Results 221 to 230 of about 208,657 (313)

Single-cell RNA-sequencing of myasthenia gravis reveals transcriptional heterogeneity and dysfunction of immune cell populations. [PDF]

Int Immunol
Wu Q, Guo Y, Zhou L, Tian Y, Yu H, Zhou T, Yin S, Zou L.   +7 more
europepmc   +1 more source

CD68 and F4/80 Markers Demonstrate Inflammatory Synergism Between Apical Periodontitis and Liver Fibrosis in Wistar Rats

International Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti, C. Cantiga‐Silva, M. P. Justo, P. H. C. Oliveira, F. D. Faria, J. Goto, E. Ervolino, G. Sivieri‐Araújo, T. N. Pinheiro, L. T. A. Cintra   +9 more
wiley   +1 more source

Intrathyroidal thymic tissue: a pediatric case series from a secondary care center. [PDF]

Ann Pediatr Endocrinol Metab
Pereira RS, Silva JA, Dias MI, Simões AM, Pereira SM, Martins V.   +5 more
europepmc   +1 more source

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Effects of Timing of Microbial Exposure on Microbiome Assembly and Amphibian Immune Development. [PDF]

Ecol Evol
Miller AJ, Jo MC, Hui CK, Petereit J, Woodhams DC, Voyles J.   +5 more
europepmc   +1 more source

Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance

Immunology, EarlyView.
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos, Vitor Marcel Faça, Eduardo Antonio Donadi, Ana Paula Masson, Carlos Crippa Coletto, Gustavo Ronconi Roza   +5 more
wiley   +1 more source

Analysis of Human Thymopoiesis Reveals Rapid Postnatal Remodeling of Thymocytes Within the First 3 Months of Life. [PDF]

Eur J Immunol
Kergaravat C, Doisne JM, Godard C, Cieslak A, Amrane M, Vermijlen D, Asnafi V, Benlagha K, Santo JPD, Clave E, Toubert A.   +10 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Impact of Chronic Infection-Induced Inflammation on TREG Cell Homeostasis. [PDF]

Eur J Immunol
Lanzar ZR, Aldridge DL, Eberhard JN, Cruz-Morales E, Conway IO, Bunkofske ME, Pereira JA, Parker M, Kanellopoulou C, Hunter CA.   +9 more
europepmc   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

Plant, Cell &Environment, EarlyView.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee, Madhabi Das, Sanjib Patra, Srijib Chatterjee, Amit Roy, Arunava Mandal   +5 more
wiley   +1 more source