Results 51 to 60 of about 305,149 (190)

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Treatment of Recurrent Thymoma

open access: yesChinese Journal of Lung Cancer, 2020
Thymoma is a potential malignant disease with a recurrence rate of 10% to 30% after complete resection. There is no agreement on the treatment strategy and standard for recurrent thymoma.
Xianping LIU, Xiao LI, Jianfeng LI
doaj   +1 more source

Diagnostic Utility of PET CT in Thymic Tumours with Emphasis on 68Ga-DOTATATE PET CT in Thymic Neuroendocrine Tumour - Experience at a Tertiary Level Hospital in India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Introduction:18 Fluorine-fluoro-2-deoxyglucose positron emission tomography/computed tomography (18F- FDG-PET/CT) is of importance in assessing high-risk thymoma and thymic carcinomas.
Julie Hephzibah   +2 more
doaj   +1 more source

An unusual location of micronodular thymoma with lymphoid stroma: A posterior mediastinal mass invading into pleura

open access: yesHuman Pathology Reports, 2023
Micronodular thymoma with lymphoid stroma (MNTL) is a rare type of thymoma that is often found alongside Type A thymoma. Here, we present a case of MNTL diagnosed in an 82 year-old-female who had a thymus excision seven years prior.
Utku Ekin   +3 more
doaj   +1 more source

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

open access: yesAdvanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche   +21 more
wiley   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

open access: yesAdvanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim   +16 more
wiley   +1 more source

Myelodysplasia followed by Good's Syndrome: A unique manifestation associated with thymoma

open access: yesKaohsiung Journal of Medical Sciences, 2012
Good’s syndrome, also known as thymoma with combined immunodeficiency, is rare. The immunodeficiency may precede, arise concurrently with or follow the diagnosis of thymoma.
Ling-Ping Chen   +5 more
doaj   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Computed Tomography differential features of Anterior Mediastinal Thymoma and Lymphoma

open access: yesInternational Journal of Endorsing Health Science Research, 2017
Background: To identify the CT features of anterior mediastinal thymoma and lymphoma and evaluate CT findings that may help in suggesting specific diagnosis among these tumors.
Sagar Thapa   +5 more
doaj   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo   +10 more
wiley   +1 more source

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