Results 131 to 140 of about 91,729 (314)
Background Autoimmune encephalitis (AE) is a newly recognized autoimmune disorders in which the targets are proteins or receptors involved in synaptic transmission and neuronal excitability.
Qingyang Luo, Xianghong Wu, Wen Huang
doaj +1 more source
Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C+5 more
core
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge+10 more
wiley +1 more source
Thymoma-associated T-cell immunodeficiency after radiotherapy: A case report
Acquired immunodeficiency in thymoma (Good's syndrome) without hypogammaglobulinemia is a rare condition. Here we describe the case of a 29-year-old Japanese woman with thymoma-associated T cell immunodeficiency after radiation therapy.
Kensuke Nakagawara+13 more
doaj
High CTLA-4 expression correlates with poor prognosis in thymoma patients
Thymomas, tumors that arise from epithelial cells of the thymus gland, are the most common neoplasms of the anterior mediastinum, with an incidence rate of approximately 2.5 per million/year.
G. Santoni+13 more
semanticscholar +1 more source
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi+5 more
wiley +1 more source
Thymoma geassocieerde exfoliatieve dermatitis bij een kat [PDF]
A 10-year-old male castrated European Shorthair was presented with signs of scaling, alopecia and pruritus. The dermatopathological examination demonstrated an interface dermatitis with a few apoptotic keratinocytes, a mural lymphocytic folliculitis and ...
Bosmans, Tim+6 more
core +1 more source
Mediastinal neoplasms in patients with Graves disease: a possible link between sustained hyperthyroidism and thymic neoplasia? [PDF]
Background Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism.
Boyd, Jonathan D, Juskevicius, Ridas
core +2 more sources
Schematic model for TNFRSF18 decline fuels stemness‐driven immune evasion in colorectal cancer. Tumour cells with upregulated stemness‐related ribosomal proteins (RPS7/RPL30/RPL8) evade TNF‐mediated clearance. This TNFRSF18‐stemness axis forms a feed‐forward loop that promotes immune escape, representing a potential therapeutic target for CRC. Abstract
Tengfei Jia+6 more
wiley +1 more source
IntroductionWe aimed to assess the impact of myasthenia gravis (MG) on the long-term prognosis in patients with thymoma after surgery and identify related prognostic factors or predictors.MethodsThis retrospective observational study included 509 ...
Kai Zhao+11 more
doaj +1 more source