Results 11 to 20 of about 600,981 (261)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T-Cell Immunity. [PDF]

Adv Sci (Weinh)
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Wang S, Zhang Z, Dai F, Yin Z, Xing Z, Li Y, Lei H, Zhang J, Liu C, Li Y, Dong L.   +10 more
europepmc   +2 more sources

Molecular profiling and target actionability for precision medicine in neuroendocrine neoplasms: real-world data.

European Journal of Cancer, 2023
BACKGROUND Key molecular alterations (MA) of neuroendocrine neoplasm (NEN) of various grade/primaries have been described but the applicability of molecular profiling (MP) for precision medicine in NEN remains to be demonstrated. METHODS We conducted a
A. Boilève, M. Faron, S. Fodil-Cherif, A. Bayle, L. Lamartina, D. Planchard, L. Tselikas, C. Kanaan, J. Scoazec, M. Ducreux, A. Italiano, E. Baudin, J. Hadoux   +12 more
semanticscholar   +1 more source

Gene fusions are frequent in ACTH-secreting neuroendocrine neoplasms of the pancreas, but not in their non-pancreatic counterparts

Virchows Archiv, 2023
Ectopic Cushing syndrome is a rare clinical disorder resulting from excessive adrenocorticotrophic hormone (ACTH) produced by non-pituitary neoplasms, mainly neuroendocrine neoplasms (NENs) of the lung, pancreas, and gastrointestinal tract, and other ...
A. Agaimy, A. Kasajima, R. Stoehr, F. Haller, C. Schubart, L. Tögel, N. Pfarr, A. von Werder, M. Pavel, F. Sessa, S. Uccella, S. La Rosa, G. Klöppel   +12 more
semanticscholar   +1 more source

Review of clinical and diagnostic imaging of the thymus: from age-related changes to thymic tumors and everything in between

Japanese Journal of Radiology, 2023
The thymus, a primary lymphoid organ of the immune system, undergoes several changes due to a variety of reasons, ranging from aging to pathological conditions.
Daisuke Yamada, Masaki Matsusako, Yasuyuki Kurihara   +2 more
semanticscholar   +1 more source

Thymic Epithelial Neoplasms: Focusing on the Epigenetic Alterations

International Journal of Molecular Sciences, 2022
Thymic Epithelial Neoplasms (TENs) represent the most common tumors of the thymus gland. Epigenetic alterations are generally involved in initiation and progression of various cancer entities.
Iason Psilopatis, Alexandros Pergaris, Kleio Vrettou, S. Theocharis, C. Troungos   +4 more
semanticscholar   +1 more source

Pictorial essay. Pathology of the thymus on CT-imaging.

Journal of the Belgian Society of Radiology, 2012
A number of masses arise in relation to the thymus. The radiologist has an important role regarding the differential diagnosis between non-tumoral thymic pathology and malignant thymic tumors.
R Peters, O Peters, S Braak, J Verschakelen   +3 more
doaj   +1 more source

The value of thymus and activation related chemokine immunohistochemistry in classic Hodgkin lymphoma diagnostics

Histopathology, 2022
Classic Hodgkin lymphoma (cHL) should be distinguished from its wide variety of histological mimics, including reactive conditions and mature B and T cell neoplasms.
Melvin J. Kilsdonk, Carlijn Veldman, S. Rosati, W. Plattel, A. Diepstra   +4 more
semanticscholar   +1 more source

Huge thymic cyst in an adult

Journal of the Belgian Society of Radiology, 2012
Background: A 28-year-old male smoker (6 pack-years) presented with complaints of dyspnea, cough and chest pain. Physical examination was unremarkable except for decreased respiratory sounds within anterior mid-lung zones bilaterally. Laboratory findings
N Karabulut, D Herek, S¸ Çalis¸kan
doaj   +1 more source

Recent advances and conceptual changes in the classification of neuroendocrine tumors of the thymus

Virchows Archiv, 2021
Neuroendocrine tumors of the thymus (TNET) are exceedingly rare neoplasms. Their histomorphology is identical to neuroendocrine tumors elsewhere in the body (in particular the lungs) and bears no similarity with thymomas and thymic carcinomas.
H. Bohnenberger, Philipp Ströbel
semanticscholar   +1 more source

Atypical primary carcinoid tumor of the thymus

Journal of the Belgian Society of Radiology, 2014
Background: A 65-year-old man presented with slight cough and throat ache for one month. The complaints largely disappeared under medical treatment. Clinical examination and laboratory results showed no significant abnormalities.
L Blockx, K Ramboer
doaj   +1 more source