The role of regulatory B cell/T follicular helper cell balance in thymoma and thymoma-associated myasthenia gravis [PDF]
Thymoma is often associated with myasthenia gravis (MG). Abnormal lymphocyte differentiation often occurs in the thymoma tumor microenvironment (TME), leading to thymoma-associated autoimmune diseases.
Peng Zhang +12 more
doaj +2 more sources
Good’s syndrome revealed by recurrent sigmoid diverticulitis [PDF]
Thymus is a primary lymphoid organ whose main function is the education of the T lymphocytes. Thymoma is uncommon neoplasia derived from epithelial cells of the thymus. Patients with thymoma frequently present with autoimmune disorders, mostly myasthenia
Hassene Attout +4 more
doaj +2 more sources
Downregulation of HMGB1 in thymoma cells affects T cell differentiation
Introduction: Thymoma is the most common anterior mediastinal tumor and is closely associated with myasthenia gravis (MG). Our previous study showed that the expression of Th17 cells increased and the expression of Treg decreased in MG-associated thymoma
Jian Li +5 more
doaj +1 more source
Case Report: MDM4 Amplified in a Thymoma Patient With Autoimmune Enteropathy and Myocarditis
IntroductionThymoma is a type of mediastinal malignant tumors which always associated with autoimmune diseases. Although surgery is the predominant treatment method for thymoma, the pathogenesis of thymoma and thymoma-associated autoimmune diseases is ...
Xin Du +6 more
doaj +1 more source
YAP1-MAML2 Fusion as a Diagnostic Biomarker for Metaplastic Thymoma
BackgroundMetaplastic thymoma is a very rare tumor with only a few case reports documented in literature. Hence, its molecular features have not been well explored.Material and MethodsSeventeen specimens of metaplastic thymoma were sequenced and ...
Jikai Zhao +5 more
doaj +1 more source
Coexistence of Thymus and Colon Adenocarcinoma: A Case Report
Thymoma is a very rare tumor with a rate of 1.7 per million. Thymoma often occurs between the ages of 35-70. Thymoma is frequently located in the anterior mediastinum. Patients with thymoma often do not cause symptoms clinically.
Muhammed Selim Bodur +8 more
doaj +1 more source
Good's Syndrome Presenting With Weaning Failure From Ventilation and Myasthenia Gravis in a Post-Thymectomy Patient. [PDF]
This case highlights the importance of long‐term vigilance in patients with thymoma, even after apparently successful resection, as Good's syndrome may manifest years later. Clinicians should maintain a high index of suspicion for Good's syndrome in any thymectomized patient presenting with unexplained infections, diarrhoea, or autoimmune complications,
Mehta AA +4 more
europepmc +2 more sources
Identification of differentially expressed circular RNAs associated with thymoma
Background Thymomas and thymic carcinomas are the most common tumor types among anterior mediastinal lesions. However, the relationship between molecular aberrations and thymoma patients are poorly understood, especially abnormal changes in the ...
Qingjun Wu +8 more
doaj +1 more source
Viral infection in thymoma and thymic tumors with autoimmune diseases
A thymoma is a type of thymic tumor which is rarely malignant that is frequently reported in adult patients. A number of thymoma‐related immune disorders are observed including autoimmune diseases, which suggests a strong connection between thymoma ...
Rui Chang +3 more
doaj +1 more source
ObjectivesAccurate histological typing plays an important role in diagnosing thymoma or thymic carcinoma (TC) and predicting the corresponding prognosis.
Huaqi Zhang +7 more
doaj +1 more source

