Results 131 to 140 of about 91,729 (314)

Anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor GluR2 encephalitis in a myasthenia gravis patient with complete thymectomy: a case report

open access: yesBMC Neurology, 2019
Background Autoimmune encephalitis (AE) is a newly recognized autoimmune disorders in which the targets are proteins or receptors involved in synaptic transmission and neuronal excitability.
Qingyang Luo, Xianghong Wu, Wen Huang
doaj   +1 more source

Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]

open access: yes, 2019
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C   +5 more
core  

Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer

open access: yesExperimental Physiology, EarlyView.
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge   +10 more
wiley   +1 more source

Thymoma-associated T-cell immunodeficiency after radiotherapy: A case report

open access: yesRespiratory Medicine Case Reports, 2021
Acquired immunodeficiency in thymoma (Good's syndrome) without hypogammaglobulinemia is a rare condition. Here we describe the case of a 29-year-old Japanese woman with thymoma-associated T cell immunodeficiency after radiation therapy.
Kensuke Nakagawara   +13 more
doaj  

High CTLA-4 expression correlates with poor prognosis in thymoma patients

open access: yesOncoTarget, 2018
Thymomas, tumors that arise from epithelial cells of the thymus gland, are the most common neoplasms of the anterior mediastinum, with an incidence rate of approximately 2.5 per million/year.
G. Santoni   +13 more
semanticscholar   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi   +5 more
wiley   +1 more source

Thymoma geassocieerde exfoliatieve dermatitis bij een kat [PDF]

open access: yes, 2012
A 10-year-old male castrated European Shorthair was presented with signs of scaling, alopecia and pruritus. The dermatopathological examination demonstrated an interface dermatitis with a few apoptotic keratinocytes, a mural lymphocytic folliculitis and ...
Bosmans, Tim   +6 more
core   +1 more source

Mediastinal neoplasms in patients with Graves disease: a possible link between sustained hyperthyroidism and thymic neoplasia? [PDF]

open access: yes, 2012
Background Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism.
Boyd, Jonathan D, Juskevicius, Ridas
core   +2 more sources

Multi‐omics profiling identifies TNFRSF18 as a novel marker of exhausted CD8⁺ T cells and reveals tumour‐immune dynamics in colorectal cancer

open access: yesClinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Schematic model for TNFRSF18 decline fuels stemness‐driven immune evasion in colorectal cancer. Tumour cells with upregulated stemness‐related ribosomal proteins (RPS7/RPL30/RPL8) evade TNF‐mediated clearance. This TNFRSF18‐stemness axis forms a feed‐forward loop that promotes immune escape, representing a potential therapeutic target for CRC. Abstract
Tengfei Jia   +6 more
wiley   +1 more source

Long-term prognosis in patients with thymoma combined with myasthenia gravis: a propensity score-matching analysis

open access: yesFrontiers in Medicine
IntroductionWe aimed to assess the impact of myasthenia gravis (MG) on the long-term prognosis in patients with thymoma after surgery and identify related prognostic factors or predictors.MethodsThis retrospective observational study included 509 ...
Kai Zhao   +11 more
doaj   +1 more source

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