Results 81 to 90 of about 314,952 (197)
Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang +4 more
wiley +1 more source
The treatment of thymic epithelial tumors (TETs) in children may pose a serious problem. This is because thymic tumors—thymomas and thymic carcinomas, are extremely rare in patients of this age group, and thus a consistent treatment scheme has not been established.
openaire +2 more sources
ABSTRACT To evaluate the feasibility and safety of median sternotomy combined with hemi‐clamshell thoracotomy for resection of extremely large intrathoracic tumors. The perioperative data of three patients with large tumors in the thoracic cavity from January 2021 to December 2024 were collected and analyzed retrospectively, and median sternotomy ...
Xiaoyun Li +3 more
wiley +1 more source
TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang +8 more
wiley +1 more source
Non‐Cyclic Rozanolixizumab Administration in Complex Generalized Myasthenia Gravis
ABSTRACT Introduction/Aims Rozanolixizumab, an inhibitor of the neonatal Fc receptor (FcRn), is used to treat patients with generalized myasthenia gravis (gMG) refractory to standard therapies. However, the approved six‐week cyclic regimen may be associated with a “wearing‐off” effect and disease fluctuations. We evaluated the non‐cyclic administration
Marc Abi Aoun +6 more
wiley +1 more source
Thymoma masquerading as transfusion dependent anemia
Pure red cell aplasia (PRCA) is a known entity in clinical medicine. Patients are often transfusion dependent for their whole life. Ascertaining its etiology is always a herculean task.
Javvid Muzamil +5 more
doaj +1 more source
In this case of a complex post‐surgical PAL after radical thymectomy, lobectomy and pleurectomy, we describe how sequential bronchoscopic balloon catheter occlusion with the aid of a digital chest drain allowed physiological localization of an air leak predominantly originating from the LB6 lateral subsegment.
Ivory Ching Yee Yeo +2 more
wiley +1 more source
In the field of rare diseases, where high‐quality evidence remains limited, this study demonstrated how controversial treatment practices are managed in real‐world settings on a nationwide scale. The proportion of anthracycline‐based chemotherapy for stage IV thymoma increased from 50.0% in 2018 to 77.8% in 2022.
Junichi Ishigaki +3 more
wiley +1 more source
Background Autoimmune encephalitis (AE) is a newly recognized autoimmune disorders in which the targets are proteins or receptors involved in synaptic transmission and neuronal excitability.
Qingyang Luo, Xianghong Wu, Wen Huang
doaj +1 more source
A case of canine urothelial carcinoma of the urinary bladder with skull and skeletal metastases
Canine urinary bladder neoplasia is uncommon, representing less than 1% of canine neoplasms. Amongst cases of urinary bladder neoplasia in dogs, primary urothelial carcinoma is the most frequent. Urothelial carcinomas are malignant invasive tumours which tend to be slow growing and metastasise late.
A Teh, T Sima, E Shinozaki, R Malik
wiley +1 more source

