Results 81 to 90 of about 136,384 (208)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Immunohistochemical Biomarkers of Gastrointestinal, Pancreatic, Pulmonary, and Thymic Neuroendocrine Neoplasms.

, 2018
Neuroendocrine neoplasms (NENs) are a heterogeneous group of epithelial neoplastic proliferations that irrespective of their primary site share features of neural and endocrine differentiation including the presence of secretory granules, synaptic-like ...
Papotti, M., La Rosa, S., Volante, M., Uccella, S.   +3 more
core   +2 more sources

Timoma, a propósito de un caso

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Los timomas constituyen una neoplasia poco común, derivada de las células epiteliales del timo, y representan menos del uno por ciento de los cánceres en el adulto.
Dagoberto Calderón-Rodríguez, Tomás Díaz-Llaudy, Vladimir Reyes-Amado   +2 more
doaj  

Elucidating the Role of the T Cell Receptor Repertoire in Myelodysplastic Neoplasms and Acute Myeloid Leukemia

Diseases
T cells, as integral components of the adaptive immune system, recognize diverse antigens through unique T cell receptors (TCRs). To achieve this, during T cell maturation, the thymus generates a wide repertoire of TCRs.
Georgios Petros Barakos, Vasileios Georgoulis, Epameinondas Koumpis, Eleftheria Hatzimichael   +3 more
doaj   +1 more source

Atypical Carcinoid Tumor of the Thymus: A Rare Case Report

Neuroendocrine tumors (NETs) of the thymus are exceedingly unusual neoplasms, accounting for approximately 0.4% of all carcinoid tumors and less than 5% of all the anterior mediastinal neoplasms.
H. V. Shubha, B. V. Suguna, C. Vijaya, N. S. Sharanya   +3 more
core   +1 more source

Cystic Lesions of the Pancreas [PDF]

, 2014
With the increasing use of abdominal imaging, cystic lesions of the pancreas are being more frequently detected. These lesions may carry a significant premalignant potential.
Azzopardi, Neville
core  

Purpurin Alleviates Chemotherapy‐Induced Thrombocytopenia Through Estrogen Receptor α Dependent Phosphoinositide 3‐Kinase/Protein Kinase B Signalling

Phytotherapy Research, EarlyView.
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan, Xinle Wang, Lu Hao, Xiaoqin Tang, Zhixuan Liu, Long Wang, Xiang Xie, Xiang Li, Chunling Zhao, Yan Li, Xinwu Huang, Yuanzhi Liu, Jianming Wu   +12 more
wiley   +1 more source

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source

Rare neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Valentina Ciaravino, CIARAVINO, VALENTINA, Roberto Malagò, MALAGO', Roberto, Roberto Pozzi Mucelli, Capelli, Paola, Paola Capelli, DE ROBERTIS LOMBARDI, Riccardo, PEDICA, Federica, Riccardo De Robertis, Federica Pedica, POZZI MUCELLI, Roberto   +11 more
core   +1 more source

In Vitro and In Vivo Immunomodulatory and Protective Effects of Leukemia Inhibitory Factor‐Engineered Mesenchymal Stromal Cells in Experimental Endotoxemia

Microbiology and Immunology, EarlyView.
ABSTRACT Sepsis is a life‐threatening condition characterized by dysregulated systemic inflammation and high mortality rates. Mesenchymal stem/stromal cells (MSCs) have emerged as promising immunomodulatory agents; however, genetic engineering strategies can enhance their therapeutic efficacy.
Alana Costa de Oliveira, Diego de Carvalho Carneiro, Luiza Carolina França Opretzka, Breno Cardim Barreto, Dahara Keyse Carvalho Silva, Girlaine Café Santos, Cássio Santana Meira, Milena Botelho Pereira Soares   +7 more
wiley   +1 more source