Results 41 to 50 of about 45,869 (266)
T-lymphocyte-rich thymoma and myasthenia gravis in a Siberian tiger (Panthera tigris altaica) [PDF]
, 2014 A 10-year-old captive male Siberian tiger (Panthera tigris altaica) presented with acute onset collapse, vomiting and dyspnoea, preceded by a 6-month period of progressive muscle wasting.A. Routh, Allen, Aronsohn, Blaies, Brandes, C. Lamm, Day, Dewey, Ecco, Hadlow, ISIS, Jacobs, K. Allan, K. Berry, Kang, Kenny, King, Kunzel, Marx, N. Masters, Pye, Ramos-Vara, S. Rivers, Schwartz, Scudamore, Shelton, Shelton, Suster, Travis, Valli, Wallace, Walsh +31 morecore +1 more sourceGeneration of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung +10 morewiley +1 more sourceSubxyphoid thoracoscopic thymectomy in a patient with the location of the left brachiocephalic vein in the thickness of a cystically altered thymus gland: clinical observation and literature review
Клинический разбор в общей медицинеThymic neoplasms are rare in prevalence among the general population. The most common benign formation of the anterior mediastinum is thymus cyst, while thymoma is the most common malignant tumor of the mediastinum.Zavir M. Salimov, Andrey B. Riabov, Andrey B. Riabov, Andrey B. Riabov, Grigoriy V. Afonin, Vitaliy Yu. Skoropad, Tatev A. Аgababyan, Ekaterina I. Kupriyanova, Anastasiya S. Yakusheva, Vladimir A. Petrov, Vladimir A. Petrov, Sergey А. Ivanov, Sergey А. Ivanov, Andrey D. Kaprin, Andrey D. Kaprin, Andrey D. Kaprin +15 moredoaj +1 more sourceIndirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen. [PDF]
, 1987 The transmission of a lymphomagenic agent(s) from the bone marrow of irradiated mice to thymic target cells has been demonstrated by: (a) the induction of T cell lymphomas in nonirradiated thymic grafts implanted in irradiated, Thy-l-congenic mice, (b ...Hansteen, GA, Lieberman, M, McCune, JM, Scott, ML, Weissman, IL, White, JH +5 morecore The transcriptional activator Gli2 modulates T-cell receptor
signalling through attenuation of AP-1 and NFκB activity [PDF]
, 2015 Different tissues contain diverse and dynamic cellular niches, providing distinct signals to tissue-resident or migratory infiltrating immune cells.Agathocleous, Alcedo, Aza-Blanc, Bai, Bellavia, Boyman, Brennan, Buckland, Chan, Cheng, Crompton, D'Acquisto, de la Roche, Decker, Dennler, Drakopoulou, El Andaloussi, Feske, Finetti, Furler, Furmanski, Furmanski, Gilmour, Hafezi-Moghadam, Hager-Theodorides, Hager-Theodorides, Hatayama, Huang, Hui, Huse, Ingham, Jiang, Kahn, Kasper, Kim, Kumabe, Lau, Le, Lee, Li, Lowrey, Marigo, Matise, Medyouf, Michel, Mo, Neumann, Nielsen, Outram, Park, Perry, Pola, Priatel, Priatel, Reynolds, Riobó, Rohatgi, Rowbotham, Rowbotham, Rowbotham, Sacedón, Sacedón, Sato, Seo, Shah, Shimizu, Smith, Smith-Garvin, Stewart, Thompson, Varjosalo, Wakelin, Yamane +72 morecore +5 more sourcesZebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty +4 morewiley +1 more sourceITALIAN CANCER FIGURES - REPORT 2015: The burden of rare cancers in Italy = I TUMORI IN ITALIA - RAPPORTO 2015: I tumori rari in Italia [PDF]
, 2016 OBJECTIVES:
This collaborative study, based on data collected by the network of Italian Cancer Registries (AIRTUM), describes the burden of rare cancers in Italy.Adamo, Ms, Adorni, A, Alessi, D, Aletta, P, Amendola, V, Amodio, R, Amodio, Rosalba, Andreone, S, Angelin, T, Anghinoni, E, Annulli, Ml, Autelitano, M, Balducci, C, Baracco, M, Baracco, S, Barale, A, Barchielli, A, Battisti, W, Bella, F, Bella, Francesca, Bellatalla, C, Bellini, A, Belluardo, C, Benatti, P, Benedetto, G, Benfatto, L, Bernazza, E, Bianconi, F, Biavati, P, Bidoli, E, Birri, S, Bizzoco, S, Bizzoco, Sabrina, Bonini, A, Borciani, E, Bordini, M, Bovo, E, Bozzani, F, Braghiroli, B, Brosio, F, Brucculeri, Ma, Brunori, V, Bucalo, G, Bucchi, L, Bugliarello, E, Bulatko, A, Busco, S, Busco, Susanna, Busso, P, Buzzoni, C, Buzzoni, C., Buzzoni, Carlotta, Caiazzo, Al, Calabrese, A, Calabretta, L, Caldarella, A, Candela, G, Cannone, G, Canu, L, Caparelli, M, Cappelletti, M, Caprara, L, Carletti, N, Caroli, S, Cascio, Ma, Cascone, G, Casella, C, Casella, C, Cassetti, Tiziana, Castaing, M, Castaing, Marine, Cavalieri d'Oro, L, Cavallo, R, Cecconami, L, Celesia, Mv, Cena, T, Cercato, Mc, Cesaraccio, R, Chiesa, R, Cirilli, C, Cirilli, Claudia, Cocchioni, M, Codazzi, T, Cogno, R, Colamartini, A, Colavolpe, Af, Cometti, I, Contiero, P, Contrino, Ml, Corbinelli, A, Cordaro, C, Corti, M, Costa, A, Costarelli, D, Coviello, V, Crapanzano, G, Crocetti, Emanuele, Cuccaro, F, Curatella, S, Cusimano, R, Cusimano, Rosanna, D'Alessandro, A, D'Alò, D, Dal Cin, A, Dal Maso, L, Dal Maso, Luigino, Davini, C, De Angelis, Roberta, De Dottori, M, De Maria, V, De Santis, E, De Valiere, E, Dei Tos, Ap, Demurtas, G, Devigili, E, Di Dia, Pp, Di Felice, E, di Grazia, L, Di Gregorio, C, Di Norcia, R, Di Prima, A, Dinaro, Y, Distefano, R, Doa, N, Domati, F, Donini, M, Fabiano, S, Facchinelli, G, Faccini, F, Falcini, F, Falk, M, Fanetti, Ac, Fattoruso, S, Fedele, M, Ferrari, F, Ferretti, S, Fidelbo, M, Filiberti, Ra, Filipazzi, L, Fiore, Ar, Forgiarini, O, Frasca, G, Frassoldi, E, Fusco, M, Fusco, M, Fusco, Mario, Gabbi, C, Gada, D, Garrone, E, Gatta, Gemma, Gatti, L, Gennaro, V, Gennaro, Valerio, Gentilini, Ma, Gerevini, C, Germinetti, F, Ghilardi, S, Ghisleni, S, Giacomin, A, Giacomin, Adriano, Giavazzi, L, Gilardi, F, Giorgetti, S, Giorgi Rossi, Paolo, Giubelli, C, Giuliani, O, Giurdanella, Mc, Gola, G, Goldoni, Ca, Goldoni, Ca, Golizia, Mg, Grandi, L, Greco, A, Guarda, L, Guttadauro, A, Guzzinati, S, Iannelli, A, Ieni, A, Intrieri, T, Kaleci, S, Lando, C, Lavecchia, Am, Lazzarato, F, Le Rose, L, Leone, A, Leone, R, Lombardo, C, Lonati, F, Lucchi, S, Macci, L, Macerata, V, Madeddu, A, Maffei, S, Maghini, A, Magnani, C, Magnani, G, Magoni, M, Mallone, Sandra, Mancini, S, Mancuso, P, Mangone, L, Mangone, L, Mangone, Lucia, Manneschi, G, Mannino, R, Mannino, S, Mannino, Salvatore, Marani, E, Mariani, F, Martorana, C, Marzola, L, Maspero, S, Maule, M, Mazzei, A, Mazzoleni, G, Mazzucco, G, Melcarne, A, Merletti, F, Merlo, E, Michiara, M, Migliari, E, Minerba, S, Minicuzzi, A, Mizzi, M, Monetti, D, Morana, G, Moroni, E, Mosso, Ml, Muni, A, Mura, F, Natali, M, Negrino, L, Nemcova, L, Nicita, C, Nocera, V, Paderni, F, Pala, F, Palumbo, M, Panciroli, E, Panico, M, Pannozzo, F, Pascucci, C, Pasolini, A, Pastore, G, Patriarca, S, Pedroni, M, Perrotta, C, Pesce, P, Petrinelli, Am, Petrucci, C, Pezzarossi, A, Pezzuto, L, Piccinni, L, Pierannunzio, Daniela, Piffer, S, Pinon, M, Pinto, A, Pintori, N, Pirino, D, Pironi, V, Ponz de Leon, M, Prandi, R, Prazzoli, R, Puleio, M, Puppo, A, Quarta, F, Quattrocchi, M, Raho, Am, Ramazzotti, V, Rashid, I, Ravaioli, A, Ravazzolo, B, Ravegnani, M, Reggiani-Bonetti, L, Ricci, P, Rizzello, R, Rognoni, M, Rollo, Pc, Romanelli, A, Roncaglia, F, Roncucci, L, Rosano, A, Rossi, F, Rossi, G, Rossi, M, Rossi, Silvia, Rossini, S, Rosso, S, Rudisi, G, Ruggeri, Mg, Russo, Ag, Ruzza, Mr, Sacchettini, C, Sacchetto, L, Sacco, G, Sacerdote, C, Sala, O, Salvi, O, Sampietro, G, Santucci, C, Scheibel, M, Sciacca, S, Sciacchitano, C, Sciacchitano, S, Scuderi, T, Sechi, O, Seghini, P, Senatore, G, Sensi, F, Serraino, D, Sgargi, P, Sini, Gm, Sobrato, I, Solimene, C, Spagnoli, G, Spano, F, Spata, E, Sperduti, I, Spinosa, S, Staiti, R, Stocco, C, Storchi, C, Stracci, F, Sunseri, R, Susini, N, Sutera Sardo, A, Tagliabue, G, Tamburo, L, Tamburrino, S, Taranto, V, Tavilla, Andrea, Terracini, B, Tisano, F, Tittarelli, A, Tognazzo, S, Tognazzo, Sandro, Torrisi, A, Torrisi, A, Traina, A, Trama, Annalisa, Trapani, C, Tschugguel, B, Tumino, R, Tumino, Rosario, Usala, M, Vacirca, S, Valente, N, Valerio, O, Valla, K, Varvarà, M, Vasquez, E, Vassante, B, Vattiato, R, Vercellino, Pc, Vicentini, M, Vicentini, Massimo, Villa, M, Visoli, C, Vitale, F, Vitale, Maria Francesca, Vitale, Mf, Vitali, B, Vitali, Me, Vitarelli, S, Vittadello, F, Zanchi, A, Zanetti, R, Zani, G, Zanier, L, Zappa, M, Zarcone, M, Ziino, Ac, Zorzi, M, Zucchetto, A, Zucchi, A +374 morecore +1 more sourceHumanized immune system animal models and their recent applications
Animal Models and Experimental Medicine, EarlyView.In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade +6 morewiley +1 more source
