Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation [PDF]
, 2009 We show that Indian Hedgehog (Ihh) regulates T-cell development and homeostasis in both fetal and adult thymus, controlling thymocyte number. Fetal Ihh-/- thymi had reduced differentiation to double-positive (DP) cell and reduced cell numbers compared ...
Outram, Susan V +17 more
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Thymic mucosa-associated lymphoid tissue lymphoma in a patient with Sjögren’s syndrome with cutaneous vasculitis [PDF]
Vojnosanitetski PregledIntroduction. The association between Sjögren’s syndrome (SS) and the development of lymphoma is well known. The prevalence of lymphoma in patients with SS is 5%.
Božić Ksenija +3 more
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Thymomas With Intravascular and Intracardiac Growth
Frontiers in Oncology, 2022 Thymomas are derived from the epithelial component of the thymus and constitute the most common tumor of the anterior mediastinum. These neoplasms are considered malignant for their potential for invasion and metastases.
Andrea Valeria Arrossi +3 more
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Results of radiotherapy for thymoma: retrospective cohort and propensity score matching analysis [PDF]
Jornal Brasileiro de PneumologiaObjective: Thymic tumors are a rare group of anterior mediastinal tumors. Surgery is the primary treatment. Adjuvant treatment is used in select cases.
Jordana de Paula Soares +6 more
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BENIGN AND MALIGNANT CARDIAC AND MEDIASTINAL MASSES IN CHILDREN
Alʹmanah Kliničeskoj Mediciny, 2016 The authors have summarized their experience of surgical treatment of cardiac and mediastinal neoplasms in 24 pediatric patients who were operated and followed up from 1967 to 2012.
M. A. Martakov, V. T. Selivanenko
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Delta-like 4 is indispensable in thymic environment specific for T cell development. [PDF]
, 2008 The thymic microenvironment is required for T cell development in vivo. However, in vitro studies have shown that when hematopoietic progenitors acquire Notch signaling via Delta-like (Dll)1 or Dll4, they differentiate into the T cell lineage in the ...
Habu, S. +29 more
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In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
FEBS Open Bio, EarlyView.In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
Uncommon Presentations of Pancreatic Neoplasms, Rare Neoplasms, and Peripancreatic Masses
, 2022 Pancreatic masses with atypical radiological appearance are frequently encountered. Atypical presentation of common pancreatic tumor is also possible.
Antonia Olivieri +8 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Клинический разбор в общей медицинеThymic neoplasms are rare in prevalence among the general population. The most common benign formation of the anterior mediastinum is thymus cyst, while thymoma is the most common malignant tumor of the mediastinum.
Zavir M. Salimov +15 more
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