas phase and in solution (with water and, for U/U, 1,4‐dioxane as the solvents) modeled by a continuum solvent using the polarizable continuum model ...
Ruairidh S, Hunter, Tanja, van Mourik
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Quantitative extraction of thymine-thymine dimer from a large excess of thymine by preparative liquid chromatography

Journal of Chromatography A, 1989
Abstract Extremely small amounts of thymine-thymine dimer can be extracted from thymine solutions using overloaded elution and shaving a narrow fraction at the front of the overloaded, later eluting thymine band. A two- or three-step procedure, involving the concentration and reinjection of the collected fraction, permits the preparation of solutions
A.M. Katti, R. Ramsey, G. Guiochon
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Spectroscopic Evaluation of Novel Adenine/Thymine-Conjugated Naphthalenediimides: Preference of Adenine-Adenine over Thymine-Thymine Intermolecular Hydrogen Bonding in Adenine- and Thymine-Functionalized Naphthalenediimides

Journal of Fluorescence, 2019
The synthesis and spectroscopic characterization of novel nucleobase (adenine/thymine)-conjugated naphthalenediimides (NDIs), namely, NDI-AA, NDI-TT, and NDI-AT have been successfully achieved. NDI-AA, NDI-TT and NDI-AT have similar absorption in the 300-400 nm region.
Digambara, Patra   +6 more
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Selectivity for thymine over 5-bromouracil by a thymine-requiring bacterium

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
Abstract The relative incorporation of thymine and its analogue, 5-bromouracil, into the DNA of a thymine-requiring bacterium was studied under a variety of conditions. Exponentially growing cultures of Escherichia coli strain TAU-bar were transferred to media containing defined amounts of thymine and 5-bromouracil.
P, Hackett, P, Hanawalt
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Electronic Coupling Mediated by Stacked [Thymine-Hg-Thymine] Base Pairs

The Journal of Physical Chemistry B, 2006
Very recently it has been shown that stable metal-mediated base pairs [Thymine-Hg-Thymine] can form in DNA. To estimate the effect of such pairs on the efficiency of charge transfer through DNA, we carry out quantum mechanical calculations of double-stranded pi-stacks GXG, GXXG, and GXXXG, where X = [Thymine-Hg-Thymine] and stacks GT(n)G of canonical ...
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Radiation-induced Thymine Formation from Thymine Glycol

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1970
M, Namiki, T, Hayashi
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