Results 11 to 20 of about 34,213 (236)

A Mathematical Model of Thyroid Disease Response to Radiotherapy [PDF]

open access: yesMathematics 2021, 9(19), 2365, 2021
We present a mechanistic biomathematical model of molecular radiotherapy of thyroid disease. The general model consists of a set of differential equations describing the dynamics of different populations of thyroid cells with varying degrees of damage caused by radiotherapy (undamaged cells, sub-lethally damaged cells, doomed cells, and dead cells), as
arxiv   +1 more source

Intermediate-risk thyroid carcinoma: indicators of a poor prognosis

open access: yesArchives of Endocrinology and Metabolism, 2020
Objective: The intermediate-risk (IR) category includes tumors with different degrees of aggression. We aimed to identify the risk factors associated with unfavorable response to initial treatment and compare the effect of low/high radioactive iodine ...
Fernanda Nascimento Faro   +6 more
doaj   +1 more source

Analysis of factors associated with the prognosis of papillary thyroid cancer and the construction of a survival model

open access: yesCancer Medicine, 2023
Objective To study the survival prediction value of lymph node ratio (LNR) and preoperative thyroglobulin (Tg) in the prognosis of thyroid papillary carcinoma (PTC). Methods A total of 495 patients with PTC and lymph node metastasis treated at the Cancer
Peng Guo   +4 more
doaj   +1 more source

Thyroglobulin/thyrotropin ratio for predicting long-term response in differentiated thyroid carcinoma: a retrospective study

open access: yesArchives of Endocrinology and Metabolism, 2021
Objective: Thyrotropin-stimulated thyroglobulin (STg) after total thyroidectomy is a prognosis marker for differentiated thyroid carcinoma (DTC). As Tg level is influenced by thyrotropin (TSH), perhaps the STg/TSH ratio is also a prognosis marker for ...
Adriano Francisco De Marchi Junior   +9 more
doaj   +1 more source

Central Compartment Lymph Nodes Have Distinct Metastatic Patterns in Different Age Groups

open access: yesFrontiers in Endocrinology, 2022
Background and PurposeCentral compartment lymph node metastasis (CLNM) is a manifestation of tumor aggressiveness and an indicator of tumor prognosis. The purpose of this study was to construct a nomogram for evaluating CLNM patterns in papillary thyroid
Caigu Yan   +3 more
doaj   +1 more source

Thyroglobulin and thyroglobulin antibody: an updated clinical and laboratory expert consensus

open access: yesEuropean Journal of Endocrinology, 2023
AbstractObjectiveThyroglobulin measurement is the cornerstone of modern management of differentiated thyroid cancer, with clinical decisions on treatment and follow-up based on the results of such measurements. However, numerous factors need to be considered regarding measurement with and interpretation of thyroglobulin assay results.DesignThe present ...
Luca Giovanella   +17 more
openaire   +2 more sources

Effect of Thyroglobulin Autoantibodies on the Metabolic Clearance of Serum Thyroglobulin [PDF]

open access: yesThyroid, 2018
In order to establish whether thyroglobulin autoantibodies (TgAb) influence the metabolic clearance of thyroglobulin (Tg) in humans, serum Tg and TgAb were correlated shortly after radioiodine (131I) treatment.Samples were collected from 30 consecutive patients undergoing 131I activity for Graves' hyperthyroidism at the time of treatment and every 15 ...
Latrofa F   +7 more
openaire   +4 more sources

Phylogenetic analysis of the human thyroglobulin regions

open access: yesThyroid Research, 2012
Thyroglobulin is a large protein present in all vertebrates. It is synthesized in the thyrocytes and exported to lumen of the thyroid follicle, where its tyrosine residues are iodinated .
Belkadi Abdelaziz   +3 more
doaj   +1 more source

Analysis of factors influencing the clinical outcome after surgery and 131I therapy in patients with moderate-risk thyroid papillary carcinoma

open access: yesFrontiers in Endocrinology, 2022
PurposeGenerally, the prognosis for papillary thyroid cancer (PTC) is favorable. However, the moderate risk involved warrants further evaluation. Hence, we investigated the clinical outcomes in patients with moderate-risk PTC following surgery and the ...
Yixuan Li   +6 more
doaj   +1 more source

An inflammatory bowel disease-associated SNP increases local thyroglobulin expression to develop inflammation in miniature dachshunds

open access: yesFrontiers in Veterinary Science, 2023
Inflammatory colorectal polyp (ICRP) in miniature dachshunds (MDs) is a chronic inflammatory bowel disease (IBD) characterized by granulomatous inflammation that consists of neutrophil infiltration and goblet cell hyperplasia in the colon.
Yong Bin Teoh   +19 more
doaj   +1 more source

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