Results 61 to 70 of about 37,446 (289)

Congenital thymoma

Autopsy and Case Reports, 2021
Thymomas are a heterogeneous group of tumors arising from the epithelium of the thymus. They are categorized by the proportion of neoplastic epithelia to lymphocytes and by the degree of cytologic atypia.
Momal Tara Chand, Jacob Edens, Tayson Taixin Lin, David Goshorn, Truc Pham   +4 more
doaj  

Gastrointestinal tract carcinoid with carcinoid syndrome in 63-year-old diver – a case report

Journal of Education, Health and Sport, 2023
Introduction: Carcinoid is a tumor that originates from neuroendocrine cells.[1] It was primarily named and described in 1907 by Siegfried Oberndorfer to characterize neoplasms located in GIST with a relatively indolent course.[2] Term “carcinoid” is ...
Hanna Dominik, Wojciech Pawęska, Barbara Dominik   +2 more
doaj   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Myasthenia gravis and lymphoblastic lymphoma involving the thymus: A rare association

, 2001
Myasthenia gravis (MG) is an autoimmune neuromuscular junction disease. An association between thymic epithelial neoplasms and MG is well known. However, it is rarely associated with hematologic malignancies.
Abali, H, Tan, E, Guler, N, Uner, AH, Ruacan, E, Gullu, İBRAHİM HALİL, Engin, H, Altundag, K, Akyol, A   +8 more
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

A rare case of tumor‐to‐tumor metastasis from thymic carcinoma to an ovarian mature teratoma

Thoracic Cancer
Metastasis from one neoplasm to another is referred to as tumor‐to‐tumor metastasis (TTM). TTM is rarely observed. Here, we present a patient with TTM from a thymic carcinoma to an ovarian mature teratoma. A 25‐year‐old woman, diagnosed with unresectable
Tsuyoshi Sasada, Chigusa Shirakawa, Ryo Tachikawa, Daisuke Yamashita, Keisuke Tomii   +4 more
doaj   +1 more source

Aspects of thymic pathologies in paediatric patients. Case study of true thymic hyperplasia and the diagnostic approach

Pediatria Polska
Proliferative lesions of the thymus are very rare in children and represent about 2% of mediastinal tumours. They may result from organ hyperplasia, the presence of cysts, or germinal and epithelial neoplasms.
Aleksandra Wietecha-Pikul, Agnieszka Juranek, Ewa Cichocka-Jarosz, Izabella Głodzik, Wojciech Górecki, Edyta Juraszewska, Aleksandra Kiszka-Wiłkojć, Grzegorz Lis, Anna Taczanowska-Niemczuk, Przemko Kwinta   +9 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Primary Mesenteric Carcinoid Tumor Presenting with Carcinoid Syndrome

Case Reports in Gastroenterology, 2018
Neuroendocrine neoplasms (NENs) are a diverse group of tumors arising throughout the body with a common origin from neuroendocrine cells. Well-differentiated NENs, also known as neuroendocrine tumors (NETs), are generally indolent and are often found ...
Oluwaseun Shogbesan, Abdullateef Abdulkareem, Binu Pappachen, John Altomare   +3 more
doaj   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source