Results 51 to 60 of about 37,446 (289)

Proteomic Analysis of Neuroendocrine Tumours of the Thymus and Lung

, 2023
Neuroendokrine Tumoren des Thymus sind sehr seltene Neoplasien. Als nächstverwandte Tumorgruppe gelten die neuroendokrinen Tumoren der Lunge. Beide werden nach den gleichen Kriterien in die vier Subtypen typisches Karzinoid, atypisches Karzinoid ...
Bodemeyer, Julius
core   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

Innovations in Thymoma Diagnosis and Evolution of Treatment Strategies

Zhongliu Fangzhi Yanjiu
Thymic epithelial tumors (TETs) are the most common primary tumors in the anterior mediastinum. They are characterized by a high degree of biological heterogeneity.
Yehong LI, Hui TIAN
doaj   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

FIP1L1‐PDGFRA fusion gene in T‐lymphoblastic lymphoma: A case report

Cancer Reports, 2023
Background T‐lymphoblastic lymphoma (T‐LBL) is an aggressive malignancy of T‐lymphoid precursors, rarely co‐occurring with myeloid/lymphoid neoplasms with eosinophilia (M/LNs‐Eo), with consequent rearrangement of tyrosine kinase (TK)‐related genes.
Salhah Ali, Yasmine Al‐Qattan, Walaa Awny, Abdulaziz Hamadah, Karen Pinto, Salem AlShemmari   +5 more
doaj   +1 more source

Overview of the 2022 WHO Classification of Thyroid Neoplasms

, 2022
This review summarizes the changes in the 5th edition of the WHO Classification of Endocrine and Neuroendocrine Tumors that relate to the thyroid gland.
Asa, SL, Asa, Sylvia L, Juhlin, CC, Barletta, Justine A, Ghossein, Ronald A, Jung, CK, Mete, Ozgur, Jung, Chan Kwon, Barletta, JA, Tallini, G, Ghossein, RA, Tallini, Giovanni, Baloch, ZW, LiVolsi, VA, Sobrinho-Simões, Manuel, Juhlin, C Christofer, Papotti, MG, Baloch, Zubair W, LiVolsi, Virginia A, Papotti, Mauro G, Sobrinho-Simoes, M   +20 more
core   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source

Thymic carcinoma

Clinical and Biomedical Research, 2016
Thymic carcinomas are a heterogeneous group of aggressive, invasive epithelial malignancies. Their incidence is rare, occurring predominantly in middle-aged men. Here we present the typical imaging findings of a thymic carcinoma.
Vitória Homem Machado, Fernando Pivatto Júnior, Felipe Soares Torres   +2 more
doaj   +2 more sources

Metastatic Thymic Mucoepidermoid Carcinoma: The Diagnostic Challenges and Role of CRTC1/MAML2 Translocation in Accurate Diagnosis and Treatment

Thoracic Cancer
Mucoepidermoid carcinoma (MEC) is a subtype of epithelial neoplasms commonly found in salivary glands, but can also be seen in the thymus. Diagnosing MEC of the thymus is sometimes challenging due to its histological similarities with adenosquamous ...
Toshiaki Takahashi, Daniel Graham, Evan Wu   +2 more
doaj   +1 more source