Results 101 to 110 of about 75,403 (287)
The FEBS Journal, EarlyView.NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu +9 more
wiley +1 more source
Endocrine Connections, 2019 Objective: Thyroid nodules are usually accompanied by elevated thyroglobulin (Tg) level and autoimmune thyroid diseases (AITDs). However, the relationship between Tg and AITDs is not fully understood.
Yun Hu +11 more
doaj +1 more source
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
The FEBS Journal, EarlyView.Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
Comparative evaluation of two automated immunoassays for serum thyroglobulin quantification [PDF]
Kosin Medical JournalBackground We evaluated the clinical performance of in vitro diagnostic devices for quantifying thyroglobulin (Tg), which is a key marker for monitoring and treating thyroid dysfunction.
Kyoung Ho Roh, Hyunyong Hwang
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The genomes and history of domestic animals [PDF]
, 2016 This paper reviews how mammalian genomes are utilized in modern genetics for the detection of genes and polymorphisms (mutations) within domesticated animal (mostly livestock) genomes that are related to traits of economic importance to humans.
Larkin, D M, Yudin, N S
core +2 more sources
Journal of Diabetes Investigation, EarlyView.Hypothyroidism is an independent risk factor for cognitive impairment in T2DM patients, with a progressive risk increase associated with higher TSH levels. These findings underscore the importance of integrating thyroid function evaluation into the cognitive assessment and management strategy for this patient population.
Mengmeng Zheng, Xing Zhong, Ping Zhang
wiley +1 more source
Cogent Medicine, 2017 Difference in thyroid function depending on the etiology of end-stage renal disease (ESRD) was evaluated in 124 Japanese patients on haemodialysis (HD) due to either chronic glomerulonephritis (CGN, n = 82) or lifestyle related systemic disease (non-CGN,
Toru Sanai +6 more
doaj +1 more source
Searching for LADA in patients with Hashimoto's thyroiditis: A tool for the prevention of LADA
Journal of Diabetes Investigation, EarlyView.ABSTRACT Autoimmune thyroid diseases (AITD), such as Hashimoto's thyroiditis (HT), frequently co‐occur with autoimmune diabetes, including latent autoimmune diabetes in adults (LADA). While guidelines recommend thyroid autoantibody screening in patients with autoimmune diabetes, the reverse approach—screening for diabetes‐related autoantibodies in AITD
Kozlowska Alicja Anna +2 more
wiley +1 more source
Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case–Control Study
Oral Diseases, EarlyView.ABSTRACT Objective To analyze the association between oral lichen planus (OLP), oral lichenoid lesions (OLL), and other comorbidities. Material and Methods A case–control study of 205 OLP, 96 OLL patients, and 301 age‐ and sex‐matched controls from Kuopio University Hospital was performed.
Mari Vehviläinen +3 more
wiley +1 more source
Revista Colombiana de Ciencias Pecuarias, 2012 La terneza y el marmoreo son características poligénicas e indicadoras de calidad en la carne bovina. Uno de los genes relacionados con la terneza en la carne es el gen de µ-calpaína (CAPN), en el cual se han identificado dos polimorfismos CAPN316 ...
Carmen Y Muñoz Mejía +6 more
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