Results 51 to 60 of about 600,981 (261)

Insulinoma-Associated Protein-1 Expression in Lymphoepithelial Carcinoma of the Thymus: A Potential Pitfall for Diagnosis With Neuroendocrine Carcinomas of the Thymus.

Archives of Pathology & Laboratory Medicine
CONTEXT.— Insulinoma-associated protein-1 (INSM1) is a recently developed immunohistochemical marker claimed to be highly specific and sensitive for the diagnosis of neuroendocrine malignancies. Recent studies, however, have demonstrated that this marker
D. Suster, A. Mackinnon, Saul Suster
semanticscholar   +1 more source

Innovations in Thymoma Diagnosis and Evolution of Treatment Strategies

Zhongliu Fangzhi Yanjiu
Thymic epithelial tumors (TETs) are the most common primary tumors in the anterior mediastinum. They are characterized by a high degree of biological heterogeneity.
Yehong LI, Hui TIAN
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Physiology and immunology of the thymus gland

, 2008
The thymus is a giand located in the upper anteriorportion of the chest cavity just behind the sternurn,Under the evolutionary pressure exerted by the emergence of adaptive immunityAnd its inherent risk to from receptorsThat recognize self molecules ...
TROIANO, Leonarda, PINTI, Marcello, Leonarda Troiano, COSSARIZZA, Andrea, Andrea Cossarizza, NASI, Milena, Milena Nasi, Marcello Pinti   +7 more
core   +1 more source

FIP1L1‐PDGFRA fusion gene in T‐lymphoblastic lymphoma: A case report

Cancer Reports, 2023
Background T‐lymphoblastic lymphoma (T‐LBL) is an aggressive malignancy of T‐lymphoid precursors, rarely co‐occurring with myeloid/lymphoid neoplasms with eosinophilia (M/LNs‐Eo), with consequent rearrangement of tyrosine kinase (TK)‐related genes.
Salhah Ali, Yasmine Al‐Qattan, Walaa Awny, Abdulaziz Hamadah, Karen Pinto, Salem AlShemmari   +5 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Thymic carcinoma

Clinical and Biomedical Research, 2016
Thymic carcinomas are a heterogeneous group of aggressive, invasive epithelial malignancies. Their incidence is rare, occurring predominantly in middle-aged men. Here we present the typical imaging findings of a thymic carcinoma.
Vitória Homem Machado, Fernando Pivatto Júnior, Felipe Soares Torres   +2 more
doaj   +2 more sources

Metastatic Thymic Mucoepidermoid Carcinoma: The Diagnostic Challenges and Role of CRTC1/MAML2 Translocation in Accurate Diagnosis and Treatment

Thoracic Cancer
Mucoepidermoid carcinoma (MEC) is a subtype of epithelial neoplasms commonly found in salivary glands, but can also be seen in the thymus. Diagnosing MEC of the thymus is sometimes challenging due to its histological similarities with adenosquamous ...
Toshiaki Takahashi, Daniel Graham, Evan Wu   +2 more
doaj   +1 more source

Congenital thymoma

Autopsy and Case Reports, 2021
Thymomas are a heterogeneous group of tumors arising from the epithelium of the thymus. They are categorized by the proportion of neoplastic epithelia to lymphocytes and by the degree of cytologic atypia.
Momal Tara Chand, Jacob Edens, Tayson Taixin Lin, David Goshorn, Truc Pham   +4 more
doaj  

Gastrointestinal tract carcinoid with carcinoid syndrome in 63-year-old diver – a case report

Journal of Education, Health and Sport, 2023
Introduction: Carcinoid is a tumor that originates from neuroendocrine cells.[1] It was primarily named and described in 1907 by Siegfried Oberndorfer to characterize neoplasms located in GIST with a relatively indolent course.[2] Term “carcinoid” is ...
Hanna Dominik, Wojciech Pawęska, Barbara Dominik   +2 more
doaj   +1 more source